Results 41 to 50 of about 674 (144)

Dog owner flea/tick medication purchases in the USA

Parasites & Vectors, 2018
Background Veterinary clinic transaction records from the USA were examined to determine dog owner purchase patterns for three prescription ectoparasiticides.
Robert Lavan, Rob Armstrong, Kaan Tunceli, Dorothy Normile   +3 more
doaj   +2 more sources

Interaction of Afoxolaner with Nematode GABA Receptors, Potential for Repurposing and Development of New Anthelmintics

Background/Objectives: Drug repurposing is one of the possible sources of new anthelmintics. Afoxolaner is a insecticide/acaricide that acts on the insect GABA receptor and regulates uptake of chloride ions. We examined the interaction of afoxolaner with GABA receptors of nematodes.
Dragana Medić, Đorđe S. Marjanović, Tihomir Marić, Vladimir Marjanović, Stamen Radulović, Jelena Nedeljković Trailović, Siniša Grozdanić, Strahinja Stevanović, Saša M. Trailović   +8 more
openaire   +2 more sources

Evaluation of the effect of afoxalaner with milbemycin 1 oxime in the treatment of rabbits naturally infected with Psoroptes cuniculi.

PLoS ONE, 2020
Rabbits (Oryctolagus cuniculi) are very popular as pets. However, problems of otitits caused by Psoroptes cuniculi are one of the main reasons to visit the veterinarian.
Camilo Romero Núñez, Ariadna Flores Ortega, Galia Sheinberg Waisburd, Alberto Martin Cordero, Enrique Yarto Jaramillo, Rafael Heredia Cárdenas, Linda G Bautista Gómez   +6 more
doaj   +2 more sources

Prevention of the transmission of Babesia rossi by Haemaphysalis elliptica in dogs treated with Nexgard®

Parasite, 2019
This experimental study aimed to determine the efficacy of Afoxolaner (NexGard®) to prevent Babesia rossi transmission by Haemaphysalis elliptica ticks on dogs. The study included three groups of seven dogs each.
Beugnet Frederic, Lebon Wilfried, de Vos Christa   +2 more
doaj   +2 more sources

The ability of an oral formulation of afoxolaner to block the transmission of Babesia canis by Dermacentor reticulatus ticks to dogs [PDF]

Parasites & Vectors, 2014
Background Canine babesiosis due to Babesia canis is an endemic disease in many European countries. A vaccine is available in some countries, but it does not prevent the infection and just helps in reducing the gravity of clinical signs.
Frederic Beugnet, Lenaig Halos, Diane Larsen, Michel Labuschagné, Heidi Erasmus, Josephus Fourie   +5 more
doaj   +3 more sources

Neglected but Not Harmless: Characterising Nonantibiotic Antimicrobial Use in Small Animal Practices in Colombia. [PDF]

Vet Med Sci
Widely used but poorly documented, nonantibiotic antimicrobials represent an overlooked gap in veterinary practice. Frequent prescribing alongside suboptimal dosing and incomplete records underscores the need to formally include NAAs in antimicrobial stewardship and One Health surveillance efforts.
Correa-Valencia NM, Arango-Arcila S, Mendoza NK, Sierra-Zapata DA, Guzmán-Mejía VA, Carmona Ramírez A, Restrepo Salazar JG.   +6 more
europepmc   +2 more sources

Functional Characterization of the Cat and Dog Wild-Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany. [PDF]

J Vet Pharmacol Ther
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Siegl L, Bethäuser M, Nürnberger D, Oswald S, Moritz A, Hamann M, Geyer J.   +6 more
europepmc   +2 more sources

Safety of Oral Afoxolaner Formulated With or Without Milbemycin Oxime in Homozygous MDR1-Deficient Collie Dogs [PDF]

Journal of Veterinary Pharmacology and Therapeutics, 2022
Eric Tielemans
exaly   +2 more sources

Efficacy of a chewable tablet containing sarolaner, moxidectin and pyrantel for the treatment of generalised demodicosis in dogs. [PDF]

Vet Dermatol
Background – Demodicosis is common in dogs and is caused by proliferation of commensal Demodex canis mites. Objective – To evaluate the efficacy of sarolaner in combination with moxidectin and pyrantel (SMP) for the treatment of generalised demodicosis in dogs.
Becskei C, Liebenberg J, Fernandes T, Borowski S, D'Hanis L, Mahabir SP.   +5 more
europepmc   +2 more sources

Centripetal Axonal Transport as a Gateway to the CNS for Veterinary Antiparasitics: Bypassing the Blood-Brain Barrier, Clinical Impact in Vulnerable Age Groups, and the Potential Facilitating Role of PFAS. [PDF]

J Toxicol
The widespread use of veterinary antiparasitics, including neonicotinoids, isoxazolines, avermectins, and pyrethroids, is essential for canine health but raises concerns regarding potential neurotoxicity, particularly in young and geriatric animals.
Britti D, Marabelli R, Calzetta L.
europepmc   +2 more sources