Results 121 to 130 of about 674 (144)
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Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2021
Afoxolaner is a new insecticidal and acaricidal active pharmaceutical ingredient (API) belonging to the isoxazoline family, widely prescribed for the control of fleas and ticks in dogs. A stability-indicating reversed-phase high performance liquid chromatography (RP-HPLC) method has been developed for the assay of afoxolaner and determination of its ...
Sarju Adhikari, Abu M Rustum
exaly +3 more sources
Afoxolaner is a new insecticidal and acaricidal active pharmaceutical ingredient (API) belonging to the isoxazoline family, widely prescribed for the control of fleas and ticks in dogs. A stability-indicating reversed-phase high performance liquid chromatography (RP-HPLC) method has been developed for the assay of afoxolaner and determination of its ...
Sarju Adhikari, Abu M Rustum
exaly +3 more sources
Efficacy of Afoxolaner Against Dermacentor variabilis Ticks in Dogs
Veterinary Parasitology, 2014 Efficacy of afoxolaner, a novel isoxazoline insecticide/acaricide, against Dermacentor variabilis ticks was confirmed in two laboratory studies. Each study utilized a controlled, randomized block design. One day prior to treatment, beagle dogs were infested with 50 unfed adult ticks. Repeat infestations were performed weekly for four weeks.
Diane Larsen
exaly +3 more sources
Safety Evaluation of Orally Administered Afoxolaner in 8-Week-Old Dogs
Veterinary Parasitology, 2014 The safety profile of afoxolaner, a new isoxazoline molecule, was evaluated following the regulatory requirements when administered six times orally in a soft chewable formulation at a dose of at least 1×, 3× or 5× the maximum exposure dose (6.3mg/kg) in 8-week-old Beagle dogs.
Diane Larsen
exaly +3 more sources
Veterinary Parasitology, 2014 Two studies were conducted to confirm that a single oral dose of the novel insecticide/acaricide afoxolaner is efficacious against existing infestations of Rhipicephalus sanguineus sensu lato in dogs and can control re-infestation for up to 35 days. Each study utilized 16 purpose bred adult dogs using a controlled randomized block design.
Pascal Dumont, Diane Larsen
exaly +3 more sources
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2021
Sarcoptic mange is a pruritic, contagious, ectoparasitic skin disease that affects mammals, including the domestic dog. The objective of this study was to evaluate and compare the efficacy of afoxolaner plus milbemycin oxime (NexGard Spectra) and afoxolaner alone (NexGard) as treatments for sarcoptic mange in naturally infested dogs.
Camilo, Romero-Núñez +5 more
openaire +1 more source
Sarcoptic mange is a pruritic, contagious, ectoparasitic skin disease that affects mammals, including the domestic dog. The objective of this study was to evaluate and compare the efficacy of afoxolaner plus milbemycin oxime (NexGard Spectra) and afoxolaner alone (NexGard) as treatments for sarcoptic mange in naturally infested dogs.
Camilo, Romero-Núñez +5 more
openaire +1 more source
Veterinary Parasitology, 2014 The pharmacokinetics of afoxolaner in dogs was evaluated following either intravenous or after oral administration of NEXGARD(®), a soft chewable formulation. Afoxolaner is a member of one of the newest classes of antiparasitic agents, known as antiparasitic isoxazolines.
Letendre, Laura +5 more
exaly +3 more sources
Veterinary Parasitology
Otodectes cynotis, commonly known as "the ear mite," is a highly contagious ectoparasite and a significant cause of otitis externa in canines. The objective of the current study was to determine the efficacy of the isoxazoline afoxolaner (Nexgard®), and the combination of afoxolaner with milbemycin oxime (Nexgard Spectra®), in dogs naturally infested ...
Maxime Madder +2 more
exaly +3 more sources
Otodectes cynotis, commonly known as "the ear mite," is a highly contagious ectoparasite and a significant cause of otitis externa in canines. The objective of the current study was to determine the efficacy of the isoxazoline afoxolaner (Nexgard®), and the combination of afoxolaner with milbemycin oxime (Nexgard Spectra®), in dogs naturally infested ...
Maxime Madder +2 more
exaly +3 more sources
Efficacy of afoxolaner in the treatment of otodectic mange in naturally infested cats
Veterinary Parasitology, 2018Afoxolaner is a drug belonging to the isoxazolines' family, and it is recommended for ectoparasite control in dogs. The objective of this study was to evaluate the efficacy of afoxolaner in the treatment of otodectic mange in naturally infested cats. Sixteen cats were divided into two groups (treated and control).
Marília Alves, Machado +7 more
openaire +2 more sources
Veterinary Parasitology, 2014 The efficacy of orally administered afoxolaner against adult dog fleas, Ctenocephalides canis, was evaluated in a controlled, blinded study. A total of 32 dogs were infested with 100 adult unfed fleas approximately 24h prior to treatment and then at weekly intervals for 5 weeks after treatment.
Pascal Dumont
exaly +3 more sources
Veterinary Dermatology, 2018
BackgroundEctoparasitism of ornamental birds, including captive species kept in zoos, represents a serious health problem. Up to 13 different species of lice have been reported to affect peacocks worldwide and heavy infestation may cause anaemia. Because of this, alternatives to the prevailing treatments have been sought including use of isoxazolines ...
Enrique Yarto Jaramillo +5 more
openaire +2 more sources
BackgroundEctoparasitism of ornamental birds, including captive species kept in zoos, represents a serious health problem. Up to 13 different species of lice have been reported to affect peacocks worldwide and heavy infestation may cause anaemia. Because of this, alternatives to the prevailing treatments have been sought including use of isoxazolines ...
Enrique Yarto Jaramillo +5 more
openaire +2 more sources