Epigenetic aging of the demographically non-aging naked mole-rat [PDF]
Nature Communications, 2022 The exceptionally long-lived naked mole-rat is characterized by the lack of increased mortality with aging. Here the authors perform epigenetic studies to show that naked mole-rats epigenetically age despite their non-increasing mortality rate.
Csaba Kerepesi +15 more
doaj +3 more sources
Non-Invasive Quantification of Faecal and Urine Reproductive Hormone Metabolites in the Naked Mole-Rat (Heterocephalus glaber) [PDF]
Animals, 2023 The naked mole-rat (Heterocephalus glaber) occurs in colonies with a distinct dominance hierarchy, including one dominant, breeding female (the queen), 1–3 breeding males, and non-reproductive subordinates of both sexes that are reproductively suppressed
Tshepiso Lesedi Majelantle +5 more
doaj +2 more sources
Digital dissection of the masticatory muscles of the naked mole-rat, Heterocephalus glaber (Mammalia, Rodentia) [PDF]
PeerJ, 2014 The naked mole-rat, Heterocephalus glaber, of the family Bathyergidae is a subterranean rodent that feeds on underground roots and tubers and digs extensive tunnel systems with its incisors.
Philip G. Cox, Chris G. Faulkes
doaj +7 more sources
Acid and inflammatory sensitisation of naked mole-rat colonic afferent nerves [PDF]
Molecular Pain, 2020 Acid sensing in the gastrointestinal tract is required for gut homeostasis and the detection of tissue acidosis caused by ischaemia, inflammation and infection.
James RF Hockley +6 more
doaj +3 more sources
Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P [PDF]
Molecular Pain, 2010 Recent research has proposed a pathway in which sensory neurons expressing the capsaicin activated ion channel TRPV1 are required for histamine-induced itch and subsequent scratching behavior.
Lewin Gary R +3 more
doaj +4 more sources
Naked mole-rat macrophage polarization
Медицинская иммунологияThe naked mole-rat (NMR) is a unique long-lived rodent with low cancer incidence. Understanding the molecular mechanisms that NMR evolved to control aging and tumorigenesis is important for biomedicine.
E. A. Gorshkova +4 more
doaj +2 more sources
Invariant γδTCR natural killer-like effector T cells in the naked mole-rat [PDF]
Nature CommunicationsThe naked mole-rat (Heterocephalus glaber) is a long-lived rodent species showing resistance to the development of cancer. Although naked mole-rats have been reported to lack natural killer (NK) cells, γδ T cell-based immunity has been suggested in this ...
Guillem Sanchez Sanchez +7 more
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Naked mole-rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles [PDF]
Nature CommunicationsThe naked mole-rat Heterocephalus glaber is a eusocial mammal exhibiting extreme longevity (37-year lifespan), extraordinary resistance to hypoxia and absence of cardiovascular disease.
Chris G. Faulkes +10 more
doaj +2 more sources
Aggression, Boldness, and Exploration Personality Traits in the Subterranean Naked Mole-Rat (Heterocephalus glaber) Disperser Morphs [PDF]
Animals, 2022 Animal personality traits (consistent behavioral differences between individuals in their behavior across time and/or situation) affect individual fitness through facets, such as dispersal.
Tshepiso Lesedi Majelantle +4 more
doaj +2 more sources
End fire linear antenna array synthesis using differential evolution inspired Adaptive Naked Mole Rat Algorithm [PDF]
Scientific Reports, 2023 Linear antenna arrays (LAAs) play a critical role in smart system communication applications such as the Internet of Things (IoT), mobile communication and beamforming.
Harbinder Singh +4 more
doaj +2 more sources