Results 61 to 70 of about 258,589 (319)
Methods for Improving Aptamer Binding Affinity
Molecules, 2016 Aptamers are single stranded oligonucleotides that bind a wide range of biological targets. Although aptamers can be isolated from pools of random sequence oligonucleotides using affinity-based selection, aptamers with high affinities are not always ...
Hijiri Hasegawa +3 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Visioni anarchiche, immaginari islamici. Uno studio sugli isomorfismi spirituali tra l’anarchismo e l’Islam [PDF]
Storia e Politica, 2023 This article aims to offer an overview on how Islamic anarchism can be conceptualized into the field of the history of political thought. This study is divided into three parts: a preliminary analysis of the relationship between the anarchist thought and
Parissa Oskorouchi
doaj
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Modeling Tourist Affinities and Mediated Loyalty in Protected Natural Areas Using Fuzzy Logic
Tourism and HospitalityThis study analyzes tourist loyalty in the Monarch Butterfly Biosphere Reserve by integrating affinity-based segmentation and the Forgotten Effects Theory within a fuzzy logic framework.
Miriam Edith Pérez-Romero +3 more
doaj +1 more source
Selecta Mathematica, 2006 The purpose of this work is to introduce a notion of \emph{affine stacks}, which is a homotopy version of the notion of affine schemes, and to give several applications in the context of algebraic topology and algebraic geometry. As a first application we show how affine stacks can be used in order to give a new point of view (and new proofs) on ...
openaire +2 more sources
Journal Editor\u27s Introduction
, 2011 Journal Editor’s Introduction to Anarch@Indigenism edition of Affinities Journal: “Working Across Difference for Post-Imperial Futures: Intersections Between Anarchism, Indigenism and Feminism.
Day, Richard JF
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Extended affinization of Invariant Affine Reflection Algebras
Osaka Journal of Mathematics, 2011 Invariant affine reflection algebras are the last and the most general known extension of affine Kac-Moody Lie algebras, introduced in recent years. We develop a method known as "affinization" to the class of invariant affine reflection algebras, and show that starting with an algebra from this class together with a certain finite order automorphism ...
Azam, Saeid +2 more
openaire +4 more sources