Results 31 to 40 of about 13,726 (210)

Therapeutic Strategies against Leishmania and Trypanosoma

Pathogens, 2023
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (also known as Chagas disease, with Trypanosoma cruzi as the etiological
André L. S. Santos, Igor A. Rodrigues, Claudia M. d’Avila-Levy, Cátia L. Sodré, Koert Ritmeijer, Marta H. Branquinha   +5 more
doaj   +1 more source

Improvements on Restricted Insecticide Application Protocol for Control of Human and Animal African Trypanosomiasis in Eastern Uganda [PDF]

, 2014
African trypanosomes constrain livestock and human health in Sub-Saharan Africa, and aggravate poverty and hunger of these otherwise largely livestock-keeping communities. To solve this, there is need to develop and use effective and cheap tsetse control
Jan Hatendorf (651760), John David Kabasa (651762), Kabasa, John David, Charles Waiswa (236117), John David Kabasa, Charles Waiswa, Hatendorf Jan, Thrusfield Michael, Muhanguzi Dennis, Susan Christina Welburn, Welburn Susan Christina, Picozzi, Kim, Waiswa, Charles, Susan Christina Welburn (573233), Jan Hatendorf, Dennis Muhanguzi, Michael Thrusfield (651761), Kabasa John David, Hattendorf, Jan, Thrusfield, Michael, Welburn, Susan Christina, Waiswa Charles, Muhanguzi, Dennis, Michael Thrusfield, Kim Picozzi (77649), Dennis Muhanguzi (651759), Hatendorf, Jan, Kim Picozzi, Picozzi Kim   +28 more
core   +1 more source

Human African trypanosomiasis caused by Trypanosoma brucei gambiense: The first case report in China

International Journal of Infectious Diseases, 2019
We report the first imported case in China of human African trypanosomiasis (HAT), caused by Trypanosoma brucei gambiense, in a sailor returning from Gabon in 2014.
Nian Chen, Ke Jin, Jingjing Xu, Jianfu Zhang, Yali Weng   +4 more
doaj   +1 more source

Tsetse distribution, trypanosome infection rates, and small-holder livestock producers’ capacity enhancement for sustainable tsetse and trypanosomiasis control in Busia, Kenya

Tropical Medicine and Health, 2020
Background Tsetse flies are the cyclical vectors of both human and animal diseases. Kenya’s commitment to eradicate tsetse and trypanosomiasis dates to the 1980s through various control approaches which were spearheaded by the African Union.
Ferdinard Adungo, Tom Mokaya, Olipher Makwaga, Matilu Mwau   +3 more
doaj   +1 more source

Chemotherapy of second stage human African trypanosomiasis : comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet monkeys [PDF]

, 2015
Human African trypanosomiasis (HAT, sleeping sickness) ranks among the most neglected tropical diseases based on limited availability of drugs that are safe and efficacious, particularly against the second stage (central nervous system [CNS]) of ...
Wang, Michael Z., Shelley Ching, Bridges, Arlene S., Bridges, Arlene S, Wang, Michael Z, Gem, Charles O, Michael Z Wang, Wolf, Kristina K, Wang, Michael Zhuo, Wolf, Kristina K., Ching, Shelley, Mutuku, James N., Arlene S Bridges, Boykin, David W, Murilla, Grace A, Murilla, Grace A., Qiang Liu, Paine, Mary F., Boykin, David W., Grace A Murilla, Jones, Susan K, Charles O Gem, James N Mutuku, Mary F Paine, Susan K Jones, Richard R Tidwell, Mutuku, James N, Paine, Mary F, David W Boykin, Liu, Qiang, Tidwell, Richard R., John K Thuita, Gem, Charles O., Kristina K Wolf, Jones, Susan K., Brun, Reto, Thuita, John K., Boykin, David, Reto Brun, Piane, Mary F., Tidwell, Richard R, Thuita, John K   +41 more
core   +1 more source

Human African trypanosomiasis

, 2013
Human African trypanosomiasis or sleeping sickness is a neglected tropical disease that affects populations in sub-Saharan Africa. The disease is caused by infection with the gambiense and rhodesiense subspecies of the extracellular parasite Trypanosoma brucei, and is transmitted to humans by bites of infected tsetse flies.
Lejon, Veerle, Bentivoglio, M., Franco, J.R.   +2 more
openaire   +3 more sources

Pharmacological investigations on current and new drugs for treatment of human African trypanosomiasis [PDF]

, 1999
Trypanosomiasis remains a major threat to humans in sub-Saharan Africa with 55-60 million people in 36 countries at risk of infection with T.b. gambiense or T.b. rhodesiense.
Keiser, Jennifer
core   +1 more source

A molecular mechanism for eflornithine resistance in African trypanosomes [PDF]

, 2010
Human African trypanosomiasis, endemic to sub-Saharan Africa, is invariably fatal if untreated. Its causative agent is the protozoan parasite Trypanosoma brucei.
Creek Darren, Watson David G., Burchmore, Richard J S, Barrett, M.P., Michael P. Barrett, Woods, DJ, Pui Ee Wong, Vincent, I.M., Darren Creek, Vincent, IM, Kamleh, M.A., Richard J S Burchmore, Wong, P.E., Kamleh, Mohammed A, Woods, Debra J, Creek, Darren, Richard J. S. Burchmore, Wong, PE, Vincent, Isabel M, Isabel M Vincent, Michael P Barrett, Isabel M. Vincent, Kamleh, MA, Watson, DG, Woods, D.J., Wong, Pui Ee, Woods Debra J., Mohammed A. Kamleh, David G. Watson, Barrett, Michael P, Creek, D., Barrett Michael P., Barrett, MP, Burchmore, R.J.S., Wong Pui Ee, David G Watson, Kamleh Mohammed A., Vincent Isabel M., Watson, David G, Burchmore, RJS, Creek, D, Watson, D.G., Debra J Woods, Debra J. Woods, Mohammed A Kamleh, Burchmore Richard J. S.   +45 more
core   +1 more source

Accuracy of five algorithms to diagnose gambiense human African trypanosomiasis.

, 2011
Algorithms to diagnose gambiense human African trypanosomiasis (HAT, sleeping sickness) are often complex due to the unsatisfactory sensitivity and/or specificity of available tests, and typically include a screening (serological), confirmation ...
Francesco Checchi, Gerardo Priotto, Daniel Chandramohan, Checchi Francesco, Unni Karunakara, Priotto Gerardo, Checchi, F, Priotto, Gerardo, Priotto, G, Checchi, Francesco, Chappuis, F, Chandramohan, D, Chandramohan, Daniel, Karunakara Unni, François Chappuis, Karunakara, U, Karunakara, Unni, Chappuis, François, Chappuis François, Chandramohan Daniel   +19 more
core   +1 more source

Biological and pharmacological investigations of novel diamidines in animal models of human African trypanosomiasis [PDF]

, 2013
"African sleeping sickness, also called human African trypanosomiasis (HAT), results from the infection of humans with either of two protozoan parasites, Trypanosoma brucei gambiense and T. b. rhodesiense. HAT is transmitted by tsetse flies (Glossina spp)
Kibuthu, John Thuita
core   +1 more source