Results 81 to 90 of about 72,115 (295)

Genetic Variations of African Swine Fever Virus: Major Challenges and Prospects

Viruses
African swine fever (ASF) is a contagious viral disease affecting pigs and wild boars. It typically presents as a hemorrhagic fever but can also manifest in various forms, ranging from acute to asymptomatic.
Shengmei Chen, Tao Wang, Rui Luo, Zhanhao Lu, Jing Lan, Yuan Sun, Qiang Fu, Huarong Qiu   +7 more
semanticscholar   +1 more source

Full genome sequence for the African swine fever virus outbreak in the Dominican Republic in 1980

Scientific Reports, 2023
African swine fever is a lethal disease of domestic pigs, geographically expanding as a pandemic, that is affecting countries across Eurasia and severely damaging their swine production industry.
Edward Spinard, V. O'Donnell, E. Vuono, A. Rai, Charronne F. Davis, E. Ramírez-Medina, N. Espinoza, Alyssa Valladares, M. Borca, D. Gladue   +9 more
semanticscholar   +1 more source

Establishment of Interspecies Somatic Cell Nuclear Transfer and Transgene‐Free Inducible Pluripotent Stem Cells for Versatile Conservation of the Germplasm Resource of Wild Boar

Animal Research and One Health, EarlyView.
Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao, Xinyi Zhou, Shigang Gu, Jianbo Li, Jing Wang, Yurong Zhang, Wenxuan Zhao, Xinhua Wei, Liting Lu, Quanmin Zhao, Yongye Huang, Dawei Yu   +11 more
wiley   +1 more source

SY18ΔL60L: a new recombinant live attenuated African swine fever virus with protection against homologous challenge

Frontiers in Microbiology, 2023
IntroductionAfrican swine fever (ASF) is an acute and highly contagious disease and its pathogen, the African swine fever virus (ASFV), threatens the global pig industry.
Jinjin Yang, Jinjin Yang, Jinjin Yang, Rongnian Zhu, Rongnian Zhu, Yanyan Zhang, Yanyan Zhang, Jiaqi Fan, Xintao Zhou, Huixian Yue, Huixian Yue, Qixuan Li, Faming Miao, Faming Miao, Teng Chen, Teng Chen, Lijuan Mi, Lijuan Mi, Fei Zhang, Fei Zhang, Shoufeng Zhang, Shoufeng Zhang, Aidong Qian, Rongliang Hu, Rongliang Hu   +24 more
doaj   +1 more source

African swine fever at the wildlife-livestock interface: challenges for management and outbreak response within invasive wild pigs in the United States

Frontiers in Veterinary Science
African swine fever (ASF) causes significant morbidity and mortality in both domestic and wild suids (Sus scrofa), and disease outbreaks convey profound economic costs to impacted industries due to death loss, the cost of culling exposed/infected animals
Vienna R. Brown, Ryan S. Miller, Kim M. Pepin, Keith M. Carlisle, Merril A. Cook, Cole F. Vanicek, Lindsey Holmstrom, Lisa T. Rochette, T. Smyser   +8 more
semanticscholar   +1 more source

The African swine fever virus I10L protein inhibits the NF-κB signaling pathway by targeting IKKβ

Journal of Virology, 2023
Proinflammatory factors play important roles in the pathogenesis of African swine fever virus (ASFV), which is the causative agent of African swine fever (ASF), a highly contagious and severe hemorrhagic disease.
Xing Chen, Lianfeng Li, Zhongning Yang, Meilin Li, Shuai Fan, Lan-Fang Shi, Zixin Ren, Xuezhi Cao, Yuhang Zhang, Shi-chong Han, Bo Wan, H. Qiu, Gai-Ping Zhang, Wen-Rui He   +13 more
semanticscholar   +1 more source

Advances in Double‐Stranded DNA Targeting Technologies

Exploration, EarlyView.
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen, Yiqun Liu, Yingjie Hao, Yifan Bo, Xiaochuan Dai, Shihui Wang, Tian Xia, Xin Su, Huiyu Liu   +8 more
wiley   +1 more source

Theaflavin inhibits African swine fever virus replication by disrupting lipid metabolism through activation of the AMPK signaling pathway in virto

Virus Research, 2023
African swine fever virus (ASFV) is the etiological agent of African swine fever (ASF), which is one of the most harmful swine diseases in the pig industry because of its nearly 100% mortality rate in domestic pigs and results in incalculable economic ...
Yang Chen, Zhi Wei, Zebu Song, Hao Chang, Yanchen Guo, Yankuo Sun, Heng Wang, Zezhong Zheng, Guihong Zhang   +8 more
doaj   +1 more source

African swine fever virus NAM P1/95 is a mixture of genotype I and genotype VIII viruses

Microbiology Resource Announcements
African swine fever virus causes a lethal hemorrhagic disease of domestic pigs. The NAM P1/1995 isolate was originally described as B646L genotype XVIII; however, full genome sequencing revealed that this assignment was incorrect.
L. Goatley, Graham L. Freimanis, Chandana Tennakoon, A. Bastos, L. Heath, C. Netherton   +5 more
semanticscholar   +1 more source

African Swine Fever Virus: A Review

Life, 2022
African swine fever (ASF) is a viral disease with a high fatality rate in both domestic pigs and wild boars. ASF has greatly challenged pig-raising countries and also negatively impacted regional and national trade of pork products.
Zhaoyao Li, Wenxian Chen, Zilong Qiu, Yuwan Li, Jindai Fan, Keke Wu, Xiaowen Li, Mingqiu Zhao, Hongxing Ding, Shuangqi Fan, Jinding Chen   +10 more
semanticscholar   +1 more source