Results 121 to 130 of about 42,083 (246)

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 313-323, August 2026.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory, Gonzalo Villapalos Garcia, Dora Koller, Solomon Adams, Chad A. Bousman, Evangelia Eirini Tsermpini, Michelle Whirl‐Carrillo, Amy J. Turner, Volker M. Lauschke, Mohamed Nagy, Erin C. Boone, Teri E. Klein, Pablo Zubiaur, Andrea Gaedigk   +13 more
wiley   +1 more source

Thermolysed and active yeast to reduce the toxicity of aflatoxin

Scientia Agricola, 2002
Aflatoxins are hepatotoxic metabolites produced by Aspergillus flavus and A. parasiticus on a number of agricultural commodities. This research was carried out to evaluate the ability of thermolysed and active Saccharomyces cerevisiae to attenuate liver ...
Antonio Sampaio Baptista, Jorge Horii, Maria Antonia Calori-Domingues, Eduardo Micotti da Glória, Jocelem Mastrodi Salgado, Mário Roberto Vizioli   +5 more
doaj  

Micro‐ and Nanostructured Materials in Edible Coatings for the Preservation of Fruits and Vegetables

eFood, Volume 7, Issue 4, August 2026.
Graphical representation of micro‐ and nanostructured materials in edible coatings for the preservation of fruits and vegetables. ABSTRACT Edible coatings based on advanced nanostructured materials have emerged as effective strategies for extending the shelf life and maintaining the quality of fresh fruits and vegetables.
Carlos Méndez‐Durazno, Katherine Vaca‐Escobar, Fernanda Landeta‐Constante, Santiago Guerrero‐Jaramillo, Milton Villacís‐García, Patricio J. Espinoza‐Montero   +5 more
wiley   +1 more source

Hepatocellular carcinoma and aflatoxin in Sudan: The way forward [PDF]

Hepatocellular carcinoma (HCC) is the sixth most common type of cancer and the third leading cause of death worldwide. It is especially prevalent in developing countries, with around 80% of cases occurring in Asia and Africa.
Moawia Mohammed Ali Elhassan
core   +2 more sources

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, Volume 46, Issue 8, Page 2599-2622, August 2026.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

Reconsidering Molecular Docking Practices in Aptamer Research

ChemBioChem, Volume 27, Issue 14, 29 July 2026.
Benchmarking against the theophylline aptamer crystal structure shows that current docking workflows generate incorrect structures and fail to predict binding specificity, underscoring the need for caution when interpreting docking results in aptamer research. Molecular docking is increasingly used to infer aptamer–target interactions, yet most studies
Yachen Xie, Juewen Liu
wiley   +1 more source

The development of immunoassays for the detection of bovine brucellosis and aflatoxin B1 [PDF]

, 2004
The research discussed in this thesis focuses on the development and characterisation of immunoassays for the detection of aflatoxin Bi (AFBi), a toxic fungal metabolite, and for the diagnosis of bovine brucellosis, a highly contagious disease of cattle ...
Dunne, Lynsey
core  

Evaluation of aflatoxin B1 in different parts of pistachio fruit and effects of processing stages [PDF]

Bihdāsht-i Mavādd-i Ghaz̠āyī, 2014
Pistachio nut as the most important agricultural export products is facing challenges trough production and conception. Toxigenic Aspergillus species are able to grow and produce dangerous mycotoxins on pistachio nut.
R Dargahi, H Masoumi, M Moradi, S.R Fani
doaj  

Development of immunosensors for mycotoxins analysis [PDF]

, 2010
Aflatoxin B₁ (AFB₁) and fumonisins (Fms) are mycotoxin contaminants found in peanuts and corn, respectively, and are known to be immunosuppressive and carcinogenic compounds.
Abdul Kadir, Mohamad Kamal.
core  

Research progress on hazards of aflatoxin to livestock and poultry breeding and microbial detoxification

Siliao yanjiu
Aflatoxin is a highly toxic mycotoxin. When feed raw materials are contaminated with aflatoxin, it will harm the health of livestock and poultry, such as causing liver and spleen diseases, gastrointestinal dysfunction, impaired kidney metabolism and ...
QI Kaixuan, ZHANG Mengyu, MA Tenghe, FU Guanhua, WANG Lihong   +4 more
doaj