Results 11 to 20 of about 2,425,944 (351)
Design and characterization of a protein fold switching network
In this work the authors investigate the structure-sequence dependance. The ability to design and characterize proteins at interfaces between three common folds suggests that fold switching is an intrinsic feature of protein folding language and likely ...
Biao Ruan +11 more
doaj +1 more source
Affine Partitions and Affine Grassmannians [PDF]
We give a bijection between certain colored partitions and the elements in the quotient of an affine Weyl group modulo its Weyl group. By Bott's formula these colored partitions give rise to some partition identities. In certain types, these identities have previously appeared in the work of Bousquet-Melou-Eriksson, Eriksson-Eriksson and Reiner.
Billey, Sara C., Mitchell, Stephen C.
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Engineering subtilisin proteases that specifically degrade active RAS
Chen et al. describe a rational design of subtilisin mutants that degrade active RAS by cleaving a conserved sequence in switch 2. They further modified the active site to be dependent on a cofactor to generate high target specificity.
Yingwei Chen +18 more
doaj +1 more source
Antibodies to SARS-CoV-2 and risk of past or future sick leave
The extent that antibodies to SARS-CoV-2 may protect against future virus-associated disease is unknown. We invited all employees (n = 15,300) at work at the Karolinska University Hospital, Stockholm, Sweden to participate in a study examining SARS-Cov-2
Joakim Dillner +19 more
doaj +1 more source
Where are biomedical research plain‐language summaries?
Background and Aims Plain‐language summaries (PLS) are being heralded as a tool to improve communication of scientific research to lay audiences and time‐poor or nonspecialist healthcare professionals.
Hannah FitzGibbon +4 more
doaj +1 more source
We propose a marriage model where assortative matching results in equilibrium for reasons other than those driving similar results in the search and matching literature. A marriage is a joint venture where husband and wife contribute to the couple’s welfare by allocating their time to portfolios of risky activities.
Daniela Di Cagno +2 more
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Background The clinical presentations of frontotemporal dementia (FTD) are diverse and overlap with other neurological disorders. There are, as of today, no biomarkers in clinical practice for diagnosing the disorders.
Julia Remnestål +11 more
doaj +1 more source
Association of CSF proteins with tau and amyloid β levels in asymptomatic 70-year-olds
Background Increased knowledge of the evolution of molecular changes in neurodegenerative disorders such as Alzheimer’s disease (AD) is important for the understanding of disease pathophysiology and also crucial to be able to identify and validate ...
Julia Remnestål +11 more
doaj +1 more source
Age-associated changes in intestinal health biomarkers in dogs
The gut microbiome is critical for maintaining host health. In healthy humans, the aging process is one of the main factors modulating the changes in the intestinal microbiota.
Anna Fernández-Pinteño +5 more
doaj +1 more source
Affine Computation and Affine Automaton [PDF]
23 pages. New results were added. Accepted to CSR2016!
Díaz-Caro, Alejandro +1 more
openaire +2 more sources

