Results 71 to 80 of about 1,646,700 (223)

African Swine Fever [PDF]

, 2023
At the time of writing this chapter, a global pandemic of African swine fever (ASF) is ongoing with the virus having moved from Eastern Europe, Asia, and into the Caribbean—leaving swine production in devastation along the way.
Brown, Vienna R., Lenoch, Julianna B., Bowden, Courtney F.   +2 more
core  

A phage-displayed nanobody-based competitive immunoassay for the detection of African swine fever virus antibodies

Virology Journal
African swine fever (ASF) is a highly infectious and devastating disease that poses a significant threat to the global swine industry. The rapid spread of ASF and its ongoing pandemics continue to impact pig farming worldwide. The absence of an effective
Wenting Chen, Jifei Yang, Qingli Niu, Jinming Wang, Yanghe Liu, Xuesai Li, Yaru Zhao, Zhonghui Zhang, Zhijie Liu, Guiquan Guan, Hong Yin   +10 more
doaj   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Evaluation of the Immunogenicity of a Pool of Recombinant Lactococcus lactis Expressing Eight Antigens of African Swine Fever Virus in a Mouse Model

Veterinary Sciences
African swine fever (ASF), caused by African swine fever virus (ASFV), poses a great threat to the global pig industry. There is an urgent demand for effective and safe vaccines to address this threat.
Jingshan Huang, Tianqi Gao, Zhanhao Lu, Dailang Zhong, Mingzhi Li, Hua-Ji Qiu, Yongfeng Li, Hongxia Wu, Yuan Sun   +8 more
doaj   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Factors associated with the introduction of classical swine fever virus into pig herds in the central area of the 1997/98 epidemic in the Netherlands [PDF]

, 2001
A matched case-control study of 135 infected and 99 uninfected pig herds from the central area of the 1997 to 1998 epidemic of classical swine fever (CSF) in The Netherlands was undertaken to identify factors associated with the introduction of the virus.
Stegeman, J.A., Jong, M.C.M., de, Elbers, A.R.W.   +2 more
core   +1 more source

A broadly applicable split-luciferase biosensor approach for rapid antibody detection in emerging infectious diseases

Applied Microbiology and Biotechnology
Conventional immunoassays such as ELISA are widely used in serological testing, yet their reliance on multi-step workflows and labeled reagents limits diagnostic scalability and speed.
Xuesai Li, Qingli Niu, Jinming Wang, Yijun Chai, Xiaoyu Zou, Hualin Sun, Hong Yin, Siyuan Dou, Guiquan Guan, Jifei Yang   +9 more
doaj   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Studies on the epidemiology of classical swine fever in the republic of Korea [PDF]

, 2012
Classical swine fever (CSF) is a serious and highly infectious viral disease of domestic pigs and wild boar, which is caused by a single stranded RNA pestivirus.
Che, Sunoh
core  

An attenuated African swine fever virus expressing the E2 glycoprotein of classical swine fever virus protects pigs against challenge of both viruses

Emerging Microbes and Infections
African swine fever (ASF) and classical swine fever (CSF) are highly contagious diseases with high morbidity and mortality rates resulting in an enormous impact on the global pig industry.
Jiwen Zhang, Fang Li, Weiye Chen, Yongfeng Li, Zhenjiang Zhang, Ronghong Hua, Renqiang Liu, Yuanmao Zhu, Encheng Sun, Huaji Qiu, Zhigao Bu, Dongming Zhao   +11 more
doaj   +1 more source