Results 51 to 60 of about 54,077 (165)
Cooperative Oxygen Sensing by the Kidney and Carotid Body in Blood Pressure Control
Frontiers in Physiology, 2017 Oxygen sensing mechanisms are vital for homeostasis and survival. When oxygen levels are too low (hypoxia), blood flow has to be increased, metabolism reduced, or a combination of both, to counteract tissue damage.
Daniela Patinha +5 more
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Central and peripheral contributions of T-type calcium channels in pain
Molecular Brain, 2022 Chronic pain is a severely debilitating condition that reflects a long-term sensitization of signal transduction in the afferent pain pathway. Among the key players in this pathway are T-type calcium channels, in particular the Cav3.2 isoform. Because of
Erika K. Harding, Gerald W. Zamponi
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Anatomical and molecular properties of long descending propriospinal neurons in mice [PDF]
, 2017 Long descending propriospinal neurons (LDPNs) are interneurons that form direct connections between cervical and lumbar spinal circuits. LDPNs are involved in interlimb coordination and are important mediators of functional recovery after spinal cord ...
Boyle, Kieran +8 more
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Neural Regeneration Research, 2016 Sensory inputs stimulated by Zusanli (ST36) acupuncture in the abdomen are known to converge in the upper cervical cord. However, it is unclear whether these inputs are subsequently conveyed to the hypothalamic paraventricular nucleus and what kind of ...
Chun-yan Yong +7 more
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Brain-actuated functional electrical stimulation elicits lasting arm motor recovery after stroke
Nature Communications, 2018 Brain-computer interface (BCI) can improve motor skills on stroke patients. This study shows that BCI-controlled neuromuscular electrical stimulation therapy can cause cortical reorganization due to activation of efferent and afferent pathways, and this ...
A. Biasiucci +13 more
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Spinal Afferent Innervation of the Colon and Rectum
Frontiers in Cellular Neuroscience, 2018 Despite their seemingly elementary roles, the colon and rectum undertake a variety of key processes to ensure our overall wellbeing. Such processes are coordinated by the transmission of sensory signals from the periphery to the central nervous system ...
Stuart M. Brierley +3 more
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Exercise intolerance and fatigue in chronic heart failure: is there a role for group III/IV afferent feedback? [PDF]
, 2020 Exercise intolerance and early fatiguability are hallmark symptoms of chronic heart failure. While the malfunction of the heart is certainly the leading cause of chronic heart failure, the patho-physiological mechanisms of exercise intolerance in these ...
Angius, Luca, Crisafulli, Antonio
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Strategies to augment volitional and reflex function may improve locomotor capacity following incomplete spinal cord injury [PDF]
, 2018 Many studies highlight the remarkable plasticity demonstrated by spinal circuits following an incomplete spinal cord injury (SCI). Such plasticity can contribute to improvements in volitional motor recovery, such as walking function, although similar ...
Hornby, T. George +2 more
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Scientific ReportsHow afferent input shapes synaptic connections is fundamental to our understanding of cues that govern assembly of sensory circuits. In the retina, photoreceptors provide afferent visual information to second-order bipolar cells (BCs) that in turn ...
Julie Wallin +3 more
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Pathologic fracture of mandibular ramus in a patient with familial dysautonomia: A case report
Oral and Maxillofacial Surgery CasesFamilial dysautonomia is a rare disease that impairs the development of sensory nerves, afferent autonomic nerves, and afferent baroreflex pathways.
Patrick J. Nolan +2 more
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