Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber). [PDF]
PLoS Biology, 2008 In all mammals, tissue inflammation leads to pain and behavioral sensitization to thermal and mechanical stimuli called hyperalgesia. We studied pain mechanisms in the African naked mole-rat, an unusual rodent species that lacks pain-related ...
Thomas J Park +12 more
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Morphological and molecular characterization of an undescribed vestibuliferid ciliate from the captive-bred naked mole-rat, [PDF]
International Journal for Parasitology: Parasites and WildlifeThe intestinal ciliates of the naked mole-rat ( Heterocephalus glaber ) remain poorly characterized. Previous reports identified a Balantidium or suggested an association with Meiostoma ; however, their taxonomic identities have not been verified using ...
Mami Takase, Toshihiro Tokiwa
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Spectroscopic Analysis of the Extracellular Matrix Hierarchical Structure in Naked Mole-Rat Skin [PDF]
GelsNaked mole-rats are extremely long-lived rodents with a lifespan of up to 40 years, during which cellular and tissue aging is rarely observed. In this study, we analyzed the extracellular matrix (ECM) of naked mole-rat skin at the molecular level to ...
Tetsuya Adachi +15 more
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BIO Web of Conferences, 2020 Naked mole rat is the long-lived and tumor-resistant rodent. Naked mole rat possesses multiple adaptations that may contribute to longevity and cancer-resistance.
Evdokimov Alexey +4 more
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Non-Invasive Quantification of Faecal and Urine Reproductive Hormone Metabolites in the Naked Mole-Rat (Heterocephalus glaber) [PDF]
Animals, 2023 The naked mole-rat (Heterocephalus glaber) occurs in colonies with a distinct dominance hierarchy, including one dominant, breeding female (the queen), 1–3 breeding males, and non-reproductive subordinates of both sexes that are reproductively suppressed
Tshepiso Lesedi Majelantle +5 more
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Epigenetic aging of the demographically non-aging naked mole-rat [PDF]
Nature Communications, 2022 The exceptionally long-lived naked mole-rat is characterized by the lack of increased mortality with aging. Here the authors perform epigenetic studies to show that naked mole-rats epigenetically age despite their non-increasing mortality rate.
Csaba Kerepesi +15 more
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PLoS ONE, 2011 The naked mole-rat (Heterocephalus glaber) is a long-lived, cancer resistant rodent and there is a great interest in identifying the adaptations responsible for these and other of its unique traits.
Chuanfei Yu +9 more
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Invariant γδTCR natural killer-like effector T cells in the naked mole-rat [PDF]
Nature CommunicationsThe naked mole-rat (Heterocephalus glaber) is a long-lived rodent species showing resistance to the development of cancer. Although naked mole-rats have been reported to lack natural killer (NK) cells, γδ T cell-based immunity has been suggested in this ...
Guillem Sanchez Sanchez +7 more
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Social structure predicts genital morphology in African mole-rats. [PDF]
PLoS ONE, 2009 BACKGROUND:African mole-rats (Bathyergidae, Rodentia) exhibit a wide range of social structures, from solitary to eusocial. We previously found a lack of sex differences in the external genitalia and morphology of the perineal muscles associated with the
Marianne L Seney +4 more
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Protracted neuronal maturation in a long-lived, highly social rodent.
PLoS ONE, 2022 Naked mole-rats are a long-lived rodent species (current lifespan >37 years) and an increasingly popular biomedical model. Naked mole-rats exhibit neuroplasticity across their long lifespan.
Mariela Faykoo-Martinez +12 more
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