Results 11 to 20 of about 11,156 (164)

Control of Human African Trypanosomiasis in the Nola-Bilolo Focus, Central African Republic, 2020–2024: Outcome of Capacity Building, Improved Diagnosis and Treatment [PDF]

Journal of Parasitology Research
This study is aimed at evaluating the inclusion of miniature anion-exchange centrifugation technique (mAECT) in the diagnosis and fexinidazole as treatment of gHAT in Central African Republic (CAR) after capacity building.
Pierre-Marie Douzima, Mireille Cornelia Ingrid Denissio Morissi Nalingbo, Yvon Andjingbopou, Veerle Lejon, Romaric Nzoumbou-Boko   +4 more
doaj   +2 more sources

The burden of human African trypanosomiasis.

PLoS Neglected Tropical Diseases, 2008
Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis.
Eric M Fèvre, Beatrix V Wissmann, Susan C Welburn, Pascal Lutumba   +3 more
doaj   +5 more sources

Chemotherapy of Human African Trypanosomiasis [PDF]

Interdisciplinary Perspectives on Infectious Diseases, 2009
Human Africa trypanosomiasis is a centuries-old disease which has disrupted sub-Saharan Africa in both physical suffering and economic loss. This article presents an update of classic chemotherapeutic agents, in use for >50 years and the recent ...
Cyrus J. Bacchi
doaj   +3 more sources

Reemergence of Human African Trypanosomiasis Caused by Trypanosoma brucei rhodesiense, Ethiopia [PDF]

Emerging Infectious Diseases
We report 4 cases of human African trypanosomiasis that occurred in Ethiopia in 2022, thirty years after the last previously reported case in the country. Two of 4 patients died before medicine became available.
Adugna Abera, Tihitina Mamecha, Ebise Abose, Belachew Bokicho, Agune Ashole, Tesfahun Bishaw, Abinet Mariyo, Buzayehu Bogale, Haileyesus Terefe, Henok Tadesse, Mahlet Belachew, Hailemariam Difabachew, Araya Eukubay, Solomon Kinde, Abraham Ali, Feyesa Regasa, Fikre Seife, Zeyede Kebede, Mesfin Wossen, Getachew Tollera, Mesay Hailu, Nigus Manaye, Nick Van Reet, Gerardo Priotto, Johan van Griensven, Myrthe Pareyn, Geremew Tasew   +26 more
doaj   +2 more sources

Current Treatments to Control African Trypanosomiasis and One Health Perspective

Microorganisms, 2022
Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same etiological agent, Trypanosoma brucei.
Alberto Venturelli, Lorenzo Tagliazucchi, Clara Lima, Federica Venuti, Giulia Malpezzi, George E. Magoulas, Nuno Santarem, Theodora Calogeropoulou, Anabela Cordeiro-da-Silva, Maria Paola Costi   +9 more
doaj   +3 more sources

Towards the Atlas of human African trypanosomiasis [PDF]

International Journal of Health Geographics, 2009
Background Updated, accurate and comprehensive information on the distribution of human African trypanosomiasis (HAT), also known as sleeping sickness, is critically important to plan and monitor control activities.
Mattioli Raffaele C, Ruiz José A, Diarra Abdoulaye, Fèvre Eric M, Franco José R, Paone Massimo, Cecchi Giuliano, Simarro Pere P   +7 more
doaj   +4 more sources

Human African trypanosomiasis

The Lancet, 2010
Human African trypanosomiasis (sleeping sickness) occurs in sub-Saharan Africa. It is caused by the protozoan parasite Trypanosoma brucei, transmitted by tsetse flies. Almost all cases are due to Trypanosoma brucei gambiense, which is indigenous to west and central Africa.
Brun, R., Blum, J., Chappuis, F., Burri, C.   +3 more
  +10 more sources

Pathogenicity and virulence of African trypanosomes: From laboratory models to clinically relevant hosts

Virulence, 2023
African trypanosomes are vector-borne protozoa, which cause significant human and animal disease across sub-Saharan Africa, and animal disease across Asia and South America.
Liam J. Morrison, Pieter C. Steketee, Mabel D. Tettey, Keith R. Matthews   +3 more
doaj   +1 more source

Plant Terpenoids as Hit Compounds against Trypanosomiasis

Pharmaceuticals, 2022
Human African trypanosomiasis (sleeping sickness) and American trypanosomiasis (Chagas disease) are vector-borne neglected tropical diseases, caused by the protozoan parasites Trypanosoma brucei and Trypanosoma cruzi, respectively.
Raquel Durão, Cátia Ramalhete, Ana Margarida Madureira, Eduarda Mendes, Noélia Duarte   +4 more
doaj   +1 more source

Unusual neurological presentation of second stage African trypanosomiasis in a young boy: a case report

BMC Pediatrics, 2022
Background In South Sudan, sleeping sickness is a frequent condition caused by human African trypanosomiasis. There are two stages that are well-known.
Etedal Ahmed A. Ibrahim, Mohammed Gasm Elseed M. Elmahal, Khabab Abbasher Hussien Mohamed Ahmed, Elfatih A. Hasabo, Mohammed Eltahier Abdalla Omer   +4 more
doaj   +1 more source