The widespread fungal toxin Aflatoxin B1 (AFB1) is an inevitable pollutant affecting the health of humans, poultry, and livestock. Although studies indicate that AFB1 is hepatotoxic, there are few studies on AFB1-induced hepatotoxicity in sheep.
Yuzhen Sui +9 more
doaj +1 more source
The production of aflatoxin B1 or G1 by Aspergillus parasiticus at various combinations of temperature and water activity is related to the ratio of aflS to aflR expression [PDF]
The influence of varying combinations of wateractivity (aw) and temperature on growth, aflatoxin biosynthesisand aflR/aflS expression of Aspergillus parasiticuswas analysed in the ranges 17-42°C and 0.90-0.99 aw.Optimum growth was at 35°C.
Rüfer, C. E. +12 more
core +1 more source
Control of Aflatoxin Production of Aspergillus flavus and Aspergillus parasiticus Using RNA Silencing Technology by Targeting aflD (nor-1) Gene. [PDF]
Aspergillus flavus and Aspergillus parasiticus are important pathogens of cotton, corn, peanuts and other oil-seed crops, producing toxins both in the field and during storage.
Daniel Caley +14 more
core +1 more source
Aflatoxicosis in a canine associated with consumption of contaminated food - case report [PDF]
Aflatoxins are mycotoxins produced by fungi that cause severe poisoning, mainly affecting the liver. Aflatoxicosis is rarely reported in dogs, but this species is extremely sensitive.
M.D. Furquim +4 more
doaj +1 more source
Aflatoxins can cause intoxication and poisoning in animals and humans. Among these molecules, aflatoxin B1 (AFB1) is the most dangerous because of its carcinogenic and mutagenic properties. To mitigate these effects, clay adsorbents are commonly included
Sara Paola Hernández-Martínez +6 more
doaj +1 more source
Influence of aflatoxin B1 on mRNA levels of acute-phase proteins and oncoproteins in albino rat liver [PDF]
Background: The effect of aflatoxin B1 (AFB1) administration on expression of genes coding for acute-phase proteins, and nuclear protooncogenes c-fos and c-jun, and alpha-fetoprotein gene has been studied in rats.
Krtolica Koviljka V. +3 more
doaj +1 more source
New Insights Into the Persistent Effects of Acute Exposure to AFB1 on Rat Liver
Aflatoxin B1 (AFB1) has mutagenesis, carcinogenesis and teratogenesis effects and mainly found in food crops and their processed foods. AFB1 exposure can cause acute or chronic liver poisoning, but there were few studies on the persistent effects of ...
Jiahui Yan +10 more
doaj +1 more source
Aflatoxin exposure and viral hepatitis in the etiology of liver cirrhosis in the Gambia, West Africa. [PDF]
BACKGROUND: Cirrhosis of the liver is thought to be a major cause of morbidity and mortality in sub-Saharan Africa, but few controlled studies on the etiology of cirrhosis have been conducted in this region.
James J. Goedert +21 more
core +1 more source
Research Progress on Aflatoxin Inhibitors and Their Mechanisms of Action
Aflatoxins (AF) are secondary metabolites produced by fungi such as Aspergillus flavus, A. parasiticus, and other related species, possessing strong carcinogenic and toxic properties.
Shaowen WU +3 more
doaj +1 more source
The graphical abstract illustrates the interconnected relationship between food safety management, mycotoxin toxicity, and detoxification strategies, highlighting how preventive measures across the food chain can minimize mycotoxin contamination and reduce adverse health effects in humans/animals.
Chinaza Godswill Awuchi
wiley +1 more source

