Results 31 to 40 of about 86,698 (268)

The price and affordability of essential medicines, progress and regional distribution in China: a systematic review

Frontiers in Pharmacology, 2023
Background: Essential medicine is a vital component to assure universal access to quality healthcare. However, the trend of affordability to essential medicines in China and its regional differences were not yet fully understood.
Zheng Liu, Zheng Liu, Zheng Liu, Zheng Liu, Zheng Liu, Kun Zou, Kun Zou, Kun Zou, Kun Zou, Dan Liu, Dan Liu, Dan Liu, Dan Liu, Dan Liu, Miao Zhang, Miao Zhang, Miao Zhang, Miao Zhang, Miao Zhang, Yuqing Shi, Yuqing Shi, Yuqing Shi, Yuqing Shi, Yuqing Shi, Zhe Chen, Zhe Chen, Zhe Chen, Zhe Chen, Zhe Chen, Bingchen Lang, Bingchen Lang, Bingchen Lang, Bingchen Lang, Xiao Cheng, Xiao Cheng, Xiao Cheng, Xiao Cheng, Hailong Li, Hailong Li, Hailong Li, Hailong Li, Linan Zeng, Linan Zeng, Linan Zeng, Linan Zeng, Yong Tang, Shaoyang Zhao, Imti Choonara, Yongmu Jiang, Lingli Zhang, Lingli Zhang, Lingli Zhang, Lingli Zhang, Lingli Zhang   +53 more
doaj   +1 more source

Impact of the National Health Insurance Coverage Policy on the Utilisation and Accessibility of Innovative Anti-cancer Medicines in China: An Interrupted Time-Series Study

Frontiers in Public Health, 2021
Objective: The study aimed to evaluate the impact of the National Health Insurance Coverage (NHIC) policy on the utilisation and accessibility of innovative anti-cancer medicines in Nanjing, China.Methods: We used the adjusted World Health Organisation ...
Wenqing Fang, Xinglu Xu, Yulei Zhu, Huizhen Dai, Linlin Shang, Xin Li, Xin Li, Xin Li   +7 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Hybrid Study of Quantitative–Qualitative Analysis to Recognize the Most Cost-Effectiveness Criteria to Develop Affordable Mass Housing

Buildings
Nowadays, providing housing for the low-income groups of society is a concern for governments, especially in developing nations. An attempt has been made to recognize the most significant real criteria for reducing housing project costs and providing ...
Amir Faraji, Tahereh Meydani Haji Agha, Shima Homayoon Arya, Elnaz Ghasemi, Payam Rahnamayiezekavat   +4 more
doaj   +1 more source

Voluntary licensing of long‐acting HIV prevention and treatment regimens: using a proven collaboration‐ and competition‐based mechanism to rapidly expand at‐scale, sustainable, quality‐assured and affordable supplies in LMICs

Journal of the International AIDS Society, 2023
Introduction Emerging long‐acting (LA) prevention and treatment medicines, technologies and regimens could be game‐changing for the HIV response, helping reach the ambitious goal of halting the epidemic by 2030.
Lobna Gaayeb, Aditi Das, Ike James, Rajesh Murthy, Sandra Nobre, Esteban Burrone, Sébastien Morin   +6 more
doaj   +1 more source

Long way to go: Progress of orphan drug accessibility in China from 2017 to 2022

Frontiers in Pharmacology, 2023
Introduction: Over 400 million patients worldwide suffer from rare diseases. Access to orphan drugs is, therefore, crucial for this population. China has been actively working on improving orphan drug accessibility in the past decades, especially since ...
Jia Liu, Yue Yu, Yue Yu, Mingkang Zhong, Mingkang Zhong, Chunlai Ma, Chunlai Ma, Rong Shao   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Doggone affordances: Canine perception of affordances for reaching [PDF]

Psychonomic Bulletin & Review, 2017
Performing any behavior requires perceiving affordances-whether and how that behavior can be performed. Perception of affordances exhibits action scaling-choices about when to transition between two different modes of behavior reflect the fit between action capabilities and environmental properties.
Jeffrey B, Wagman, Matthew D, Langley, Valeri, Farmer-Dougan   +2 more
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A Case for a Eucharistic Approach to Healthcare According to the Social Teachings of the Catholic Church

Religions
The Christian message evokes the motif of abundant life for all. It is a summon to take seriously the holistic approach to life that has meaning and that is relational in all its expressions and manifestations.
SimonMary Asese Aihiokhai
doaj   +1 more source