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African Swine Fever Virus (ASFV): Immunity and Vaccine Development [PDF]

open access: yesVaccines, 2023
African swine fever virus (ASFV) is the causative agent of the highly contagious disease African swine fever (ASF), which can result in mortality rates of up to 100% in pigs infected by virulent strains [...]
Kiramage Chathuranga, Jong-Soo Lee
doaj   +4 more sources

Genotyping of African Swine Fever Virus (ASFV) Isolates in Romania with the First Report of Genotype II in Symptomatic Pigs [PDF]

open access: yesVeterinary Sciences, 2021
The World Organisation for Animal Health has listed African swine fever as the most important deadly disease in domestic swine around the world. The virus was recently brought from South-East Africa to Georgia in 2007, and it has since expanded to Russia,
Andrei Ungur   +8 more
doaj   +2 more sources

Seroprevalence of African Swine Fever Virus and Farm Management Practices in Nepal: A Cross-Sectional Study. [PDF]

open access: yesVet Med Sci
A cross‐sectional study on seroprevalence of African swine fever virus was conducted across pig farms in Bagmati Province. Of the 324 samples screened, seven tested positive, with an overall seroprevalence of 2.16% . ABSTRACT Background African swine fever (ASF) is a contagious fatal viral disease of pigs caused by ASF virus (ASFV).
Prajapati M   +5 more
europepmc   +2 more sources

Establishment and Evaluation of a Multicolor Latex Microsphere-Based Lateral Flow Immunoassay for the Simultaneous Detection of Antibodies Against African and Classical Swine Fever Viruses. [PDF]

open access: yesTransbound Emerg Dis
African swine fever (ASF), a highly fatal disease often termed the “number one killer” of pigs, presents clinical symptoms indistinguishable from classical swine fever (CSF), such as fever, diarrhea, and vomiting, complicating on‐site differential diagnosis.
Chen J   +13 more
europepmc   +2 more sources

A Method for the Analysis of African Swine Fever by Viral Metagenomic Sequencing

open access: yesFrontiers in Veterinary Science, 2021
In 2018, there was an outbreak of African swine fever (ASF) in China, which spread to other provinces in the following 3 years and severely damaged China's pig industry. ASF is caused by the African swine fever virus (ASFV).
ChiHai Ji   +58 more
doaj   +1 more source

Characterization of a Novel African Swine Fever Virus p72 Genotype II from Nigeria

open access: yesViruses, 2023
African swine fever (ASF) is a high-consequence transboundary hemorrhagic fever of swine. It continues to spread across the globe causing socio-economic issues and threatening food security and biodiversity. In 2020, Nigeria reported a major ASF outbreak,
Aruna Ambagala   +19 more
doaj   +1 more source

African Swine Fever Virus F317L Protein Inhibits NF-κB Activation To Evade Host Immune Response and Promote Viral Replication

open access: yesmSphere, 2021
African swine fever (ASF) is one of the most important pig diseases, causing a high case fatality rate and trade restrictions upon reported outbreaks. The limited understanding of the functions of the proteins of the causative agent, African swine fever ...
Jinping Yang   +10 more
doaj   +1 more source

Evaluation of an I177L gene-based five-gene-deleted African swine fever virus as a live attenuated vaccine in pigs

open access: yesEmerging Microbes and Infections, 2023
African swine fever (ASF) is a highly contagious disease of domestic and wild pigs caused by the African swine fever virus (ASFV). The current research on ASF vaccines focuses on the development of naturally attenuated, isolated, or genetically ...
Yingnan Liu   +17 more
doaj   +1 more source

Deletion of the EP296R Gene from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs

open access: yesViruses, 2022
African swine fever virus (ASFV) causes a lethal disease (ASF) in domestic pigs, African swine fever (ASF). ASF is currently producing a pandemic affecting pig production across Eurasia, leading to a shortage of food accessibility.
Elizabeth A. Vuono   +10 more
doaj   +1 more source

The 24.5-kb Left Variable Region Is Not a Determinant for African Swine Fever Virus to Replicate in Primary Porcine Alveolar Macrophages

open access: yesViruses, 2022
African swine fever (ASF) is a widespread hemorrhagic and highly contagious infectious disease caused by African swine fever virus (ASFV), currently threatening the pig industry worldwide. Here, we demonstrated that the cell-adapted strain ASFV-P121 with
Rui Luo   +6 more
doaj   +1 more source

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