Results 21 to 30 of about 11,156 (164)

Systematic Review and Meta-Analysis on Knowledge Attitude and Practices on African Animal Trypanocide Resistance

Tropical Medicine and Infectious Disease, 2022
Background: African trypanocide resistance is an emerging public health emergency whose control requires a revisit on farmer’s knowledge, attitudes, and practices in developing countries.
Keneth Iceland Kasozi, Ewan Thomas MacLeod, Charles Waiswa, Michael Mahero, Ibrahim Ntulume, Susan Christina Welburn   +5 more
doaj   +1 more source

Human African Trypanosomiasis Transmission, Kinshasa, Democratic Republic of Congo

Emerging Infectious Diseases, 2006
To investigate the epidemiology of human African trypanosomiasis (sleeping sickness) in Kinshasa, Democratic Republic of Congo, 2 entomologic surveys were conducted in 2005.
Gustave Simo, Philemon Mansinsa Diabakana, Victor Kande Betu Ku Mesu, Emile Zola Manzambi, Gaelle Ollivier, Tazoacha Asonganyi, Gerard Cuny, Pascal Grébaut   +7 more
doaj   +1 more source

Human African trypanosomiasis

BMJ, 2002
The re-emergence of sleeping sickness presents a major public health problem Human African trypanosomiasis or sleeping sickness is one of the most important but equally most neglected tropical infections. It is caused by a protozoan, Trypanosoma brucei ,which is transmitted to humans through the bite of a tsetse fly ( Glossina spp).1 Patchy ...
August, Stich, Paulo M, Abel, Sanjeev, Krishna   +2 more
openaire   +3 more sources

APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis

eLife, 2017
Reduced susceptibility to infectious disease can increase the frequency of otherwise deleterious alleles. In populations of African ancestry, two apolipoprotein-L1 (APOL1) variants with a recessive kidney disease risk, named G1 and G2, occur at high ...
Anneli Cooper, Hamidou Ilboudo, V Pius Alibu, Sophie Ravel, John Enyaru, William Weir, Harry Noyes, Paul Capewell, Mamadou Camara, Jacqueline Milet, Vincent Jamonneau, Oumou Camara, Enock Matovu, Bruno Bucheton, Annette MacLeod   +14 more
doaj   +1 more source

Hypocretin and Human African Trypanosomiasis [PDF]

Sleep, 2008
To detail clinical and polysomnographic characteristics in patients affected with Trypanosoma brucei gambiense (Tb.g.) human African trypanosomiasis (HAT) at different stages of evolution and to measure and compare cerebrospinal fluid (CSF) levels of hypocretin-1 with narcoleptic patients and neurologic controls.Twenty-five untreated patients affected ...
Yves, Dauvilliers, Sylvie, Bisser, Florian, Chapotot, Gedeao, Vatunga, Raymond, Cespuglio, Téofilo, Josenando, Alain, Buguet   +6 more
openaire   +2 more sources

The history of African trypanosomiasis

Parasites & Vectors, 2008
The prehistory of African trypanosomiasis indicates that the disease may have been an important selective factor in the evolution of hominids. Ancient history and medieval history reveal that African trypanosomiasis affected the lives of people living in
Steverding Dietmar
doaj   +1 more source

Molecular epidemiological studies on animal trypanosomiases in Ghana

Parasites & Vectors, 2012
Background African trypanosomes are extracellular protozoan parasites that are transmitted between mammalian hosts by the bite of an infected tsetse fly. Human African Trypanosomiasis (HAT) or sleeping sickness is caused by Trypanosoma brucei rhodesiense
Nakayima Jesca, Nakao Ryo, Alhassan Andy, Mahama Charles, Afakye Kofi, Sugimoto Chihiro   +5 more
doaj   +1 more source

Sleeping Sickness at the Crossroads

Tropical Medicine and Infectious Disease, 2020
Human African trypanosomiasis (HAT; sleeping sickness) is a disease with truly historic dimensions [...]
Christian Burri
doaj   +1 more source

Therapeutic Strategies against Leishmania and Trypanosoma

Pathogens, 2023
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (also known as Chagas disease, with Trypanosoma cruzi as the etiological
André L. S. Santos, Igor A. Rodrigues, Claudia M. d’Avila-Levy, Cátia L. Sodré, Koert Ritmeijer, Marta H. Branquinha   +5 more
doaj   +1 more source

Transforming the chemotherapy of human African trypanosomiasis. [PDF]

Clin Microbiol Rev
SUMMARY Prior to 2019, when the orally available drug fexinidazole began its clinical use, the treatment of human African trypanosomiasis (HAT) was complex and unsatisfactory for many reasons. Two sub-species of the Trypanosoma brucei parasite are responsible for HAT, namely the rhodesiense form found in ...
Barrett MP.
europepmc   +3 more sources