Results 241 to 250 of about 2,330,138 (304)

FcγR-driven chimeric receptor T cells in cancer therapy: a novel frontier in antibody-guided immunotherapy. [PDF]

Cancer Cell Int
Marei HE, Pozzoli G, Caratelli S, Cenciarelli C.   +3 more
europepmc   +1 more source

Photo‐Controlled Antibacterial Drug Release From DASA‐Coated Silica Particles for Improved Treatment of Wound Infections

Advanced Functional Materials, EarlyView.
Synthesis and characterization of light‐responsive donor–acceptor Stenhouse adducts (DASA)‐coated chlorhexidine‐loaded silica nanoparticles. Such a controllable drug‐delivery system enables the release of the antimicrobial drug on demand and in consecutive cycles, thereby maintaining the concentration within the therapeutic window.
Michèle Clerc, Flavia Zuber, Lea Oberhänsli, Yvonne Elbs‐Glatz, Maria M. Miguel, Vera M. Kissling, Qun Ren, Markus Rottmar, Luciano F. Boesel, Giorgia Giovannini   +9 more
wiley   +1 more source

A Holistic Approach to Identifying a Positron Emission Tomography (PET) Tracer Candidate for In Vivo Imaging of Purinergic P2X7 Receptor in Neuroinflammation. [PDF]

ACS Pharmacol Transl Sci
Ghafir El Idrissi I, Spinaci A, Vitone D, Intranuovo F, Niso M, Brunetti L, Francucci B, Pazarlar BA, Magnusdottir KH, Paradies E, Marobbio CMT, Ricci L, Grignolo M, Iacobazzi RM, Marucci G, Dal Ben D, Lambertucci C, Volpini R, Denora N, Adinolfi E, Mikkelsen JD, Buccioni M, Lacivita E, Leopoldo M.   +23 more
europepmc   +1 more source

Adaptive Hydrogels With Spatiotemporal Stiffening Using pH‐Modulating Enzymes

Advanced Functional Materials, EarlyView.
The chemomechanical coupling in an adaptive hydrogel is studied to further the development of adaptive hydrogels. This coupling is achieved by embedding a pH‐modulating enzyme in a pH‐responsive hydrogel. The enzymatic reaction can be triggered locally, which generates a pH‐decreasing wave throughout the system, increasing the crosslinking density and ...
Natascha Gray, Zoe Grämiger, André R. Studart, Rafael Libanori   +3 more
wiley   +1 more source

A bio-inspired computational pipeline for antibody screening and repurposing. [PDF]

Brief Bioinform
Li J, Ige MA, Zhang C, Liao L, Rasul F, Ren X, Wan X, Chen Y, Zhang H.   +8 more
europepmc   +1 more source

In Vivo Auto-tuning of Antibody-Drug Conjugate Delivery to Maximize Efficacy Using High-Avidity, Low-Affinity Antibodies. [PDF]

Mol Cancer Ther
Kopp A, Dong S, Kwon H, Wang T, Desai AA, Philippart A, Koo DJ, Linderman JJ, Tessier PM, Thurber GM.   +9 more
europepmc   +1 more source

Computational nanobody design using graph neural networks and Metropolis Monte Carlo sampling. [PDF]

Brief Bioinform
Wang L, He X, Qian X, Guo G, Huang Q.
europepmc   +1 more source

Enhancing mutation impact prediction in protein-protein interactions through interpretable graph-based multi-level feature interactions. [PDF]

Bioinformatics
Wu S, Xu N, Xin X, Zhang M, Liu H, Zhu H, Wei Z, Zhao C, Yu L, Feng W.   +9 more
europepmc   +1 more source

Accurate and Generalizable Protein-Ligand Binding Affinity Prediction With Geometric Deep Learning. [PDF]

IEEE Open J Eng Med Biol
Li K, Xiao X, Zhong Z, Yang G.
europepmc   +1 more source

Identifying Insulin Autoantibodies With Differential Risk in Type 1 Diabetes With a Novel Bridging ELISA. [PDF]

Diabetes
Jia X, Zhang C, Waugh K, Miao D, Michels AW, Rewers MJ, Yu L.   +6 more
europepmc   +1 more source