Results 1 to 10 of about 897 (118)

Chemotherapy of Human African Trypanosomiasis [PDF]

Interdisciplinary Perspectives on Infectious Diseases, 2009
Human Africa trypanosomiasis is a centuries-old disease which has disrupted sub-Saharan Africa in both physical suffering and economic loss. This article presents an update of classic chemotherapeutic agents, in use for >50 years and the recent ...
Cyrus J. Bacchi
doaj   +3 more sources

Human African trypanosomiasis

Lancet, The, 2010
Human African trypanosomiasis (sleeping sickness) occurs in sub-Saharan Africa. It is caused by the protozoan parasite Trypanosoma brucei, transmitted by tsetse flies. Almost all cases are due to Trypanosoma brucei gambiense, which is indigenous to west and central Africa.
Johannes Blum, François Chappuis, Christian Burri   +2 more
exaly   +8 more sources

Human African trypanosomiasis

Lancet, The, 2017
Human African trypanosomiasis (sleeping sickness) is a parasitic infection that almost invariably progresses to death unless treated. Human African trypanosomiasis caused devastating epidemics during the 20th century. Thanks to sustained and coordinated efforts over the past 15 years, the number of reported cases has fallen to an historically low level.
Philippe Büscher, Giuliano Cecchi, Vincent Jamonneau   +2 more
exaly   +5 more sources

The burden of human African trypanosomiasis.

PLoS Neglected Tropical Diseases, 2008
Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis.
Eric M Fèvre, Beatrix V Wissmann, Susan C Welburn, Pascal Lutumba   +3 more
doaj   +5 more sources

Epidemiology of human African trypanosomiasis

Clinical Epidemiology, 2014
Jose R Franco,1 Pere P Simarro,1 Abdoulaye Diarra,2 Jean G Jannin1 1World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health Organization, Inter Country Support ...
Franco JR, Simarro PP, Diarra A, Jannin JG   +3 more
doaj   +5 more sources

The detection and treatment of human African trypanosomiasis

Research and Reports in Tropical Medicine, 2012
Bernard Bouteille,1 Alain Buguet21Laboratory of Parasitology, Dupuytren University Hospital of Limoges, France; 2Polyclinic Marie-Louise Poto-Djembo, Pointe-Noire, CongoAbstract: Human African trypanosomiasis (HAT) is caused by the injection of ...
Bouteille B, Buguet A
doaj   +4 more sources

Towards the Atlas of human African trypanosomiasis [PDF]

International Journal of Health Geographics, 2009
Background Updated, accurate and comprehensive information on the distribution of human African trypanosomiasis (HAT), also known as sleeping sickness, is critically important to plan and monitor control activities.
Mattioli Raffaele C, Ruiz José A, Diarra Abdoulaye, Fèvre Eric M, Franco José R, Paone Massimo, Cecchi Giuliano, Simarro Pere P   +7 more
doaj   +4 more sources

Human African Trypanosomiasis

Infectious Disease Clinics of North America, 2019
Emmanuel Bottieau, Jan Clerinx
exaly   +3 more sources

Pathogenicity and virulence of African trypanosomes: From laboratory models to clinically relevant hosts

Virulence, 2023
African trypanosomes are vector-borne protozoa, which cause significant human and animal disease across sub-Saharan Africa, and animal disease across Asia and South America.
Liam J. Morrison, Pieter C. Steketee, Mabel D. Tettey, Keith R. Matthews   +3 more
doaj   +1 more source

Plant Terpenoids as Hit Compounds against Trypanosomiasis

Pharmaceuticals, 2022
Human African trypanosomiasis (sleeping sickness) and American trypanosomiasis (Chagas disease) are vector-borne neglected tropical diseases, caused by the protozoan parasites Trypanosoma brucei and Trypanosoma cruzi, respectively.
Raquel Durão, Cátia Ramalhete, Ana Margarida Madureira, Eduarda Mendes, Noélia Duarte   +4 more
doaj   +1 more source