Results 41 to 50 of about 22,165 (265)

Adaptive Neural Event-Triggered Control of MIMO Pure-Feedback Systems With Asymmetric Output Constraints and Unmodeled Dynamics

open access: yesIEEE Access, 2020
In this paper, the issue of adaptive neural event-triggered control (ETC) is studied for uncertain block-structure multi-input multi-output (MIMO) constrained non-affine nonlinear systems with unmodeled dynamics.
Yu Hua, Tianping Zhang
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Structure and affinity of DNA binding peptides [PDF]

open access: yesNucleic Acids Symposium Series, 2000
Artificial peptides designed to form alpha-helical, beta-turn, antiparallel beta-sheet and beta-hairpin structures which are among the motifs most frequently found in natural DNA/RNA binding proteins were synthesized and their characteristic features were examined in the presence or absence of double or triple stranded DNA by means of UV melting ...
T, Kubo   +10 more
openaire   +2 more sources

Abelization of join spaces of affine transformations of ordered field with proximity

open access: yesApplied General Topology, 2005
Using groups of affine transformations of linearly ordered fields a certain construction of non-commutative join hypergroups is presented based on the criterion of reproducibility of semi-hypergroups which are determined by ordered semigroups. The aim of
Sárka Hosková
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Applications of the Affine Structures on the Teichmüller Spaces [PDF]

open access: yes, 2016
We prove the existence of global sections trivializing the Hodge bundles on the Hodge metric completion space of the Torelli space of Calabi--Yau manifolds, a global splitting property of these Hodge bundles. We also prove that a compact Calabi--Yau manifold can not be deformed to its complex conjugate.
Liu, Kefeng, Shen, Yang, Chen, Xiaojing
openaire   +2 more sources

Flag Gromov-Witten invariants via crystals [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2014
We apply ideas from crystal theory to affine Schubert calculus and flag Gromov-Witten invariants. By defining operators on certain decompositions of elements in the type-$A$ affine Weyl group, we produce a crystal reflecting the internal structure of ...
Jennifer Morse, Anne Schilling
doaj   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

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