Results 41 to 50 of about 1,578,929 (319)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
PetsTwenty-six cats were fed either a control or an inulin-supplemented diet (0.6%) for six weeks with measurements of fecal short-chain fatty acids (SCFAs) and microbiota.
Isabelle C. Jeusette +7 more
doaj +1 more source
Frontiers in Neuroscience, 2015 Traditionally myelin is viewed as insulation around axons however more recent studies have shown it plays an important role in plasticity, axonal metabolism and neuroimmune signalling.
Caitlin R Siu +4 more
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Affine Anosov Diffeomorphims of Affine Manifolds
International Journal of Mathematics and Mathematical Sciences, 2008 We show that a compact affine manifold endowed with an affine Anosov transformation is finitely covered by a complete affine nilmanifold. This is a partial answer of a conjecture of Franks for affine manifolds.
openaire +5 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy
mAbs, 2022 Monoclonal antibodies targeting the programmed cell death protein 1 (PD-1) remain the most prevalent cancer immunotherapy both as a monotherapy and in combination with additional therapies. Despite the extensive success of anti-PD-1 monoclonal antibodies
Sarah C. Cowles +7 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Epidemiology of Dog and Cat Abandonment in Spain (2008–2013)
Animals, 2015 Millions of pets are abandoned worldwide every year, which is an important animal welfare and financial problem. This paper was divided into three studies.
Jaume Fatjó +6 more
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Biomolecules, 2020 An aptamer is a synthetic oligonucleotide with a unique spatial structure that provides specific binding to a target. To date, several aptamers to hemagglutinin of the influenza A virus have been described, which vary in affinity and strain specificity ...
Anastasia A. Novoseltseva +9 more
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Biological and immunochemical properties of polyreactive immunoglobulins [PDF]
The Ukrainian Biochemical Journal, 2015 A previously unknown phenomenon of acquired polyreactivity of serum immunoglobulins, which were subject to the effect of concentrated solutions of chaotropic ions, such as KSCN (3.0-5.0 M), low/high pH (pH 2.2-3.0), or heating to 58-60 °C, was originally
S. A. Bobrovnik +2 more
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