Results 1 to 10 of about 127,149 (191)

The influence of Nav1.9 channels on intestinal hyperpathia and dysmotility

open access: yesChannels, 2023
The Nav1.9 channel is a voltage-gated sodium channel. It plays a vital role in the generation of pain and the formation of neuronal hyperexcitability after inflammation. It is highly expressed in small diameter neurons of dorsal root ganglions and Dogiel
Chenyu Zhao, Xi Zhou, Xiaoliu Shi
doaj   +1 more source

Mesencephalic trigeminal nucleus neurons with collaterals to both eyelid and masseter muscles shown by fluorescent double-labeling, revealing a potential mechanism for Marcus Gunn Syndrome.

open access: yesPLoS ONE, 2023
Poking palpebral conjunctiva evoked upper-eyelid retraction during ophthalmic surgery. Iatrogenic eyelid ptosis occurred if eyelid branch of lachrymal nerve was sectioned.
Xue Shi   +3 more
doaj   +1 more source

Electrophysiological properties of maxillary trigeminal Aβ-afferent neurons of rats

open access: yesMolecular Pain, 2021
Aβ-afferents in maxillary or V2 trigeminal ganglion (TG) neurons are somatosensory neurons that may be involved in both non-nociceptive and nociceptive functions in orofacial regions.
Yuya Okutsu   +4 more
doaj   +1 more source

Piezo2 Knockdown Inhibits Noxious Mechanical Stimulation and NGF-Induced Sensitization in A-Delta Bone Afferent Neurons

open access: yesFrontiers in Physiology, 2021
Piezo2 is a mechanically gated ion-channel that has a well-defined role in innocuous mechanical sensitivity, but recently has also been suggested to play a role in mechanically induced pain.
Sara Nencini   +5 more
doaj   +1 more source

Non-nociceptive and nociceptive-like trigeminal Aβ-afferent neurons of rats: Distinct electrophysiological properties, mechanical and chemical sensitivity

open access: yesMolecular Pain, 2023
The role of Aβ-afferents in somatosensory function is often oversimplified as low threshold mechanoreceptors (LTMRs) with large omission of Aβ-afferent involvement in nociception.
Ryan J Vaden, Jianguo G Gu
doaj   +1 more source

A Review of Neural Data and Modelling to Explain How a Semicircular Canal Dehiscence (SCD) Causes Enhanced VEMPs, Skull Vibration Induced Nystagmus (SVIN), and the Tullio Phenomenon

open access: yesAudiology Research, 2023
Angular acceleration stimulation of a semicircular canal causes an increased firing rate in primary canal afferent neurons that result in nystagmus in healthy adult animals.
Ian S. Curthoys   +3 more
doaj   +1 more source

Synaptic plasticity in medial vestibular nucleus neurons: comparison with computational requirements of VOR adaptation [PDF]

open access: yes, 2010
Background: Vestibulo-ocular reflex (VOR) gain adaptation, a longstanding experimental model of cerebellar learning, utilizes sites of plasticity in both cerebellar cortex and brainstem.
Fabien Tell   +4 more
core   +9 more sources

Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons. [PDF]

open access: yesPLoS ONE, 2013
Statoacoustic ganglion (SAG) neurons project sensory afferents to appropriate targets in the inner ear to form functional vestibular and auditory circuits.
Kei-ichi Katayama   +3 more
doaj   +1 more source

Differential regulation of bladder pain and voiding function by sensory afferent populations revealed by selective optogenetic activation [PDF]

open access: yes, 2010
Bladder-innervating primary sensory neurons mediate reflex-driven bladder function under normal conditions, and contribute to debilitating bladder pain and/or overactivity in pathological states. The goal of this study was to examine the respective roles
DeBerry, Jennifer J   +7 more
core   +4 more sources

Evolutionary convergence of a neural mechanism in the cavefish lateral line system

open access: yeseLife, 2022
Animals can evolve dramatic sensory functions in response to environmental constraints, but little is known about the neural mechanisms underlying these changes.
Elias T Lunsford   +3 more
doaj   +1 more source

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