Optimization of Affinity Chromatography Based on Sepharose 4B- chitin for Rapid Purification of Urtica dioica Agglutinin. [PDF]
Iran J Biotechnol, 2023 Heydari M +2 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Small extracellular vesicles (sEVs) are encapsulated into protective shells composed of metal‐phenolic networks (MPNs) and secondary poly(ethylene glycol) layers. This surface modification approach enhances the storage stability of sEVs while maintaining their integrity and functionality. The shells can be selectively disassembled under mild conditions.
Chenyu Wang +8 more
wiley +1 more source
Glutathione affinity chromatography for the scalable purification of an oncolytic virus immunotherapy from microcarrier cell culture. [PDF]
Front Bioeng Biotechnol, 2023 Swartz AR +7 more
europepmc +1 more source
Evolution through time of Pyrrolizidine Alkaloids detection and quantification [PDF]
arXiv, 2013 Pyrrolizidine Alkaloids (PAs) are a group of naturally occurring alkaloids that are produced by plants as a defense mechanism against insect herbivores. The analytical methodologies employed for their detection have come a long way since the first analytical experiment and in the last 30 years had an enormous development, both technological and ...
arxiv
Advanced Healthcare Materials, EarlyView.CLDN18.2 CAR‐T cell‐derived small extracellular vesicles (CAR‐sEVs) display potent cytotoxicity and prolong survival in preclinical pancreatic cancer models. They contain functional CAR proteins and granzyme B, exhibit antigen specificity, and effectively target tumor cells while sparing healthy cells.
Yue Qing +7 more
wiley +1 more source
Adaptation of the binding domain of Lactobacillus acidophilus S-layer protein as a molecular tag for affinity chromatography development. [PDF]
Front Microbiol, 2023 Muruaga EJ +6 more
europepmc +1 more source
Purification of glycolytic enzymes by using affinity-elution chromatography [PDF]
, 1977 R.K. Scopes
openalex +1 more source
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
Analyzing peptides and proteins by mass spectrometry: principles and applications in proteomics [PDF]
, 2012 Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166The study of proteins has been a key element in biomedicine and biotechnology because of their important role in cell functions or enzymatic activity. Cells are the basic unit of living
Estanyol i Ullate, Josep Maria +3 more
core +1 more source
Peak Alignment of Gas Chromatography-Mass Spectrometry Data with Deep Learning [PDF]
arXiv, 2019 We present ChromAlignNet, a deep learning model for alignment of peaks in Gas Chromatography-Mass Spectrometry (GC-MS) data. In GC-MS data, a compound's retention time (RT) may not stay fixed across multiple chromatograms. To use GC-MS data for biomarker discovery requires alignment of identical analyte's RT from different samples.
arxiv