Results 41 to 50 of about 1,391,504 (276)

Estrogen receptor has enhanced affinity for bromodeoxyuridine-substituted DNA. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1978
The estrogen receptor (E2R) from rabbit uterus has an enhanced affinity for BrdUrd-substituted DNA compared to unsubstituted DNA. Increasing levels of BrdUrd substitution (from 0 to 100%) in a DNA sample are associated with increasingly tighter binding of E2R to that DNA as measured by equilibrium competition experiments and by rates of dissociation ...
J, Kallos   +3 more
openaire   +2 more sources

The Hamiltonian of Einstein affine-metric formulation of General Relativity

open access: yes, 2009
It is shown that the Hamiltonian of the Einstein affine-metric (first order) formulation of General Relativity (GR) leads to a constraint structure that allows the restoration of its unique gauge invariance, four-diffeomorphism, without the need of any ...
A. Einstein   +73 more
core   +1 more source

A Large k Asymptotics of Witten's Invariant of Seifert Manifolds

open access: yes, 1993
We calculate a large $k$ asymptotic expansion of the exact surgery formula for Witten's $SU(2)$ invariant of Seifert manifolds. The contributions of all flat connections are identified. An agreement with the 1-loop formula is checked.
C. Lescop   +12 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Self-adaptive encryption algorithm for image based on affine and composed chaos

open access: yesTongxin xuebao, 2012
On the basis of three-dimensional affine transformation in limited integer domain and composed chaos,a novel digital image encryption algorithm was proposed.Firstly,it scrambled pixels’ position and confused pixels’ value according to corresponding ...
Chang-ci WEN   +4 more
doaj   +2 more sources

Improved Vigenere approach incorporating pseudorandom affine functions for encrypting color images

open access: yesInternational Journal of Electrical and Computer Engineering (IJECE)
This article presents an improvement to the traditional Vigenere encryption method, specifically adapted for the encryption of color images. This enhancement relies on the use of two chaotic maps widely employed in the field of cryptography.
Hamid El Bourakkadi   +5 more
semanticscholar   +1 more source

Algebraic Construction of Powerful Substitution Box

open access: yesInternational journal of recent technology and engineering, 2020
The development of wireless transmission, day by day contacts the new statures of innovation. Cryptography is one of the procedures used to give security to information streaming over the system by encryption and decryption. Substitution box (S-box) is a
E. W. Afify   +6 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Improved vigenere using affine functions surrounded by two genetic crossovers for image encryption

open access: yesIndonesian Journal of Electrical Engineering and Computer Science
This paper presents an improved method for encrypting color images, surpassing the effectiveness of genetic crossover and substitution operations. The technique incorporates dynamic random functions to enhance the integrity of the resulting vector ...
Hamid El Bourakkadi   +5 more
semanticscholar   +1 more source

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