Results 11 to 20 of about 2,737,561 (202)

Evaluation in Swine of a Recombinant Georgia 2010 African Swine Fever Virus Lacking the I8L Gene

Viruses, 2020
African swine fever virus (ASFV) is the causative agent of African swine fever, a disease currently causing significant economic losses in Europe and Asia. Specifically, the highly virulent ASFV strain Georgia 2010 (ASFV-G) is producing disease outbreaks
Elizabeth Vuono, Elizabeth Ramirez-Medina, Sarah Pruitt, Ayushi Rai, Ediane Silva, Nallely Espinoza, James Zhu, Lauro Velazquez-Salinas, Douglas P. Gladue, Manuel V. Borca   +9 more
doaj   +2 more sources

African Swine Fever Virus Multigene Family Genes Inhibit the Type-I Interferon Response by Acting on the NFκB and IRF3 Signalling Pathways at the Transcription Factor Level or below

Proceedings, 2020
African Swine Fever Virus (ASFV) is a haemorrhagic infection of swine, which routinelydisplays 100% lethality. [...]
Samuel Connell, Ana Reis, Anusyah Rathakrishnan, Sarah Gilbert, Linda Dixon   +4 more
doaj   +3 more sources

Modulation of Host Antiviral Innate Immunity by African Swine Fever Virus: A Review

Animals, 2022
African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious and fatal disease found in swine. However, the viral proteins and mechanisms responsible for immune evasion are poorly understood, which has severely hindered ...
Wen-Rui He, Jin Yuan, Yu-He Ma, Cheng-Yan Zhao, Zhong-Yuan Yang, Yuhang Zhang, Shichong Han, Bo Wan, Gai-Ping Zhang   +8 more
doaj   +2 more sources

Evaluation in Swine of a Recombinant African Swine Fever Virus Lacking the MGF-360-1L Gene

Viruses, 2020
The African swine fever (ASF) pandemic is currently affecting pigs throughout Eurasia, resulting in significant swine production losses. The causative agent, ASF virus (ASFV), is a large, structurally complex virus with a genome encoding more than 160 ...
Elizabeth Ramirez-Medina, Elizabeth A. Vuono, Ayushi Rai, Sarah Pruitt, Ediane Silva, Lauro Velazquez-Salinas, James Zhu, Douglas P. Gladue, Manuel V. Borca   +8 more
doaj   +2 more sources

Replication Characteristics of African Swine Fever Virus (ASFV) Genotype I E70 and ASFV Genotype II Belgium 2018/1 in Perivenous Macrophages Using Established Vein Explant Model. [PDF]

Viruses
African Swine Fever Virus (ASFV), resulting in strain-dependent vascular pathology, leading to hemorrhagic fever, is an important pathogen in swine. The pathogenesis of ASFV is determined by the array and spatial distribution of susceptible cells within ...
Han S, Oh D, Balmelle N, Cay AB, Ren X, Droesbeke B, Tignon M, Nauwynck H.   +7 more
europepmc   +2 more sources

The African Swine Fever Virus (ASFV) Topoisomerase II as a Target for Viral Prevention and Control. [PDF]

Vaccines (Basel), 2020
African swine fever (ASF) is, once more, spreading throughout the world. After its recent reintroduction in Georgia, it quickly reached many neighboring countries in Eastern Europe. It was also detected in Asia, infecting China, the world’s biggest pig producer, and spreading to many of the surrounding countries.
Coelho J, Leitão A.
europepmc   +5 more sources

Deletion of African Swine Fever Virus (ASFV) H240R Gene Attenuates the Virulence of ASFV by Enhancing NLRP3-Mediated Inflammatory Responses. [PDF]

J Virol, 2023
African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious and acute hemorrhagic viral disease of domestic pigs, with a high mortality approaching 100%. ASFV has spread rapidly worldwide and caused huge economic losses and ecological consequences.
Huang L, Liu H, Ye G, Liu X, Chen W, Wang Z, Zhao D, Zhang Z, Feng C, Hu L, Yu H, Zhou S, Zhang X, He X, Zheng J, Bu Z, Li J, Weng C.   +17 more
europepmc   +3 more sources

Environmental DNA (eDNA) contamination patterns of African swine fever virus (ASFV) in swine transport vehicles in the Philippines. [PDF]

Vet Med (Praha)
Since its introduction in 2019, African swine fever (ASF) has spread to all regions of the Philippines, affecting 73 out of its 82 provinces. To assess the environmental DNA (eDNA) contamination patterns of the ASF virus (ASFV) in swine transport vehicles and evaluate its measures of association, a total of 450 environmental swabs from 30 ...
Bartolome MJ, Aguirre LAM, Poliquit CM, Besas I, Angeles JG, Rabajante J, Camba S, Del Valle F, Ambrocio A, Caguicla F, Bustamante MG, Umali D.   +11 more
europepmc   +4 more sources

The Influence of the Temperature on Effectiveness of Selected Disinfectants Against African Swine Fever Virus (ASFV). [PDF]

Viruses
African swine fever (ASF) is one of the most economically significant diseases of pigs caused by African swine fever virus (ASFV). Due to the lack of effective and safe vaccines, one of the crucial measures to protect farms from the introduction of the ASFV is to apply a strict regime of biosecurity and disinfection.
Juszkiewicz M, Walczak M, Woźniakowski G, Pejsak Z, Podgórska K.   +4 more
europepmc   +4 more sources

I329L: A Dual Action Viral Antagonist of TLR Activation Encoded by the African Swine Fever Virus (ASFV). [PDF]

Viruses, 2023
The African Swine Fever Virus (ASFV) is an economically important, large DNA virus which causes a highly contagious and frequently fatal disease in domestic pigs. Due to the acute nature of the infection and the complexity of the protective porcine anti-ASFV response, there is no accepted vaccine in use. As resistance to ASFV is known to correlate with
Correia S, Moura PL, Ventura S, Leitão A, Parkhouse RME.   +4 more
europepmc   +5 more sources