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Alpha-Fetoprotein (AFP) biosensors

Clinica Chimica Acta
Alpha-fetoprotein (AFP) is a glycoprotein mainly produced during fetal development, and elevated levels in adults are frequently associated with liver diseases, especially hepatocellular carcinoma (HCC), as well as certain germ cell tumors. Measuring AFP in biological samples is crucial for early diagnosis, monitoring disease progression, and ...
Nava Moghadasian, Niaki   +4 more
openaire   +3 more sources

AFP-MFL: accurate identification of antifungal peptides using multi-view feature learning

Briefings Bioinform., 2023
Recently, peptide-based drugs have gained unprecedented interest in discovering and developing antifungal drugs due to their high efficacy, broad-spectrum activity, low toxicity and few side effects.
Yitian Fang   +6 more
semanticscholar   +1 more source

Do combined assays of serum AFP, AFP-L3, DCP, GP73, and DKK-1 efficiently improve the clinical values of biomarkers in decision-making for hepatocellular carcinoma? A meta-analysis

Expert Review of Gastroenterology & Hepatology, 2021
Objectives: Serum biomarkers are valuable for clinical decision-making for patients with hepatocellular carcinoma (HCC), among which the most promising are AFP, AFP-L3, DCP, DKK-1, and GP73; however, the efficacy of using combined biomarkers remains ...
Yong Fang   +7 more
semanticscholar   +1 more source

Recent advances in optical biosensors for the detection of cancer biomarker α-fetoprotein (AFP)

Trends in Analytical Chemistry (TrAC), 2020
α-fetoprotein (AFP) as a target marker refers to albuminoid proteins, which is a tumor-related fetal protein, increasing the AFP concentration leads to various diseases, including liver cancer.
A. Kal-Koshvandi
semanticscholar   +1 more source

Preparing of Aptamer Responsive DNA Functionalized Hydrogels for the Sensitive Detection of AFP Using SERS Method.

Bioconjugate chemistry, 2020
Hepatocellular carcinoma (HCC), which is one of the three major cancers, has attracted growing attention due to its high mortality, health-care cost and circumscribed therapeutic methods.
Qi Wang   +5 more
semanticscholar   +1 more source

Machine Learning Based Predictive Model for AFP-Based Unidirectional Composite Laminates

IEEE Transactions on Industrial Informatics, 2020
Manufacturing of composites using automated fiber placement (AFP) is a complex process that involves large number of processing conditions and variables.
Chathura Wanigasekara   +5 more
semanticscholar   +1 more source

Maternal Serum AFP Screening

New England Journal of Medicine, 1978
Noninvasive diagnostic or creening technics have obvious appeal. When such approaches in pregnancy yield important information about fetal health, the vigor with which they will be pursued can easily be anticipated. This situation has been noted since the advent of maternal serum alpha-fetoprotein (AFP) testing, which made it possible to suspect a ...
A, Milunsky, E, Alpert
openaire   +2 more sources

Immunochemical Properties of Alpha-Fetoprotein (AFP) and Antibodies to Autologous AFP

Immunological Communications, 1978
Alpha-fetoprotein (AFP) is a strong immunogen when injected into another species, but does not elicit an immune response in the species of origin of the AFP. AFPs from different mammalian species are crossreactive. AFP and albumin show sequence homology. They do not crossreact in their native state, but their unfolded (reduced and carboxamidomethylated)
H, Jalanko, E, Engvall, E, Ruoslahti
openaire   +2 more sources

An fluorescent aptasensor for sensitive detection of tumor marker based on the FRET of a sandwich structured QDs-AFP-AuNPs.

Talanta: The International Journal of Pure and Applied Analytical Chemistry, 2019
The detection of alpha-fetoprotein (AFP) is of great importance for hepatocellular carcinoma (HCC) diagnosis, but it needs to be further improved because of poor sensitivity and complicated operating steps.
Lu Zhou   +7 more
semanticscholar   +1 more source

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