Results 41 to 50 of about 380,121 (293)

Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy

Nature Communications, 2017
CRISPR RNA-guided endonuclease Cas9 recognizes and cleaves the double-stranded DNA complementary to the RNA guide. Here the authors use high-speed atomic force micropcopy (HS-AFM) to visualize the conformational dynamics of Cas9 during its DNA targeting ...
Mikihiro Shibata, Hiroshi Nishimasu, Noriyuki Kodera, Seiichi Hirano, Toshio Ando, Takayuki Uchihashi, Osamu Nureki   +6 more
doaj   +1 more source

ARMScope – the versatile platform for scanning probe microscopy systems

Metrology and Measurement Systems, 2020
Scanning probe microscopy (SPM) since its invention in the 80’s became very popular in examination of many different sample parameters, both in university and industry. This was the effect of bringing this technology closer to the operator.
Świadkowski Bartosz, Piasecki Tomasz, Rudek Maciej, Świątkowski Michał, Gajewski Krzysztof, Majstrzyk Wojciech, Babij Michał, Dzierka Andrzej, Gotszalk Teodor   +8 more
doaj   +1 more source

Experimental Evaluation of 100Cr6 Steel Microindented Surfaces Under Lubricated Nonconformal Point Contacts

Advanced Engineering Materials, EarlyView.
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi, Pasquale Guglielmi, Gianfranco Palumbo, Giuseppe Carbone   +3 more
wiley   +1 more source

Spin-polarized Current-induced Instability in Spin-Valve with Antiferromagnetic Layer

, 2007
In the framework of phenomenological model we consider dynamics of a compensated collinear antiferromagnet (AFM) in the presence of spin-polarised current.
Gomonay, H., Loktev, V.
core   +1 more source

Elinvar Materials: Recent Progress and Challenges

Advanced Engineering Materials, EarlyView.
Elinvar materials, exhibiting temperature‐invariant elastic modulus, are critical for precision instruments and emerging technologies. This article reviews recent progress in the field, with a focus on the anomalous thermoelastic behavior observed in key material systems.
Wenjie Li, Yang Ren
wiley   +1 more source

Hoe ziet de accountancysector eruit in 2050? AFM en stakeholders in gesprek [PDF]

MAB
De AFM is gestart met een project ‘visie 2050’ om een dialoog te stimuleren over hoe de accountancysector er in 2050 uit zou kunnen zien. Verdergaande digitalisering en AI, assurance op duurzaamheidsrapportering, de krappe arbeidsmarkt, veel meer en ook ...
Marine Fees, Barbara Majoor, Annemarie Oord   +2 more
doaj   +3 more sources

Removing Oxide Layers and Retaining Oxide‐Free Steel Surfaces by Polishing in Oxygen‐Free Atmosphere

Advanced Engineering Materials, EarlyView.
In this study, the efficacy of wet mechanical polishing under an oxygen‐free atmosphere for deoxidation and the retention of an oxide‐free steel surface are elucidated using X‐ray photoelectron spectroscopy. The methodology proved successful; however, the results were highly dependent on the preparation of the solvents used to clean the samples after ...
Friedrich Bürger, Lienhard Wegewitz, Wolfgang Maus‐Friedrichs   +2 more
wiley   +1 more source

Pharmacological modulation of developmental and synaptic phenotypes in human SHANK3 deficient stem cell-derived neuronal models

Translational Psychiatry
Phelan-McDermid syndrome (PMDS) arises from mutations in the terminal region of chromosome 22q13, impacting the SHANK3 gene. The resulting deficiency of the postsynaptic density scaffolding protein SHANK3 is associated with autism spectrum disorder (ASD).
Amandine Thibaudeau, Karen Schmitt, Louise François, Laure Chatrousse, David Hoffmann, Loic Cousin, Amélie Weiss, Aurore Vuidel, Christina B. Jacob, Peter Sommer, Alexandra Benchoua, Johannes H. Wilbertz   +11 more
doaj   +1 more source

Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA

Cell Reports, 2012
One puzzling observation in patients affected with Hutchinson-Gilford progeria syndrome (HGPS), who overall exhibit systemic and dramatic premature aging, is the absence of any conspicuous cognitive impairment. Recent studies based on induced pluripotent
Xavier Nissan, Sophie Blondel, Claire Navarro, Yves Maury, Cécile Denis, Mathilde Girard, Cécile Martinat, Annachiara De Sandre-Giovannoli, Nicolas Levy, Marc Peschanski   +9 more
doaj   +1 more source

Antiferromagnetic Phases in the Fulde-Ferrell-Larkin-Ovchinnikov State of CeCoIn_5

, 2011
The antiferromagnetic (AFM) order in the Fulde-Ferrell-Larkin-Ovchinnikov (FFLO) superconducting state is analyzed on the basis of a Ginzburg-Landau theory.
Adachi H., Agterberg D. F., Aperis A., Aperis A., Bianchi A., Bianchi A., Capan C., Casalbuoni R., Correa V. F., Fulde P., Ikeda R., Ikeda R., Ikeda R., Kenzelmann M., Kenzelmann M., Kitaoka Y., Koutroulakis G., Koutroulakis G., Larkin A. I., Lortz R., Martin C., Matsuda Y., Miclea C. F., Mitrović V. F., Miyake K., Partridge G. B., Radovan H. A., Ronning F., Shinagawa J., Singleton J., Uji S., Watanabe T., Yanase Y., Yanase Y., Yanase Y., Young B.-L., Zwierlein M. W.   +36 more
core   +1 more source