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African Swine Fever Virus

1985
African swine fever (ASF) was first described in 1921 by Montgomery, who reported several disease outbreaks of domestic pigs in Kenya since 1910 with a mortality close to 100%. Montgomery recognized the viral nature of the disease, its likely transmission by wild swine which probably acted as virus carriers, and the lack of protection by passive ...
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African swine fever virus attachment protein

Journal of Virology, 1991
Treatment of African swine fever virus particles with nonionic detergents released proteins p35, p17, p14, and p12 from the virion. Of these proteins, only p12 bound to virus-sensitive Vero cells but not to virus-resistant L or IBRS2 cells. The binding of p12 was abolished by whole African swine fever virus and not by similar concentrations of subviral
A L, Carrascosa, I, Sastre, E, Viñuela
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African Swine Fever Virus Host–Pathogen Interactions

2023
African swine fever virus is a complex double-stranded DNA virus that exhibits tropism for cells of the mononuclear phagocytic system. Virus replication is a multi-step process that involves the nucleus of the host cell as well the formation of large perinuclear sites where progeny virions are assembled prior to transport to, and budding through, the ...
Christopher L, Netherton   +4 more
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African swine fever virus interaction with microtubules

Biology of the Cell, 1993
Summary—The role of microtubules in intracellular transport of African swine fever virus (ASFV) and virus‐induced inclusions was studied by immunofluorescence using anti‐ASFV and anti‐tubulin antibodies, by electron microscopy of infected Vero cells and by in vitro binding of virions to purified microtubules.
A P, de Matos, Z G, Carvalho
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African Swine Fever Virus

1990
African swine fever is a devastating disease of swine caused by an icosahedral enveloped DNA virus which grows in the cytoplasm of infected cells. The virus infects domestic pigs and African or European wild boars, and can be transmitted by soft ticks.
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Sedimentation Coefficient of African Swine Fever Virus

American Journal of Veterinary Research, 1980
SUMMARY AND CONCLUSIONS The sedimentation coefficient of the infective unit of African swine fever in tissue culture harvest fluids was measured in a preparative ultracentrifuge. The boundary locator method used also permitted making an estimate of heterogeneity. The sedimentation coefficient ranged from 3,000 to 8,000 Svedberg units, representing many
R, Trautman, I C, Pan, W R, Hess
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Epitopic diversity of African swine fever virus

Virus Research, 1988
African swine fever (ASF) is caused by an icosahedral cytoplasmic, double stranded DNA virus. In the acute form of the disease, pigs die from disseminated intravascular coagulation (DIC) with extensive damage of the free and fixed macrophage systems and the reticular epithelial cells of the thymus; mortality is virtually 100%. In recent years, subacute
I C, Pan   +4 more
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Unveiling African swine fever virus

Science, 2019
Structural Virology African swine fever virus (ASFV) is highly contagious and often lethal. With no vaccine or effective treatment, infections often require large-scale culling of pigs. Wang et al. apply cutting-edge cryo–electron microscopy techniques to determine the structure of this very large DNA virus.
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Transcriptome profiling in swine macrophages infected with African swine fever virus at single-cell resolution

Proceedings of the National Academy of Sciences of the United States of America, 2022
Yuxuan Zheng, Shaoxiong Yu, Qihui Wang
exaly  

Genotype I African swine fever viruses emerged in domestic pigs in China and caused chronic infection

Emerging Microbes and Infections, 2021
Zilong Wang, Wan WANG, Renqiang Liu
exaly  

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