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African Swine Fever Virus (ASFV): Immunity and Vaccine Development [PDF]

open access: yesVaccines, 2023
African swine fever virus (ASFV) is the causative agent of the highly contagious disease African swine fever (ASF), which can result in mortality rates of up to 100% in pigs infected by virulent strains [...]
Kiramage Chathuranga, Jong-Soo Lee
doaj   +6 more sources

Genotyping of African Swine Fever Virus (ASFV) Isolates in Romania With the First Report of Genotype II in Symptomatic Pigs [PDF]

open access: yesVeterinary Sciences, 2021
The World Organisation for Animal Health has listed African swine fever as the most important deadly disease in domestic swine around the world. The virus was recently brought from South-East Africa to Georgia in 2007, and it has since expanded to Russia,
Andrei Daniel Mihalca   +2 more
exaly   +4 more sources

Regulation of Antiviral Immune Response by African Swine Fever Virus (ASFV) [PDF]

open access: yesVirologica Sinica, 2022
African swine fever (ASF) is a highly contagious and acute hemorrhagic viral disease with a high mortality approaching 100% in domestic pigs. ASF is an endemic in countries in sub-Saharan Africa. Now, it has been spreading to many countries, especially in Asia and Europe.
Wen-Hai Feng, Xiaojie Zheng
exaly   +4 more sources

African Swine Fever Virus (ASFV): Biology, Genomics and Genotypes Circulating in Sub-Saharan Africa [PDF]

open access: yesViruses, 2021
African swine fever (ASF) is a highly infectious and fatal haemorrhagic disease of pigs that is caused by a complex DNA virus of the genus Asfivirus and Asfarviridae African suids family. The disease is among the most devastating pig diseases worldwide including Africa.
Gabriel Shirima   +2 more
exaly   +8 more sources

Transcriptome Profiling in Swine Macrophages Infected With African Swine Fever Virus (ASFV) Uncovers the Complex and Close Relationship With Host [PDF]

open access: yesPathogens, 2022
African swine fever virus (ASFV) is a pathogen to cause devastating and economically significant diseases in domestic and feral swine. ASFV mainly infects macrophages and monocytes and regulates its replication process by affecting the content of cytokines in the infected cells.
Hongxing Ding, Yuwan Li, Zhaoyao Li
exaly   +5 more sources

A Method for the Analysis of African Swine Fever by Viral Metagenomic Sequencing

open access: yesFrontiers in Veterinary Science, 2021
In 2018, there was an outbreak of African swine fever (ASF) in China, which spread to other provinces in the following 3 years and severely damaged China's pig industry. ASF is caused by the African swine fever virus (ASFV).
ChiHai Ji   +58 more
doaj   +1 more source

Characterization of a Novel African Swine Fever Virus p72 Genotype II from Nigeria

open access: yesViruses, 2023
African swine fever (ASF) is a high-consequence transboundary hemorrhagic fever of swine. It continues to spread across the globe causing socio-economic issues and threatening food security and biodiversity. In 2020, Nigeria reported a major ASF outbreak,
Aruna Ambagala   +19 more
doaj   +1 more source

African Swine Fever Virus F317L Protein Inhibits NF-κB Activation To Evade Host Immune Response and Promote Viral Replication

open access: yesmSphere, 2021
African swine fever (ASF) is one of the most important pig diseases, causing a high case fatality rate and trade restrictions upon reported outbreaks. The limited understanding of the functions of the proteins of the causative agent, African swine fever ...
Jinping Yang   +10 more
doaj   +1 more source

Evaluation of an I177L gene-based five-gene-deleted African swine fever virus as a live attenuated vaccine in pigs

open access: yesEmerging Microbes and Infections, 2023
African swine fever (ASF) is a highly contagious disease of domestic and wild pigs caused by the African swine fever virus (ASFV). The current research on ASF vaccines focuses on the development of naturally attenuated, isolated, or genetically ...
Yingnan Liu   +17 more
doaj   +1 more source

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