Results 1 to 10 of about 6,867 (199)

A Re-Evaluation of African Swine Fever Genotypes Based on p72 Sequences Reveals the Existence of Only Six Distinct p72 Groups

Viruses, 2023
The African swine fever virus (ASFV) is currently causing a world-wide pandemic of a highly lethal disease in domestic swine and wild boar. Currently, recombinant ASF live-attenuated vaccines based on a genotype II virus strain are commercially available
Edward J Spinard, Anthony V Signore, Manuel V Borca   +2 more
exaly   +6 more sources

Identification of Linear Epitopes in the C-Terminal Region of ASFV p72 Protein

Microorganisms, 2023
African swine fever, which is induced by the African swine fever virus (ASFV), poses a significant threat to the global pig industry due to its high lethality in domestic pigs and wild boars.
Ning Kong, Hao Zheng, Hai Yu
exaly   +4 more sources

A Mutant of Africa Swine Fever Virus Protein p72 Enhances Antibody Production and Regulates the Production of Cytokines

Viruses
African swine fever virus (ASFV) is a severe threat to the global pig industry, and domestic pigs mostly develop severe clinical manifestations upon viral invasion. Currently, there is no available vaccine against ASFV.
Mingzhi Li, Lingbao Kong, Yanni Zhang
exaly   +4 more sources

Structural Design and Assessing of Recombinantly Expressed African Swine Fever Virus p72 Trimer in Saccharomyces cerevisiae

Frontiers in Microbiology, 2022
In an effort to control the outbreak of the African Swine Fever Virus (ASFV), there is an urgent need to develop an effective method to prevent the pandemic, including vaccines and diagnostic methods.
Kaiwen Meng, Yueping Zhang, Geng Meng
exaly   +3 more sources

Identification of Novel Linear Epitopes in P72 Protein of African Swine Fever Virus Recognized by Monoclonal Antibodies

Frontiers in Microbiology, 2022
African swine fever (ASF) is one of the highly contagious and lethal diseases among domestic pigs and wild boars. The capsid protein P72 of African swine fever virus (ASFV) is very important for the diagnosis and vaccine development. However, the epitope
Aijian Qin, Hongjun Chen, Jianqiang Ye
exaly   +3 more sources

Identification of p72 Epitopes of African Swine Fever Virus and Preliminary Application

Frontiers in Microbiology, 2023
African swine fever virus (ASFV) causes a highly lethal hemorrhagic viral disease (ASF) of pigs that results in serious losses in China and elsewhere. The development of a vaccine and diagnosis technology for ASFV is essential to prevent and control the ...
Sicheng Yang, Yunyun Ma, Guangqing Zhou
exaly   +3 more sources

Identification and Characterization of Nanobodies Specifically Against African Swine Fever Virus Major Capsid Protein p72

Frontiers in Microbiology, 2022
African swine fever virus (ASFV) is a large and very complex DNA virus. The major capsid protein p72 is the most predominant structural protein and constitutes the outmost icosahedral capsid of the virion.
Hong Yin, Jifei Yang, Zhijie Liu
exaly   +3 more sources

African Swine Fever Virus P72 Genotyping Tool.

Microbiology Resource Announcements
Historically, genotyping of African swine fever virus was based on partial sequencing of B646L (p72). Until recently, the number of differences that defined genotypes was ambiguous. This tool allows a sequence to be uploaded and will report its closest matches along with its likely p72 genotype.
Edward J Spinard, Manuel V Borca, Douglas P. Gladue   +2 more
exaly   +3 more sources

Evaluation of Cellular Immunity with ASFV Infection by Swine Leukocyte Antigen (SLA)—Peptide Tetramers

Viruses, 2021
African swine fever virus (ASFV) causes acute hemorrhagic fever in domestic pigs and wild boars, resulting in incalculable economic losses to the pig industry. As the mechanism of viral infection is not clear, protective antigens have not been discovered
Wenqiang Sun, He Zhang, Wenhui Fan, Lihong He, Teng Chen, Xintao Zhou, Yu Qi, Lei Sun, Rongliang Hu, Tingrong Luo, Wenjun Liu, Jing Li   +11 more
doaj   +1 more source

Indirect ELISA Using Multi–Antigenic Dominants of p30, p54 and p72 Recombinant Proteins to Detect Antibodies against African Swine Fever Virus in Pigs

Viruses, 2022
African swine fever (ASF) caused by ASF virus (ASFV) is a fatal disease in pigs and results in great economic losses. Due to the lack of available vaccines and treatments, serological diagnosis of ASF plays a key role in the surveillance program, but due
Dexin Li, Qin Zhang, Yutian Liu, Miaoli Wang, Lei Zhang, Liyuan Han, Xuefei Chu, Guofei Ding, Yingchao Li, Yanmeng Hou, Sidang Liu, Zhiliang Wang, Yihong Xiao   +12 more
doaj   +1 more source