Results 71 to 80 of about 6,740 (162)

Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman, Janine Aucamp, Helena D. Janse van Rensburg, Christina Kannigadu, Rotondwa Mphephu, Andrew J. Swarts, Keisuke Suganuma, David D. N'Da   +7 more
wiley   +1 more source

Mathematical Model for Describing the Transmission of Animal African Trypanosomiasis in Cattle

Asian Research Journal of Mathematics
In this paper, we have formulated a mathematical model for the transmission dynamics of African Animal Trypanosomiasis (AAT) by incorporating spraying of the tsetse y population(vector) and treating the cattle population (host) as control strategies.
Conrad Akello, David Ambogo, Richard Opiyo   +2 more
openaire   +1 more source

Geographical Variation in the Gut Microbiota of Duttaphrynus melanostictus: Relative Contributions of Environmental Filtering and Host Physiological Modulation

Ecology and Evolution, Volume 16, Issue 7, July 2026.
We examined gut microbial communities in 385 Asian common toads (Duttaphrynus melanostictus) from 14 populations across southern China, using 16S rRNA sequencing to assess the roles of climate, topography, and host traits in shaping community structure.
Di K. Zhu, Nan Wen, Ke Y. Peng, Lin L. Jiang, Jin Li, Li Zhao   +5 more
wiley   +1 more source

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia, Valentina D'Onghia, Valentina Semeraro, Esposito Susanna, Maria Elisabeth Street   +4 more
wiley   +1 more source

The study of trypanosome species circulating in domestic animals in two human African trypanosomiasis foci of Côte d'Ivoire identifies pigs and cattle as potential reservoirs of Trypanosoma brucei gambiense.

PLoS Neglected Tropical Diseases, 2017
BackgroundImportant control efforts have led to a significant reduction of the prevalence of human African trypanosomiasis (HAT) in Côte d'Ivoire, but the disease is still present in several foci.
Martial Kassi N'Djetchi, Hamidou Ilboudo, Mathurin Koffi, Jacques Kaboré, Justin Windingoudi Kaboré, Dramane Kaba, Fabrice Courtin, Bamoro Coulibaly, Pierre Fauret, Lingué Kouakou, Sophie Ravel, Stijn Deborggraeve, Philippe Solano, Thierry De Meeûs, Bruno Bucheton, Vincent Jamonneau   +15 more
doaj   +1 more source

Cow Milk Risk Factors Associated With Bacterial Contaminations Along Dairy Value Chain in Lushoto and Handeni Districts, Tanzania

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Milk and milk products are important sources of nutrients to human and animals, but due to its physicochemical characteristics and nutritional value, it serves as an excellent medium for growth of microorganisms. Most of smallholder dairy farmers have no training on livestock husbandry and milk handling practices.
Fortunate Shija, Hezron Emmanuel Nonga
wiley   +1 more source

Identifying Cattle Breed-Specific Partner Choice of Transcription Factors during the African Trypanosomiasis Disease Progression Using Bioinformatics Analysis

Vaccines, 2020
African Animal Trypanosomiasis (AAT) is a disease caused by pathogenic trypanosomes which affects millions of livestock every year causing huge economic losses in agricultural production especially in sub-Saharan Africa.
Abirami Rajavel, Felix Heinrich, Armin Otto Schmitt, Mehmet Gültas   +3 more
doaj   +1 more source

Interventions for Neglected Diseases Caused by Kinetoplastid Parasites: A One Health Approach to Drug Discovery, Development, and Deployment

Pharmaceuticals
Kinetoplastids are protozoa that possess a unique organelle called a kinetoplast. These include the parasites Trypanosoma cruzi, T. brucei and related African trypanosomes, and Leishmania spp.
Godwin U. Ebiloma, Amani Alhejeli, Harry P. de Koning   +2 more
doaj   +1 more source

Resolving the apparent transmission paradox of African sleeping sickness.

PLoS Biology, 2019
Human African trypanosomiasis (HAT), or African sleeping sickness, is a fatal disease found throughout sub-Saharan Africa. The disease is close to elimination in many areas, although it was similarly close to elimination once before and subsequently ...
Paul Capewell, Katie Atkins, William Weir, Vincent Jamonneau, Mamadou Camara, Caroline Clucas, Nono-Raymond K Swar, Dieudonne M Ngoyi, Brice Rotureau, Paul Garside, Alison P Galvani, Bruno Bucheton, Annette MacLeod   +12 more
doaj   +1 more source

Serological tests for gambiense human African trypanosomiasis detect antibodies in cattle

Parasites & Vectors, 2017
Background Serological tests for gambiense human African trypanosomiasis (gHAT) detect antibodies to antigens on the cell surface of bloodstream trypanosomes.
Enock Matovu, Annah Kitibwa, Albert Picado, Sylvain Biéler, Paul R. Bessell, Joseph Mathu Ndung’u   +5 more
doaj   +1 more source