Results 51 to 60 of about 22,165 (265)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
The Structure and Affinities of British Tuberaceae
Annals of Botany, 1909 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
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Sensors, 2020 Scanning electron microscopes (SEMs) are versatile imaging devices for the micro- and nanoscale that find application in various disciplines such as the characterization of biological, mineral or mechanical specimen.
Stefan Töberg, Eduard Reithmeier
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Affine Connections on Involutive G-structures [PDF]
, 2021 This paper is a review of the twistor theory of irreducible G-structures and affine connections. Long ago, Berger presented a very restricted list of possible irreducibly acting holonomies of torsion-free affine connections. His list was complete in the part of metric connections, while the situation with holonomies of non-metric torsion-free affine ...
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Peterson-Lam-Shimozono’s theorem is an affine analogue of quantum Chevalley formula
Forum of Mathematics, SigmaWe give a new proof of an unpublished result of Dale Peterson, proved by Lam and Shimozono, which identifies explicitly the structure constants, with respect to the quantum Schubert basis, for the T-equivariant quantum cohomology $QH^{\bullet }_T(G/P)
Chi Hong Chow
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Proceedings - Mathematical Sciences, 1990 We establish a one-to-one correspondence between the set of all equivalence classes of affine Poisson structures (defined on the dual of a finite dimensional Lie algebra) and the set of all equivalence classes of central extensions of the Lie algebra by ℝ.
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