Results 21 to 30 of about 850 (150)
Diagnostic utility of bleeding assessment tools in congenital fibrinogen deficiencies
Haemophilia, Volume 29, Issue 3, Page 827-835, May 2023., 2023 Abstract Background The assessment of clinical history is crucial before referring a patient for further laboratory testing. Bleeding assessment tools (BAT) are developed to standardize clinical evaluation. A small number of patients with congenital fibrinogen deficiencies (CFDs) have been evaluated with these tools without definitive results.
Samin Mohsenian +8 more
wiley +1 more source
Thrombosis Journal, 2018 Background Patients with congenital afibrinogenemia suffer from spontaneous recurrent severe bleeding. While fibrinogen concentrates are known to effectively treat bleeding episodes, thrombotic complications often occur upon replacement therapy ...
S. Le Quellec +6 more
doaj +1 more source
Haemophilia, Volume 29, Issue 2, Page 423-434, March 2023., 2023 Abstract Introduction Hereditary factor XI (FXI) deficiency is a rare coagulation disorder that may result in excessive bleeding requiring intervention to restore haemostasis. Aim The aim of this review was to report the current knowledge of the worldwide incidence and prevalence of FXI deficiency.
Xinruo Zhang +5 more
wiley +1 more source
Pseudohomozygous dysfibrinogenemia
Research and Practice in Thrombosis and Haemostasis, 2021 Hypodysfibrinogenemia (HD) is a heterogeneous disorder in which plasma fibrinogen antigen and function are both reduced but discordant. This report addresses the key clinical question of whether genetic analysis enables clinically useful ...
Rachel C. Peck +5 more
doaj +1 more source
A Causal Classification System for Intracerebral Hemorrhage Subtypes
Annals of Neurology, Volume 93, Issue 1, Page 16-28, January 2023., 2023 Objective Determining the underlying causes of intracerebral hemorrhage (ICH) is of major importance, because risk factors, prognosis, and management differ by ICH subtype. We developed a new causal CLASsification system for ICH Subtypes, termed CLAS‐ICH, based on recent advances in neuroimaging.
Nicolas Raposo +13 more
wiley +1 more source
Addressing some challenges of congenital fibrinogen disorders in 2023 and beyond
Bleeding, Thrombosis and Vascular Biology, 2023 Congenital fibrinogen disorders (CFD) include several types and subtypes of fibrinogen deficiency, resulting from monoallelic or biallelic mutations in one of the three fibrinogen genes. While it is relatively easy to make an accurate diagnosis based on
Cristina Santoro, Alessandro Casini
doaj +3 more sources
Recurrent myocardial infarction in a case of congenital Afibrinogenemia
Heart Views, 2014 Afibrinogenemia is a rare autosomal recessive bleeding disorder with an estimated prevalence of 1:1,000,000. Usual presentation of this disorder is spontaneous bleeding, bleeding after minor trauma and excessive bleeding during interventional procedures.
Soumya Patra +4 more
doaj +1 more source
Isolated scalp hematoma: An unusual presentation of congenital afibrinogenemia
Indian Pediatrics Case Reports, 2023 Background: Congenital fibrinogen disorder is a rare autosomal recessive blood coagulation disorder, where majority of patients present with bleeding, whereas a few may paradoxically develop thrombosis.
Arnab Ghorui +2 more
doaj +1 more source
Congenital Afibrinogenemia presenting as antenatal intracranial bleed: a case report
Italian Journal of Pediatrics, 2010 Congenital afibrinogenemia is a very rare inherited coagulation disorder, characterized by virtual absence of plasma fibrinogen (factor I). There are only about 250 cases reported in the world literature 1.
Parapurath Rajiv +2 more
doaj +1 more source
Pregnancy outcome in afibrinogenemia: Are we giving enough fibrinogen concentrate? A case series
Research and Practice in Thrombosis and Haemostasis, 2020 Congenital afibrinogenemia is a rare autosomal recessive disorder associated with an increased risk of hemorrhage, thrombosis, and obstetric complications. This case series of 4 pregnancies in 2 related patients seeks to address the key clinical question
Joline L. Saes +3 more
doaj +1 more source