Results 51 to 60 of about 11,156 (164)
Smallholder dairy farmers in Tanzania face livestock disease challenges that drive imprudent antimicrobial use and fuel antimicrobial resistance (AMR). In Bagamoyo, poor husbandry and limited disease control result in high prevalence of vector‐borne infections, commonly treated with oxytetracycline (OTC).
Ridhiwan I. Ramadhani +1 more
wiley +1 more source
This study aimed to identify trypanosomes infecting cattle in Malawi in order to understand the importance of cattle in the transmission dynamics of Human African Trypanosomiasis (HAT) and Animal African Trypanosomosis (AAT).
Marsela Megasari +8 more
doaj +1 more source
Impact of pulmonary African trypanosomes on the immunology and function of the lung
A number of human African trypanosomiasis, or sleeping sickness, patients suffer from respiratory symptoms commonly attributed to cardiac insufficiency. Here, the authors characterise the role of pulmonary Trypanosoma brucei in respiratory infection.
Dorien Mabille +14 more
doaj +1 more source
An integrated computational‐experimental workflow enabled CRK12‐guided hit discovery against Trypanosoma brucei under limited structural and ligand data. The workflow of virtual screening and anti‐T. brucei bioassays identified 4 hit compounds, including three low‐micromolar leads (IC50 = 1.47, 0.81, and 1.33 μM). ABSTRACT Human African trypanosomiasis
Qin Li +11 more
wiley +1 more source
Clinical management of East African trypanosomiasis in South Africa: Lessons learned
Background: East African trypanosomiasis is an uncommon, potentially lethal disease if not diagnosed and treated in a timely manner. South Africa, as a centre for emergency medical evacuations from much of sub-Saharan Africa, receives a high proportion ...
John Frean +4 more
doaj +1 more source
Rewilding is often summarized with the three C's of Carnivores, Cores and Corridors. In this essay we propose a complementary perspective that focuses on the three B's of Bovines, Buffers and Barriers. This complementary perspective draws attention to rewilding as a social (rather than only ecological) challenge and is illustrated with insights from ...
Wisse Van Engelen +7 more
wiley +1 more source
Human African trypanosomiasis in travellers to Kenya [PDF]
In this issue, two cases are described of human African trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense. They occurred recently in European tourists returning from Masai Mara area, Kenya, to Germany and Belgium, respectively [1,2]. These are, to our knowledge, the first two HAT cases described in travellers to Kenya in the last 12 years ...
Gobbi F, Bisoffi Z
openaire +4 more sources
Accelerating towards human African trypanosomiasis elimination: Issues and opportunities
Human African trypanosomiasis (HAT) has been an alarming global public health issue. The disease affects mainly poor and marginalized people in low-resource settings and is caused by two subspecies of haemoflagellate parasite, Trypanosoma brucei and ...
Kingsley Uchenna Ozioko +6 more
doaj +1 more source
Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia +4 more
wiley +1 more source
Milk and milk products are important sources of nutrients to human and animals, but due to its physicochemical characteristics and nutritional value, it serves as an excellent medium for growth of microorganisms. Most of smallholder dairy farmers have no training on livestock husbandry and milk handling practices.
Fortunate Shija, Hezron Emmanuel Nonga
wiley +1 more source

