TRPV1 marks synaptic segregation of multiple convergent afferents at the rat medial solitary tract nucleus. [PDF]
PLoS ONE, 2011 TRPV1 receptors are expressed on most but not all central terminals of cranial visceral afferents in the caudal solitary tract nucleus (NTS). TRPV1 is associated with unmyelinated C-fiber afferents.
James H Peters +3 more
doaj +1 more source
Molecular Pain, 2020 The Acid Sensing Ion Channel 3 (ASIC3) is a non-selective cation channel that is activated by acidification, and is known to have a role in regulating inflammatory pain.
Michael Morgan +5 more
doaj +1 more source
Molecular Pain, 2012 Background Migraine and other headache disorders affect a large percentage of the population and cause debilitating pain. Activation and sensitization of the trigeminal primary afferent neurons innervating the dura and cerebral vessels is a crucial step ...
Huang Dongyue +4 more
doaj +1 more source
Neuropharmacological targets for drug action in vestibular sensory pathways [PDF]
, 2017 The use of pharmacological agents is often the preferred approach to the management of vestibular dysfunction. In the vestibular sensory pathways, the sensory neuroepithelia are thought to be influenced by a diverse number of neuroactive substances that ...
Jones, Timothy A, Lee, Choongheon
core +3 more sources
elPBN neurons regulate rVLM activity through elPBN-rVLM projections during activation of cardiac sympathetic afferent nerves. [PDF]
, 2016 The external lateral parabrachial nucleus (elPBN) within the pons and rostral ventrolateral medulla (rVLM) contributes to central processing of excitatory cardiovascular reflexes during stimulation of cardiac sympathetic afferent nerves (CSAN).
Fu, Liang-Wu +3 more
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Molecular Pain, 2023 STOML3 is a membrane bound scaffolding protein that has been shown to facilitate the opening of mechanically sensitive ion channels and contribute to noxious mechanical sensation, allodynia and hyperalgesia.
Michael Morgan +4 more
doaj +1 more source
Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]
, 2015 Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine +2 more
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Prevertebral ganglia and intestinofugal afferent neurones [PDF]
Gut, 2002 Intestinofugal afferent neurones (IFANs) are a unique subset of myenteric ganglion neurones that regulate normal gastrointestinal function. The IFANs relaying mechanosensory information to sympathetic neurones of the prevertebral ganglion (PVG) function as volume detectors.
J H, Szurszewski +2 more
openaire +2 more sources
The Spatial Structure of Stimuli Shapes the Timescale of Correlations in Population Spiking Activity [PDF]
, 2012 Throughout the central nervous system, the timescale over which pairs of neural spike trains are correlated is shaped by stimulus structure and behavioral context.
Abigail Morrison +3 more
core +11 more sources
Contrasting alterations to synaptic and intrinsic properties in upper-cervical superficial dorsal horn neurons following acute neck muscle inflammation [PDF]
, 2014 Background: Acute and chronic pain in axial structures, like the back and neck, are difficult to treat, and have incidence as high as 15%. Surprisingly, most preclinical work on pain mechanisms focuses on cutaneous structures in the limbs and animal ...
Baba H +7 more
core +3 more sources