Results 291 to 300 of about 2,265,446 (330)
SMFF-DTA: using a sequential multi-feature fusion method with multiple attention mechanisms to predict drug-target binding affinity. [PDF]
Wang X+6 more
europepmc +1 more source
Sono‐Piezo‐Photosynthesis of Ethylene and Acetylene from Bioethanol under Ambient Conditions
A novel sono‐piezo‐photocatalytic strategy enables the conversion of bioethanol to ethylene (C2H4) and acetylene (C2H2) under ambient conditions, addressing the limitations of conventional methods that are high‐temperature and energy‐intensive. By using an advanced graphene oxide/sodium bismuth titanate heterostructure catalyst, this work achieved ...
Yue Jiang+21 more
wiley +1 more source
hnRNP A1 induces aberrant <i>CFTR</i> exon 9 splicing via a newly discovered ESS element. [PDF]
Beaumont C+7 more
europepmc +1 more source
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim+8 more
wiley +1 more source
Synthesis and Pharmacological Characterization of a Novel Cannabinoid Receptor 1 Antagonist. [PDF]
Bengoetxea de Tena I+13 more
europepmc +1 more source
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
3C protease-independent production of foot-and-mouth disease virus-like particles in Pichia pastoris. [PDF]
Li Z+7 more
europepmc +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan+4 more
wiley +1 more source
Preferential survival of prebiotic metallopeptides in the presence of ultraviolet light. [PDF]
Rossetto D+12 more
europepmc +1 more source