Results 51 to 60 of about 2,449 (204)
Thrombosis Journal, 2018 Background Patients with congenital afibrinogenemia suffer from spontaneous recurrent severe bleeding. While fibrinogen concentrates are known to effectively treat bleeding episodes, thrombotic complications often occur upon replacement therapy ...
S. Le Quellec +6 more
doaj +1 more source
Haemophilia, Volume 29, Issue 2, Page 423-434, March 2023., 2023 Abstract Introduction Hereditary factor XI (FXI) deficiency is a rare coagulation disorder that may result in excessive bleeding requiring intervention to restore haemostasis. Aim The aim of this review was to report the current knowledge of the worldwide incidence and prevalence of FXI deficiency.
Xinruo Zhang +5 more
wiley +1 more source
Pseudohomozygous dysfibrinogenemia
Research and Practice in Thrombosis and Haemostasis, 2021 Hypodysfibrinogenemia (HD) is a heterogeneous disorder in which plasma fibrinogen antigen and function are both reduced but discordant. This report addresses the key clinical question of whether genetic analysis enables clinically useful ...
Rachel C. Peck +5 more
doaj +1 more source
Blood, 2021 Due to its low prevalence, epidemiologic data on afibrinogenemia are limited and none are available on health-related quality of life (HRQoL). We conducted a cross-sectional international study to characterize the clinical features, the fibrinogen ...
A. Casini +14 more
semanticscholar +1 more source
A Causal Classification System for Intracerebral Hemorrhage Subtypes
Annals of Neurology, Volume 93, Issue 1, Page 16-28, January 2023., 2023 Objective Determining the underlying causes of intracerebral hemorrhage (ICH) is of major importance, because risk factors, prognosis, and management differ by ICH subtype. We developed a new causal CLASsification system for ICH Subtypes, termed CLAS‐ICH, based on recent advances in neuroimaging.
Nicolas Raposo +13 more
wiley +1 more source
Addressing some challenges of congenital fibrinogen disorders in 2023 and beyond
Bleeding, Thrombosis and Vascular Biology, 2023 Congenital fibrinogen disorders (CFD) include several types and subtypes of fibrinogen deficiency, resulting from monoallelic or biallelic mutations in one of the three fibrinogen genes. While it is relatively easy to make an accurate diagnosis based on
Cristina Santoro, Alessandro Casini
doaj +3 more sources
Recurrent myocardial infarction in a case of congenital Afibrinogenemia
Heart Views, 2014 Afibrinogenemia is a rare autosomal recessive bleeding disorder with an estimated prevalence of 1:1,000,000. Usual presentation of this disorder is spontaneous bleeding, bleeding after minor trauma and excessive bleeding during interventional procedures.
Soumya Patra +4 more
doaj +1 more source
Congenital Afibrinogenemia presenting as antenatal intracranial bleed: a case report
Italian Journal of Pediatrics, 2010 Congenital afibrinogenemia is a very rare inherited coagulation disorder, characterized by virtual absence of plasma fibrinogen (factor I). There are only about 250 cases reported in the world literature 1.
Parapurath Rajiv +2 more
doaj +1 more source
Indian Journal of Anaesthesia, 2011 Congenital afibrinogenemia is a very rare autosomal recessive disorder, results from mutation that affects plasma fibrinogen concentration. It is frequently associated with bleeding diathesis of varying severity.
Sham Sunder Goyal +3 more
doaj +1 more source
Acta Médica Portuguesa, 1998 The authors present a case of congenital afibrinogenemia. A review of the literature is made, and some aspects of this rare inherited coagulation disorder are suggested and commented on.
P Pastilha +7 more
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