Results 31 to 40 of about 68,911 (310)

Neuronal regulation of the gut immune system and neuromodulation for treating inflammatory bowel disease

open access: yesFASEB BioAdvances, 2021
The gut immune system in the healthy intestine is anti‐inflammatory, but can move to a pro‐inflammatory state when the gut is challenged by pathogens or in disease.
Luis Populin   +2 more
doaj   +1 more source

Group I afferent pathway contributes to functional knee stability

open access: yes, 2010
*This article is free to read on the publisher's website*\ud \ud The hamstring reflex response has been suggested to play a substantial role in knee joint stabilization during anterior tibial translation.
Friemert, Benedikt   +4 more
core   +1 more source

Serotonin, dopamine and noradrenaline adjust actions of myelinated afferents via modulation of presynaptic inhibition in the mouse spinal cord.

open access: yesPLoS ONE, 2014
Gain control of primary afferent neurotransmission at their intraspinal terminals occurs by several mechanisms including primary afferent depolarization (PAD). PAD produces presynaptic inhibition via a reduction in transmitter release.
David L García-Ramírez   +3 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Somatic influences on subjective well-being and affective disorders: the convergence of thermosensory and central serotonergic systems

open access: yesFrontiers in Psychology, 2015
Current theories suggest that the brain is the sole source of mental illness. However, affective disorders, and major depressive disorder (MDD) in particular, may be better conceptualized as brain-body disorders that involve peripheral systems as well ...
Charles L Raison   +4 more
doaj   +1 more source

Afferent convergence to a shared population of interneuron AMPA receptors

open access: yesNature Communications, 2023
Precise alignment of pre- and postsynaptic elements optimizes the activation of glutamate receptors at excitatory synapses. Nonetheless, glutamate that diffuses out of the synaptic cleft can have actions at distant receptors, a mode of transmission ...
Reagan L. Pennock   +4 more
doaj   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar   +3 more
wiley   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Glucagon-like peptide-1 reduces pancreatic β-cell mass through hypothalamic neural pathways in high-fat diet-induced obese rats

open access: yesScientific Reports, 2017
We examined whether glucagon-like peptide-1 (GLP-1) affects β-cell mass and proliferation through neural pathways, from hepatic afferent nerves to pancreatic efferent nerves via the central nervous system, in high-fat diet (HFD)-induced obese rats.
Hisae Ando   +7 more
doaj   +1 more source

A fuzzy controller for movement stabilization using afferent control: Controller synthesis and simulation

open access: yesJournal of Medical Signals and Sensors, 2017
Stimulation of spinal sensorimotor circuits can improve motor control in animal models and humans with spinal cord injury (SCI). More recent evidence suggests that the stimulation increases the level of excitability in the spinal circuits, activates ...
Zahra Khodadadi   +2 more
doaj   +1 more source

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