Independent evolution of pain insensitivity in African mole-rats: origins and mechanisms. [PDF]
AbstractThe naked mole-rat (Heterocephalus glaber) is famous for its longevity and unusual physiology. This eusocial species that lives in highly ordered and hierarchical colonies with a single breeding queen, also discovered secrets enabling somewhat pain-free living around 20 million years ago.
Smith ESJ, Park TJ, Lewin GR.
europepmc +14 more sources
Clocks Ticking in the Dark: A Review of Biological Rhythms in Subterranean African Mole-Rats [PDF]
Biological rhythms are rhythmic fluctuations of biological functions that occur in almost all organisms and on several time scales. These rhythms are generated endogenously and entail the coordination of physiological and behavioural processes to ...
Maria K. Oosthuizen +3 more
doaj +2 more sources
Otoacoustic emissions in African mole-rats [PDF]
African mole-rats display highly derived hearing that is characterized by low sensitivity and a narrow auditory range restricted to low frequencies < 10 kHz. Recently, it has been suggested that two species of these rodents do not exhibit distortion product otoacoustic emissions (DPOAE), which was interpreted as evidence for a lack of cochlear ...
Geoffrey A. Manley +6 more
openaire +6 more sources
Naked mole-rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles [PDF]
The naked mole-rat Heterocephalus glaber is a eusocial mammal exhibiting extreme longevity (37-year lifespan), extraordinary resistance to hypoxia and absence of cardiovascular disease.
Chris G. Faulkes +10 more
doaj +13 more sources
The Somatosensory World of the African Naked Mole-Rat
The naked mole-rat (Heterocephalus glaber) is famous for its longevity and unusual physiology. This eusocial species that lives in highly ordered and hierarchical colonies with a single breeding queen, also discovered secrets enabling somewhat pain-free living around 20 million years ago.
Lewin, G. +5 more
openaire +4 more sources
Phylogenetic modeling of enhancer shifts in African mole-rats reveals regulatory changes associated with tissue-specific traits. [PDF]
Changes in gene regulation are thought to underlie most phenotypic differences between species. For subterranean rodents such as the naked mole-rat, proposed phenotypic adaptations include hypoxia tolerance, metabolic changes, and cancer resistance ...
Parey E +8 more
europepmc +10 more sources
From Mice to Mole-Rats: Species-Specific Modulation of Adult Hippocampal Neurogenesis [PDF]
Rodent populations living in their natural environments have very diverse ecological and life history profiles that may differ substantially from that of conventional laboratory rodents.
Maria K. Oosthuizen
doaj +2 more sources
Functional, Morphological, and Evolutionary Characterization of Hearing in Subterranean, Eusocial African Mole-Rats. [PDF]
Naked mole-rats are highly vocal, eusocial, subterranean rodents with, counterintuitively, poor hearing. The causes underlying their altered hearing are unknown.
Pyott SJ +13 more
europepmc +2 more sources
Cannabinoid Modulation of Development and Neuroprotection in African Naked Mole-Rats [PDF]
Naked mole-rats display typical subterranean features, but also has unusual characteristics even among subterranean mammals due to unusually large colony sizes. The naked mole-rat provides insights into the complex interplay of evolutionary adaptations to the constraints of subterranean living, the hallmark of which is extreme hypoxia tolerance.
Brigitte M Browe (9908262)
openaire +2 more sources
Book Reviews: African Mole-Rats: Ecology and Eusociality
Book Title: African Mole-Rats: Ecology and Eusociality,Book Authors: Nigel C. Bennett&Chris G.Faulkes (eds).Cambridge University Press. 2000. Pp. 273. Price £35.00. ISBN 0 521 77199 4.
O’Riain, M.J.
openaire +2 more sources

