Results 51 to 60 of about 1,278,746 (295)

Spectroelectrochemical Dynamics of Dendritic Poly (Propylene imine)-Polythiophene Star Copolymer Aptameric 17β-Estradiol Biosensor

open access: yesInternational Journal of Electrochemical Science, 2011
Aptamers, which are in vitro-selected functional oligonucleotides, have been employed to design novel aptasensor due to their inherent high selectivity and affinity compared to traditional biorecognition elements.
Rasaq A. Olowu   +6 more
doaj   +1 more source

Attempts to identify Cassava Brown Streak Virus in western Democratic Republic of Congo [PDF]

open access: yes, 2020
Open Access ArticleRoot necrosis similar to those of the cassava brown streak disease (CBSD) were observed on cassava in western provinces of the Democratic Republic of Congo (DR.Congo) in the early 2000’s. However molecular laboratory diagnosis were not
Bakelana, Z.   +13 more
core   +1 more source

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

open access: yesAdvanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun   +14 more
wiley   +1 more source

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li   +22 more
wiley   +1 more source

Novel buffer for long-term preservation of DNA in biological material at room temperature

open access: yesBioTechniques
The collection and preservation of biological material before DNA analysis is critical for inter alia biomedical research, medical diagnostics, forensics and biodiversity conservation.
Mohaimin Kasu   +5 more
doaj   +1 more source

Seismicity along the Western Eurasia- Africa plate boundary [PDF]

open access: yes, 2009
extends from the Azores Islands to the Strait of Gibraltar. The interaction between Iberia and Africa results in a complex region located in the western part of the Eurasian-African plate boundary.
Bezzeghoud, M.
core  

EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets

open access: yesAdvanced Science, EarlyView.
Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang   +4 more
wiley   +1 more source

New and interesting Campylopus records from South Africa [PDF]

open access: yes, 2004
New records are presented based on a collection of Campylopus specimens made by the second author in the Western Cape Province of South Africa. The austral species Campylopus clavatus (R. Brown) Wils. in Hook. and Campylopus vesticaulis Mitt.
Frahm, Jan-Peter, Hedderson, Terry
core  

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

open access: yesAdvanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang   +10 more
wiley   +1 more source

Livestock Tango: U.S. and Latin America Dance Together, but Who Will Lead?

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT This study examines the competitiveness between Latin American and U.S. livestock and meat sectors. We employ a computable general equilibrium modeling framework to evaluate two scenarios: coordinated improvements in Latin American productivity, transport efficiency, and market access (Scenario I), and the minimum productivity gains required ...
Taís C. Menezes   +2 more
wiley   +1 more source

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