Results 41 to 50 of about 2,330,138 (304)

Dietary Inulin Supplementation Modulates Fecal Microbiota and Vaccine Response in Cats—A Double-Blind Randomized Controlled Pilot Study

open access: yesPets
Twenty-six cats were fed either a control or an inulin-supplemented diet (0.6%) for six weeks with measurements of fecal short-chain fatty acids (SCFAs) and microbiota.
Isabelle C. Jeusette   +7 more
doaj   +1 more source

An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy

open access: yesmAbs, 2022
Monoclonal antibodies targeting the programmed cell death protein 1 (PD-1) remain the most prevalent cancer immunotherapy both as a monotherapy and in combination with additional therapies. Despite the extensive success of anti-PD-1 monoclonal antibodies
Sarah C. Cowles   +7 more
doaj   +1 more source

HELIN Cataloging Policies and Procedures Manual [PDF]

open access: yes, 2011
HELIN Cataloging Manual - Nov.
HELIN Consortium. Cataloging Affinity Group
core   +1 more source

Regional surname affinity: a spatial network approach [PDF]

open access: yes, 2019
OBJECTIVE We investigate surname affinities among areas of modern‐day China, by constructing a spatial network, and making community detection.
Chen, Jiawei   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Classic and Golli Myelin Basic Protein have distinct developmental trajectories in human visual cortex

open access: yesFrontiers in Neuroscience, 2015
Traditionally myelin is viewed as insulation around axons however more recent studies have shown it plays an important role in plasticity, axonal metabolism and neuroimmune signalling.
Caitlin R Siu   +4 more
doaj   +1 more source

Structural and Functional Aspects of G-Quadruplex Aptamers Which Bind a Broad Range of Influenza A Viruses

open access: yesBiomolecules, 2020
An aptamer is a synthetic oligonucleotide with a unique spatial structure that provides specific binding to a target. To date, several aptamers to hemagglutinin of the influenza A virus have been described, which vary in affinity and strain specificity ...
Anastasia A. Novoseltseva   +9 more
doaj   +1 more source

Biological and immunochemical properties of polyreactive immunoglobulins [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2015
A previously unknown phenomenon of acquired polyreactivity of serum immunoglobulins, which were subject to the effect of concentrated solutions of chaotropic ions, such as KSCN (3.0-5.0 M), low/high pH (pH 2.2-3.0), or heating to 58-60 °C, was originally
S. A. Bobrovnik   +2 more
doaj   +1 more source

Affinity Weighted Embedding [PDF]

open access: yes, 2013
Supervised (linear) embedding models like Wsabie and PSI have proven successful at ranking, recommendation and annotation tasks. However, despite being scalable to large datasets they do not take full advantage of the extra data due to their linear ...
Weiss, Ron, Weston, Jason, Yee, Hector
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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