Results 111 to 120 of about 258,589 (319)

Participatory Budgeting and the Radical Imagination: In Europe but not in Canada?

, 2010
Participatory budgets are recent interventions that have sought to counter neoliberalism in the global south and north. I critically assess the claim that they constitute new democratic spaces in which marginal and poor citizens create practices of self ...
Maley, Terry
core  

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Density-functional calculations of molecular electron affinities

Journal of the Brazilian Chemical Society, 1999
Electron affinities of twelve small molecules were calculated by density functional theory using two different functionals(B88-P86 and B3LYP) combined with three different basis sets(6-31++G** ; 6-311++G** ; aug-cc-pVTZ).
Takahata Yuji, Chong Delano P.
doaj  

The Affinity Advantage

Journal of Medicinal Chemistry
Drug discovery is a complex, multi-parameter optimization process. I argue that a greater emphasis on optimizing binding affinity will accelerate the development of new medicines. Note that “optimizing” is not always synonymous with “maximizing.” While affinity is certainly not the only thing that matters, the value of optimizing drug – receptor ...
openaire   +2 more sources

\u27We Need to Talk\u27: A Review of Undoing Border Imperialism

, 2014
From the frontlines of the battle against global imperialism, this book both argues for and exemplifies the importance of dialogue within and about radical activism.
Partridge, Kevin
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Margareth Hagen & Margery Vibe Skagen (eds.), Literature and Chemistry – Elective Affinities (Aarhus: Aarhus University Press, 2015)

, 2016
Book review of: Margareth Hagen & Margery Vibe Skagen (eds.), Literature and Chemistry – Elective Affinities (Aarhus: Aarhus University Press, 2015)
Ársæll Már Arnarsson
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The Universe of Worker-Recovered Companies in Argentina (2002-2008): Continuity and Changes Inside the Movement

, 2010
Argentina’s movement of worker-recovered companies (WRC) gained significant public visibility during and in the years following the institutional crisis of December 2001.
Palomino, Héctor, Garro, Silvia, Giacomuzzi, Carla, Bleynat, Ivanna   +3 more
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source