Results 11 to 20 of about 45,459 (317)

African swine fever virus – variants on the rise

Emerging Microbes & Infections, 2022
African swine fever virus (ASFV), a large and complex DNA-virus circulating between soft ticks and indigenous suids in sub-Saharan Africa, has made its way into swine populations from Europe to Asia.
J. Forth, S. Calvelage, M. Fischer, J. Hellert, Julia Sehl-Ewert, H. Roszyk, P. Deutschmann, Adam Reichold, M. Lange, H. Thulke, C. Sauter-Louis, D. Höper, S. Mandyhra, M. Sapachova, M. Beer, S. Blome   +15 more
semanticscholar   +5 more sources

Development of a Ready-To-Use Bioluminescence Immunosensor for the One-Step Sensitive Detection of Antibodies Against African Swine Fever Virus. [PDF]

Microb Biotechnol
A ready‐to‐use bioluminescence immunosensor for rapid, one‐step detection of ASFV antibodies, offering high specificity, high sensitivity, and ease of use, with promising applications for point‐of‐care diagnostics. ABSTRACT Rapid and reliable analytical techniques play important roles in various research fields and are particularly crucial for ...
Zhang Z, Li X, Niu Q, Wang J, Liu Y, Afayibo DJA, Chen W, Yang S, Yin H, Guan G, Yang J.   +10 more
europepmc   +2 more sources

African swine fever virus I73R is a critical virulence-related gene: A potential target for attenuation

Proceedings of the National Academy of Sciences of the United States of America, 2023
Significance African swine fever virus (ASFV) is the etiological agent for the highly contagious and fatal African swine fever (ASF) in pigs. The virulence-related genes and the mechanism of immune escape of ASFV are unclear, raising safety concerns of ...
Yingnan Liu, Zhou Shen, Zhenhua Xie, Yingying Song, Yao Li, R. Liang, L. Gong, Dong-dong Di, Jianqi Liu, Jingyi Liu, Zongyan Chen, Wanqi Yu, Lu Lv, Qi Zhong, Xinxin Liao, Chuanwen Tian, Rongrong Wang, Qingqing Song, Heng Wang, Guiqing Peng, Hongjun Chen   +20 more
semanticscholar   +1 more source

African swine fever virus attachment protein [PDF]

Journal of Virology, 1991
Treatment of African swine fever virus particles with nonionic detergents released proteins p35, p17, p14, and p12 from the virion. Of these proteins, only p12 bound to virus-sensitive Vero cells but not to virus-resistant L or IBRS2 cells. The binding of p12 was abolished by whole African swine fever virus and not by similar concentrations of subviral
Ángel L. Carrascosa, Isabel Sastre, Eladio Viñuela   +2 more
openalex   +4 more sources

Deletion of African Swine Fever Virus (ASFV) H240R Gene Attenuates the Virulence of ASFV by Enhancing NLRP3-Mediated Inflammatory Responses

Journal of Virology, 2023
African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious and acute hemorrhagic viral disease of domestic pigs, with a high mortality approaching 100%.
Li Huang, Hongyang Liu, Guangqiang Ye, Xiaohong Liu, Wei-ye Chen, Zilong Wang, Dongmin Zhao, Zhaoxia Zhang, Chun-ling Feng, Liang Hu, Huibin Yu, Shijun Zhou, Xianfeng Zhang, Xijun He, Jun Zheng, Z. Bu, Jiangnan Li, C. Weng   +17 more
semanticscholar   +1 more source

A new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine

Emerging Microbes and Infections, 2023
African swine fever (ASF) is an acute and highly contagious lethal infectious disease in swine that severely threatens the global pig industry. At present, a safe and efficacious vaccine is urgently required to prevent and control the disease.
Wenming Liu, Hengchun Li, Bo Liu, T. Lv, Chenchen Yang, Si Chen, Liqiang Feng, L. Lai, Ziyuan Duan, Xinwen Chen, Pingchao Li, Suhua Guan, Ling Chen   +12 more
semanticscholar   +1 more source

African Swine Fever Virus: A Review [PDF]

Viruses, 2017
African swine fever (ASF) is a highly contagious viral disease of swine which causes high mortality, approaching 100%, in domestic pigs. ASF is caused by a large, double stranded DNA virus, ASF virus (ASFV), which replicates predominantly in the cytoplasm of macrophages and is the only member of the Asfarviridae family, genus Asfivirus.
Inmaculada Galindo, Covadonga Alonso
openaire   +5 more sources

Genome sequences of five African swine fever virus genotype IX isolates from domestic pigs in Uganda [PDF]

, 2018
Complete genome sequences of five African swine fever virus isolates were determined directly from clinical material obtained from domestic pigs in Uganda.
Biek, Roman, Da Silva Filipe, Ana, Davison, Andrew J., Masembe, Charles, Mayega, Francis Johnson, Muwanika, Vincent B., Ogweng, Peter, Palmarini, Massimo, Sreenu, Vattipally B., Wilkie, Gavin S.   +9 more
core   +3 more sources

Structure and function of African swine fever virus proteins: Current understanding

Frontiers in Microbiology, 2023
African swine fever virus (ASFV) is a highly infectious and lethal double-stranded DNA virus that is responsible for African swine fever (ASF). ASFV was first reported in Kenya in 1921.
Si-Yong Yang, Chun Miao, Wei Liu, Guanglei Zhang, Junjun Shao, Huiyun Chang   +5 more
semanticscholar   +1 more source

Seroimmunotyping of African swine fever virus

Frontiers in Microbiology, 2023
The extreme genetic and immunobiological heterogeneity exhibited by the African swine fever virus (ASFV) has been a significant impediment in the development of an efficacious vaccine against this disease. Consequently, the lack of internationally accepted protocols for the laboratory evaluation of candidate vaccines has become a major concern within ...
Alexey D. Sereda, Sanzhi Namsrayn, Vladimir M. Balyshev, Mikhail E. Vlasov, Irina P. Sindryakova, Galina Koltsova, Denis V. Kolbasov   +6 more
openaire   +3 more sources