Combination of Plasma Pharmacochemistry, RNA-Seq, and Molecular Docking Strategies to Reveal the Mechanism of the Alkaloid Fraction of Nelumbinis folium for the Treatment of Hyperlipidemia [PDF]
MoleculesNelumbinis folium (N. folium) exhibits hypolipidemic effects and shows great potential for application in lipid-lowering drugs and healthcare products.
Yuan Cai +8 more
doaj +2 more sources
Biomineralized apoferritin nanoparticles delivering dihydroartemisinin and calcium for synergistic breast cancer therapy [PDF]
Scientific ReportsBreast cancer is one of the most common gynecological malignancies and poses a severe health risk to women. In recent years, ferroptosis therapy has been considered a promising therapeutic strategy for breast cancer by promoting intracellular reactive ...
Shanshan Zhao, Peng Liu, Yan Li
doaj +2 more sources
Prolonged dysregulation of gene expression and biomarkers of coagulation, fibrinolysis, and endothelium in pediatric central nervous system malaria [PDF]
BMC Infectious DiseasesBackground Children with central nervous system malaria (CNS-M) have gene expression profiles and plasma biomarkers of malaria pathogenesis that differ from children with uncomplicated malaria (UM, malaria infection with fever and no systemic organ ...
Arlene E. Dent +12 more
doaj +2 more sources
High efficacy of huCD20-targeted AcTaferon in humanized patient derived xenograft models of aggressive B cell lymphoma [PDF]
Experimental Hematology & OncologyType I interferon (IFN) is a potent antitumoral drug, with an important history in the treatment of hematologic malignancies. However, its pleiotropic nature leads to severe dose-limiting toxicities that blunt its therapeutic potential.
Willem Daneels +13 more
doaj +2 more sources
An attenuation field network for dedicated cone beam breast CT with short scan and offset detector geometry [PDF]
Scientific ReportsThe feasibility of full-scan, offset-detector geometry cone-beam CT has been demonstrated for several clinical applications. For full-scan acquisition with offset-detector geometry, data redundancy from complementary views can be exploited during image ...
Zhiyang Fu +2 more
doaj +2 more sources
Effect of anterior femoral cortical notch grade on postoperative function and complications during TKA surgery: A multicenter, retrospective study [PDF]
Open MedicineTo explore the effect of AFN on knee function and complications in patients after TKA.
Jin Zhaokai +10 more
doaj +2 more sources
Discovery of Brominated Alboflavusins With Anti-MRSA Activities
Frontiers in Microbiology, 2021 As methicillin-resistant Staphylococcus aureus (MRSA) is becoming a serious pathogenic threaten to human health worldwide, there is an urgent need to discover new antibiotics for the treatment of MRSA infections.
Chao Li +8 more
doaj +1 more source
Overheating assessment in Passivhaus dwellings: the influence of prediction tools
Buildings & Cities, 2022 Thermal comfort during the summer in the Passivhaus concept relies mainly on natural ventilation to provide indoor cooling. Do airflow modeling tools accurately predict overheating in summer and for anticipated warmer climates?
Vitor Leite Goncalves +3 more
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L'AEROFOTOTECA NAZIONALE RACCONTA… l'Italia dal cielo, tra Guerra fredda e boom economico
GEOmedia, 2019 Tra i numerosi fondi che costituiscono l'immenso patrimonio di immagini aeree conservato in Aerofototeca Nazionale (AFN), uno dei meno noti al grande pubblico è quello formato dalle riprese aerofotogrammetriche con negativi in formato 9x9 pollici (cm ...
Francesca Pompilio
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Response Surface Methodology for Boron Removal by Donnan Dialysis: Doehlert Experimental Design
Membranes, 2021 The removal of boron by Donnan dialysis from aqueous solutions has been studied according to response surface methodology (RSM). First, a preliminary study was performed with two membranes (AFN and ACS) in order to determine the experimental field based ...
Ikhlass Marzouk Trifi +4 more
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