Human African trypanosomiasis [PDF]
BMJ, 2009 Human African trypanosomiasis (sleeping sickness) occurs in sub-Saharan Africa. It is caused by the protozoan parasite Trypanosoma brucei, transmitted by tsetse flies.
Abel +143 more
core +9 more sources
Trypanosoma brucei brucei invasion and T-cell infiltration of the brain parenchyma in experimental sleeping sickness: timing and correlation with functional changes [PDF]
, 2016 Background: The timing of Trypanosoma brucei entry into the brain parenchyma to initiate the second, meningoencephalitic stage of human African trypanosomiasis or sleeping sickness is currently debated and even parasite invasion of the neuropil has ...
Bentivoglio, Marina +8 more
core +76 more sources
Control of Human African Trypanosomiasis in the Nola-Bilolo Focus, Central African Republic, 2020–2024: Outcome of Capacity Building, Improved Diagnosis and Treatment [PDF]
Journal of Parasitology ResearchThis study is aimed at evaluating the inclusion of miniature anion-exchange centrifugation technique (mAECT) in the diagnosis and fexinidazole as treatment of gHAT in Central African Republic (CAR) after capacity building.
Pierre-Marie Douzima +4 more
doaj +2 more sources
Case of Nigeria-Acquired Human African Trypanosomiasis in United Kingdom, 2016 [PDF]
Emerging Infectious Diseases, 2017 Human African trypanosomiasis has not been reported in Nigeria since 2012. Nevertheless, limitations of current surveillance programs mean that undetected infections may persist.
Akish Luintel +6 more
doaj +5 more sources
The Lancet, 2017 Human African trypanosomiasis (sleeping sickness) is a parasitic infection that almost invariably progresses to death unless treated. Human African trypanosomiasis caused devastating epidemics during the 20th century. Thanks to sustained and coordinated efforts over the past 15 years, the number of reported cases has fallen to an historically low level.
Buscher, P. +3 more
exaly +6 more sources
Chemotherapy of Human African Trypanosomiasis [PDF]
Interdisciplinary Perspectives on Infectious Diseases, 2009 Human Africa trypanosomiasis is a centuries-old disease which has disrupted sub-Saharan Africa in both physical suffering and economic loss. This article presents an update of classic chemotherapeutic agents, in use for >50 years and the recent ...
Cyrus J. Bacchi
doaj +3 more sources
Reemergence of Human African Trypanosomiasis Caused by Trypanosoma brucei rhodesiense, Ethiopia [PDF]
Emerging Infectious DiseasesWe report 4 cases of human African trypanosomiasis that occurred in Ethiopia in 2022, thirty years after the last previously reported case in the country. Two of 4 patients died before medicine became available.
Adugna Abera +26 more
doaj +2 more sources
Epidemiology of human African trypanosomiasis
Clinical Epidemiology, 2014 Jose R Franco,1 Pere P Simarro,1 Abdoulaye Diarra,2 Jean G Jannin1 1World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health Organization, Inter Country Support ...
Franco JR +3 more
doaj +5 more sources
The burden of human African trypanosomiasis.
PLoS Neglected Tropical Diseases, 2008 Human African trypanosomiasis (HAT, or sleeping sickness) is a protozoan parasitic infection caused by Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense. These are neglected tropical diseases, and T.b. rhodesiense HAT is a zoonosis.
Eric M Fèvre +3 more
doaj +5 more sources
Focus: Human African trypanosomiasis [PDF]
Nature Reviews Microbiology, 2004 D. Kioy, J. Jannin, N. Mattock
openaire +3 more sources