Results 21 to 30 of about 1,319 (189)

Afibrinogenemia following snake bite (Crotalus durissus terrificus) [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 1988
This paper reports two cases of afibrinogenemia with normal platelet count following Crotalus durissus terrificus, snake bite Both patients presented high output acute renal failure and case two also had increased blood levels of CPK and LDH compatible ...
C. F. S. Amaral, N. A. Rezende, T. M. G. Pedrosa, O. A. da Silva, E. R. P. Pedroso   +4 more
doaj   +3 more sources

The β-Chain Mutation p.Arg17Stop Impairs Fibrinogen Synthesis and Secretion: A Nonsense Mutation Associated With Hypofibrinogenemia. [PDF]

J Clin Lab Anal
We reported the first case of a FGB p.Arg17Stop mutation with a heterozygous gene status, and conducted research on the pathogenic mechanisms related to the fibrinogen Bβ (p.Arg17Stop) mutation. This mutation significantly impairs both the synthesis and secretion of fibrinogen.
Qian C, Huang C, Luo Q, Qin K, Wu Y, Liao L, Zhang Q, Xiang L, Yan J.   +8 more
europepmc   +2 more sources

The Swiss Haemophilia Registry-Report From the First 8 Years. [PDF]

Haemophilia
ABSTRACT Introduction Patient registries capture disease related information and provide a valuable source for real‐world data on rare diseases and their management. The Swiss Haemophilia Registry (SHR) was established in 2015 on the basis of a new Swiss federal human research act.
Bosch A, Alberio L, Fontana P, Graf L, Hovinga JAK, Weid NV, Rizzi M, Albisetti M, Swiss Haemophilia Network.   +8 more
europepmc   +2 more sources

Correction to "A Case of Congenital Afibrinogenemia With Multiple Thrombotic and Hemorrhagic Disorders". [PDF]

Clin Case Rep
Clinical Case Reports, Volume 12, Issue 11, November 2024.
europepmc   +2 more sources

PB2654: RARE BLEEDING DISORDERS: LONG-TERM EXPERIENCE FROM A HEMOPHILIA CENTER [PDF]

Hemasphere, 2023
HemaSphere, Volume 7, Issue S3, August 2023.
Meimaridis A, Chissan S, Kotsiou N, Gavriilaki E, Moka E, Vakalopoulou S.   +5 more
europepmc   +2 more sources

Afibrinogenemia: A rare cause of refractory puberty menorrhagia

Iraqi Journal of Hematology, 2022
Excessive menstruation after attaining menarche during adolescent age group is known as puberty menorrhagia (PM). The most common presentation includes anemia due to excessive blood loss.
Vandana Kamatham, Vijayan Sharmila, Thirunavukkarasu Arun Babu   +2 more
doaj   +1 more source

Real‐World Experience with a Human Fibrinogen Concentrate: Clinical Data from Adult and Pediatric Patients Requiring Fibrinogen for Bleeding Control and Prevention

The Journal of Clinical Pharmacology, Volume 63, Issue 11, Page 1186-1196, November 2023., 2023
Abstract Human fibrinogen concentrate (Fibryga) received temporary approval for fibrinogen replacement therapy in France (2017), with subsequent full approval for congenital and acquired hypofibrinogenemia. We evaluated real‐world use for on‐demand treatment of bleeding and prophylaxis to enhance our knowledge on fibrinogen concentrate as an option for
Francois Stéphan, Loriane Gutermann, Stéphanie Bourget, Sarah Djabarouti, Johanna Berdugo, Yann Fardini, Pierre Clerson, Guillaume Hébert, Chafké Belmokhtar   +8 more
wiley   +1 more source

Congenital fibrinogen disorders: Strengthening genotype–phenotype correlations through novel genetic diagnostic tools

British Journal of Haematology, Volume 203, Issue 3, Page 355-368, November 2023., 2023
Summary Congenital fibrinogen disorders or CFDs are heterogenous, both in clinical manifestation and array of culprit molecular lesions. Correlations between phenotype and genotype remain poorly defined. This review examines the genetic landscape discovered to date for this rare condition.
Radha Ramanan, James D. McFadyen, Andrew C. Perkins, Huyen A. Tran   +3 more
wiley   +1 more source

Comparison of coagulation parameters associated with fibrinogen concentrate and cryoprecipitate for treatment of bleeding in patients undergoing cytoreductive surgery for pseudomyxoma peritonei: Subanalysis from a randomized, controlled phase 2 study

Health Science Reports, Volume 6, Issue 9, September 2023., 2023
Abstract Background and Aims The FORMA‐05 study compared the efficacy and safety of human fibrinogen concentrate (HFC) versus cryoprecipitate for hemostasis in bleeding patients undergoing cytoreductive surgery for pseudomyxoma peritonei (PMP). This subanalysis explores coagulation parameters in the FORMA‐05 patients, with a focus on the seven patients
Ashok Roy, Nigel Sargant, John Bell, Sophia Stanford, Cristina Solomon, Irina Kruzhkova, Sigurd Knaub, Faheez Mohamed   +7 more
wiley   +1 more source

The role of new inflammatory markers in determining disease activation and severity in patients with hidradenitis suppurativa

International Journal of Dermatology, Volume 62, Issue 8, Page 1076-1081, August 2023., 2023
Abstract Hidradenitis suppurativa (HS) is a chronic inflammatory disease. Recently published studies have suggested the use of markers of inflammation to monitor HS patients. These studies discuss the platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR), pan‐immune‐inflammation value (PIV), and systemic immune‐inflammation index (SIII ...
Eda Öksüm Solak, Burcu Baran Ketencioglu, Salih L. Cinar, Demet Kartal, Murat Borlu   +4 more
wiley   +1 more source