Results 71 to 80 of about 115,997 (337)

Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice

Advanced Science, EarlyView.
PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu, Jin‐Yin Huang, Xing‐Zhe Xu, Ji‐Yu Sun, Dan‐Ni Zou, Jia‐Yao Zhang, Chen Chi, Qi Zhang, Wei‐Cai Liu   +8 more
wiley   +1 more source

Central neuromechanisms underlying control of intragastric pressure through acupuncture at Zusanli (ST36) in rats: the upper cervical cord is the key link between the ascending and descending pathways

Neural Regeneration Research, 2016
Sensory inputs stimulated by Zusanli (ST36) acupuncture in the abdomen are known to converge in the upper cervical cord. However, it is unclear whether these inputs are subsequently conveyed to the hypothalamic paraventricular nucleus and what kind of ...
Chun-yan Yong, Shu Chen, Heng Chen, Xiao Chu, Chao Zhang, Cheng Tan, Lan Ye, Jiang-shan Li   +7 more
doaj   +1 more source

Strategies to augment volitional and reflex function may improve locomotor capacity following incomplete spinal cord injury [PDF]

, 2018
Many studies highlight the remarkable plasticity demonstrated by spinal circuits following an incomplete spinal cord injury (SCI). Such plasticity can contribute to improvements in volitional motor recovery, such as walking function, although similar ...
Hornby, T. George, Kim, Hyosub E., Leech, Kristan A.   +2 more
core   +1 more source

Nanographene Oxide Attenuates Acute GVHD by Modulating Macrophage Polarization in a Xenogeneic Mouse Model

Advanced Science, EarlyView.
Nanographene oxide (NGO) attenuates graft‐versus‐host disease (GVHD) severity by inhibiting STAT1‐mediated M1 macrophage polarization and suppressing T‐cell activation. NGO‐primed macrophages (NGO‐Mac) further enhance regulatory T‐cell induction via IL‐10. Both NGO and NGO‐Mac therapies mitigate inflammation and immune pathology, offering cell‐free and
Aaron Yu, Hyun Sung Park, Dong‐Hoon Chae, Jae Han Park, Jiyoung Heo, Keonwoo Cho, Jiho Kim, Hyewon Lee, Sueyeon Jee, Chanwoo Kim, Soon Won Choi, Jaechul Ryu, Eun‐Hye Hur, Yunsuk Choi, Eun‐Ji Choi, Mi‐Kyung Oh, Hwa‐Yong Lee, Je‐Hwan Lee, Kyung‐Rok Yu   +18 more
wiley   +1 more source

K252a Prevents Microglial Activation Induced by Anoxic Stimulation of Carotid Bodies in Rats

Toxics, 2023
Inducing carotid body anoxia through the administration of cyanide can result in oxygen deprivation. The lack of oxygen activates cellular responses in specific regions of the central nervous system, including the Nucleus Tractus Solitarius, hypothalamus,
Ricardo Cuéllar-Pérez, Fernando Jauregui-Huerta, Yaveth Ruvalcaba-Delgadillo, Sergio Montero, Mónica Lemus, Elena Roces de Álvarez-Buylla, Joaquín García-Estrada, Sonia Luquín   +7 more
doaj   +1 more source

A direct cerebello-telencephalic projection in an electrosensory mormyrid fish [PDF]

, 1990
After injections of the posterior part of the lateral zone of the area dorsalis telencephali (Dlp) with either horseradish peroxidase or the newly available carbocyanine dye DiI, efferent cells were labeled in the valvula cerebelli of the mormyrid fish ...
Ebbesson, Echteler, Erdl, Finger, Finger, Finger, Godement, Hanker, Lissman, Meek, Murakami, Murakami, Nieuwenhuys, Nieuwenhuys, Nieuwenhuys, Northcutt, Rooney, Russell, Szabo, Weston, Wullimann, Wullimann, Wullimann   +22 more
core   +1 more source

Sympathetic Activation Promotes Kidney Fibrosis in Mice via Macrophage‐Derived N2ICD‐Enriched Extracellular Vesicles

Advanced Science, EarlyView.
Norepinephrine/α2B‐adrenoceptor axis promotes the secretion of Notch2 intracellular domain (N2ICD)‐enriched extracellular vesicles (EVs) from macrophages. These EVs deliver N2ICD into fibroblasts, thereby inducing their activation. Deletion of Notch2 or α2B‐AR in macrophages disrupts N2ICD‐enriched EV formation and alleviates kidney fibrosis in mice ...
Huiwen Ren, Yayan Hou, Chengsen Mu, Yinghong Zheng, Yuanyang Wang, Shumin Guo, Lu Wang, Wenlong Shang, Zhuming Yin, Cheng Dong, Yongsheng Chang, Bin Zhou, Renjie Chai, Ying Yu, Yujun Shen   +14 more
wiley   +1 more source

Brain-actuated functional electrical stimulation elicits lasting arm motor recovery after stroke

Nature Communications, 2018
Brain-computer interface (BCI) can improve motor skills on stroke patients. This study shows that BCI-controlled neuromuscular electrical stimulation therapy can cause cortical reorganization due to activation of efferent and afferent pathways, and this ...
A. Biasiucci, R. Leeb, I. Iturrate, S. Perdikis, A. Al-Khodairy, T. Corbet, A. Schnider, T. Schmidlin, H. Zhang, M. Bassolino, D. Viceic, P. Vuadens, A. G. Guggisberg, J. d. R. Millán   +13 more
doaj   +1 more source

Spinal Afferent Innervation of the Colon and Rectum

Frontiers in Cellular Neuroscience, 2018
Despite their seemingly elementary roles, the colon and rectum undertake a variety of key processes to ensure our overall wellbeing. Such processes are coordinated by the transmission of sensory signals from the periphery to the central nervous system ...
Stuart M. Brierley, Stuart M. Brierley, Timothy J. Hibberd, Nick J. Spencer   +3 more
doaj   +1 more source

Central Organization of Afferent Renal Nerve Pathways

Clinical and Experimental Hypertension. Part A: Theory and Practice, 1987
Although afferent renal nerves have been studied for over a quarter of a century, their physiological role remains unclear. There is considerable experimental evidence indicating that afferent renal nerves convey sensory information from renal receptors to integrative circuits in the central nervous system which gives rise to command signals ...
John Ciriello, Monica M. Caverson
openaire   +3 more sources