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Combatting African Animal Trypanosomiasis (AAT) in livestock: The potential role of trypanotolerance [PDF]

Veterinary Parasitology, 2016
African Animal Trypanosomiasis (AAT) is endemic in at least 37 of the 54 countries in Africa. It is estimated to cause direct and indirect losses to the livestock production industry in excess of US$ 4.5 billion per annum. A century of intervention has yielded limited success, owing largely to the extraordinary complexity of the host-parasite ...
Michael J Stear, Kylie Munyard, D M Groth   +2 more
exaly   +4 more sources

Bovine and small ruminant African animal trypanosomiasis in Nigeria – A review

Veterinary Parasitology: Regional Studies and Reports, 2018
Despite extensive attempts over many decades to control African Animal Trypanosomiasis (AAT) across the tsetse fly belt of Nigeria, AAT persists as major animal health problem causing severe morbidity and mortality in livestock. The large agricultural losses in turn have severe adverse impacts on sustainable agricultural development.
Isaiah Oluwafemi Ademola, Susan Welburn, Paul Olalekan Odeniran   +2 more
exaly   +5 more sources

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Animal African Trypanosomiasis in Nigeria: A long way from elimination/eradication

Acta Tropica, 2017
Animal African Trypanosomiasis (AAT) is a disease of livestock that directly hinders livestock production and therefore impedes the socio-economic development of sub-Saharan Africa. The establishment of the Pan-African Tsetse and Trypanosomiasis Eradication Campaign (PATTEC) was to enhance the goal of elimination and eradication of tsetse flies and AAT
John Asekhaen Ohiolei, Anthonius A. Eze, Clement Isaac   +2 more
exaly   +3 more sources

Animal African Trypanosomiasis: Time to Increase Focus on Clinically Relevant Parasite and Host Species [PDF]

Trends in Parasitology, 2016
Animal African trypanosomiasis (AAT), caused by Trypanosoma congolense and Trypanosoma vivax, remains one of the most important livestock diseases in sub-Saharan Africa, particularly affecting cattle. Despite this, our detailed knowledge largely stems from the human pathogen Trypanosoma brucei and mouse experimental models.
Jayne C. Hope, Liam J Morrison, Tim Rowan   +2 more
exaly   +3 more sources

Overview of the Vectors and Their Role in Transmission of African Animal Trypanosomiasis

2021
African animal trypanosomiasis (AAT) is a major constraint to livestock productivity, particularly in cattle and in camels. This chapter covers some general aspects of the arthropod vectors of animal trypanosomiasis, the tsetse flies Glossina spp., and to a lesser extent the biting flies.
Florence Njeri Wamwiri, Joanna Eseri Auma   +1 more
openaire   +1 more source

Animal models of human African trypanosomiasis--very useful or too far removed?

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2007
Animal models of human African trypanosomiasis, also known as sleeping sickness, have been used for many years both to investigate disease pathogenesis and to test novel drug therapies. Model systems used have included mice, rats and non-human primates such as monkeys.

exaly   +3 more sources

Immunology and Pathogenesis of African Animal Trypanosomiasis

1979
Publisher Summary This chapter discusses the immunology and pathogenesis of African animal trypanosomiasis. Hemoparasite infections represent some of the most important uncontrolled diseases of humans and animals in the tropics and other parts of the world.
J B, Henson, J C, Noel
openaire   +2 more sources

Human and animal African trypanosomiasis.

2015
Abstract This chapter describes the evolution of a One Health approach - the Stamp Out Sleeping Sickness (SOS) campaign - that has been key to the sustainable control of Trypanosoma brucei rhodesiense in humans and animals in Uganda.
S. C. Welburn, P. Coleman
openaire   +1 more source

Factors associated with persistence of African animal trypanosomiasis in Lango subregion, northern Uganda

Tropical Animal Health and Production, 2019
African animal trypanosomiasis (AAT) continues to inflict heavy losses on livestock production especially cattle in terms of decreased production and productivity in Uganda. AAT is a disease complex caused by tsetse fly-transmitted Trypanosoma brucei brucei, Trypanosoma brucei rhodesiense, Trypanosoma congolense, and Trypanosoma vivax.
James Bugeza, Susan Welburn
exaly   +3 more sources

Role of Kenya Tsetse and Trypanosomiasis Eradication Council (KENTTEC) in Control of African Animal Trypanosomiasis (AAT)/Nagana

2021
The role of the Kenya Tsetse and Trypanosomiasis Eradication Council (KENTTEC) in the control of animal trypanosomiasis is premised on the fact that a large proportion of animal trypanosomiasis in Kenya is tsetse transmitted. Tsetse distribution in Kenya is characterized by eight discontinuous belts defined by topographical, environmental and land-use.
Daniel O. Gamba, Pamela Akinyi Olet, Monicah W. Maichomo, Sylvia Muthama Korir, Isaiah Ndaburu Kiteto   +4 more
openaire   +1 more source