Results 71 to 80 of about 1,740,141 (209)

Development of a Ready‐To‐Use Bioluminescence Immunosensor for the One‐Step Sensitive Detection of Antibodies Against African Swine Fever Virus

Microbial Biotechnology
Rapid and reliable analytical techniques play important roles in various research fields and are particularly crucial for diagnosing infectious diseases in clinical settings.
Zhonghui Zhang, Xuesai Li, Qingli Niu, Jinming Wang, Yanghe Liu, Dossêh Jean Apôtre Afayibo, Wenting Chen, Songlin Yang, Hong Yin, Guiquan Guan, Jifei Yang   +10 more
doaj   +1 more source

Evidence of West Nile Virus Infections in Wild Boars (Sus scrofa) in the Netherlands, 2018–2021

Zoonoses and Public Health, Volume 73, Issue 7, Page 670-679, November 2026.
ABSTRACT Introduction Orthoflaviviruses are emerging in Europe and have potential significant impact on animal and public health. Usutu virus (USUV) and West Nile virus (WNV) have been first detected in the Netherlands in 2016 and 2020, respectively. Wild boars (Sus scrofa) have been suggested as an interesting population to detect the circulation of ...
Kiki Streng, Eduardo de Freitas Costa, Sophie van Oort, Renate Hakze‐van der Honing, Gebbiena Bron, Carl Andreas Grøntvedt, Wim H. M. van der Poel, Nathanaël Hozé, Michel Counotte   +8 more
wiley   +1 more source

Newcastle Disease Virus-Vectored African Swine Fever Virus Antigen Cocktail Delays the Onset of ASFV-SY18 but Is Not Protective

Microorganisms
African Swine Fever (ASF) is a highly contagious viral disease threatening the global pig industry. Currently, only two gene-deleted live attenuated vaccines are approved, exclusively in Vietnam, and their long-term effectiveness and safety are unproven,
Qian Li, Yiqian Jiang, Min Zheng, Xuefei Sun, Lili Hui, Yanyan Zhang, Huixian Yue, Yu Qi, Siqi Li, Junnan Ke, Qixuan Li, Boli Ma, Xiaoying Jia, Fengjie Wang, Lijuan Mi, Shoufeng Zhang, Faming Miao, Shuchao Wang, Fei Zhang, Teng Chen, Rongliang Hu   +20 more
doaj   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, Volume 13, Issue 57, 14 October 2026.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Molecular Characterization of African Swine Fever Virus, China, 2018

, 2018
On August 3, 2018, an outbreak of African swine fever in pigs was reported in China. We subjected a virus from an African swine fever–positive pig sample to phylogenetic analysis.
Yongqiang Zhang, Zhiliang Wang, Jinming Li, Lin Li, Shengqiang Ge, Fuxiao Liu, Hua Wang, Jingyue Bao, Xiaoxu Fan, Tiangang Xu, Weijie Ren, Xiaodong Wu, Qinghua Wang, Chunju Liu, Yutian Liu   +14 more
core   +1 more source

Autophagy promotes p72 degradation and capsid disassembly during the early phase of African swine fever virus infection

Journal of Virology
During viral infections, autophagy functions as a cell-intrinsic defense mechanism by facilitating the delivery of virions or viral components to the endosomal/lysosomal pathway for degradation.
Jie Song, Jiangnan Li, Shuai Li, Gaihong Zhao, Tingting Li, Xin Chen, Boli Hu, Jia Liu, Xinyu Lai, Sitong Liu, Qiongqiong Zhou, Li Huang, Changjiang Weng   +12 more
doaj   +1 more source

African Swine Fever [PDF]

, 2023
At the time of writing this chapter, a global pandemic of African swine fever (ASF) is ongoing with the virus having moved from Eastern Europe, Asia, and into the Caribbean—leaving swine production in devastation along the way.
Brown, Vienna R., Lenoch, Julianna B., Bowden, Courtney F.   +2 more
core  

Pseudorabies virus DNA polymerase processivity factor pUL42 inhibits type I IFN production by negatively regulating cGAS-STING signaling pathway

Journal of Virology
Pseudorabies (PR), caused by the PR virus (PRV), is an acute infectious disease in livestock and various wild animals. PRV has developed several immune evasion mechanisms to antagonize the host’s antiviral immune response.
Guangqiang Ye, Jiaxiu Gao, Haoxuan Cao, Xiaohong Liu, Hongyang Liu, Shanghui Wang, Yunfei Liu, Longfei Han, Qiongqiong Zhou, Yandong Tang, Jin Tian, Liping Huang, Li Huang, Zhaoxia Zhang, Changjiang Weng   +14 more
doaj   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, Volume 6, Issue 5, October 2026.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Construction of Recombinant PRV Expressing PRRSV Antigens and Evaluation of Their Protective Efficacy in Pigs Against Homologous Challenge

Vaccines
Background/Objectives: Porcine reproductive and respiratory syndrome virus (PRRSV) remains a major threat to the global swine industry, while the emergence of variant pseudorabies virus (PRV) strains has further complicated disease control in China. This
Shanghui Wang, Yunfei Liu, Longfei Han, Liguo Gao, Guangqiang Ye, Xiang Zhao, Yi Liu, Hongyang Liu, Zhaoxia Zhang, Changjiang Weng   +9 more
doaj   +1 more source