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1985
African swine fever (ASF) was first described in 1921 by Montgomery, who reported several disease outbreaks of domestic pigs in Kenya since 1910 with a mortality close to 100%. Montgomery recognized the viral nature of the disease, its likely transmission by wild swine which probably acted as virus carriers, and the lack of protection by passive ...
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African swine fever (ASF) was first described in 1921 by Montgomery, who reported several disease outbreaks of domestic pigs in Kenya since 1910 with a mortality close to 100%. Montgomery recognized the viral nature of the disease, its likely transmission by wild swine which probably acted as virus carriers, and the lack of protection by passive ...
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1971
The causative agent of African swine fever (ASF) is an icosahedral virus 175 to 215 mv, in diameter. It is sensitive to lipid solvents and contains deoxyribonucleic acid (DNA). Thus far, it appears to have no close relatives among other viruses that infect mammals.
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The causative agent of African swine fever (ASF) is an icosahedral virus 175 to 215 mv, in diameter. It is sensitive to lipid solvents and contains deoxyribonucleic acid (DNA). Thus far, it appears to have no close relatives among other viruses that infect mammals.
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African swine fever virus interaction with microtubules
Biology of the Cell, 1993Summary—The role of microtubules in intracellular transport of African swine fever virus (ASFV) and virus‐induced inclusions was studied by immunofluorescence using anti‐ASFV and anti‐tubulin antibodies, by electron microscopy of infected Vero cells and by in vitro binding of virions to purified microtubules.
A. P. Alves de Matos, Zilda G. Carvalho
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Epitopic diversity of African swine fever virus
Virus Research, 1988African swine fever (ASF) is caused by an icosahedral cytoplasmic, double stranded DNA virus. In the acute form of the disease, pigs die from disseminated intravascular coagulation (DIC) with extensive damage of the free and fixed macrophage systems and the reticular epithelial cells of the thymus; mortality is virtually 100%. In recent years, subacute
M. Shimizu +4 more
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Association of African swine fever virus with the cytoskeleton
Virus Research, 1988The association of African swine fever virus (ASFV) with the cytoskeleton was investigated. Immunofluorescent studies of ASFV infected cells with anti-ASFV serum showed a temporal and spatial development of viral inclusions which moved from a peripheral to a perinuclear location and fused to give a single large perinuclear factory.
A. P. Alves de Matos +2 more
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Interaction of African swine fever virus with macrophages
Virus Research, 1990Morphological data obtained by electron microscopy have shown that African swine fever virus adapted to VERO cells enters swine macrophages, its natural host cell, by a mechanism of receptor-mediated endocytosis. Binding studies with 3H-labeled virus and competition experiments with UV-inactivated virus have shown that the virus entry that leads to a ...
Eladio Viñuela +2 more
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Plaque Formation by African Swine Fever Virus
Nature, 1968FOLLOWING prolonged adaptation to cell cultures, several isolates of African swine fever virus (ASFV) produce cytopathic effects in pig kidney (PK) cells1–3. We have found that at least two such strains, Uganda3 and Hinde1, consistently produce plaques in monolayers of PK cells under solid overlays; this observation has led to the development of a ...
J. Parker, W. Plowright
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1990
African swine fever is a devastating disease of swine caused by an icosahedral enveloped DNA virus which grows in the cytoplasm of infected cells. The virus infects domestic pigs and African or European wild boars, and can be transmitted by soft ticks.
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African swine fever is a devastating disease of swine caused by an icosahedral enveloped DNA virus which grows in the cytoplasm of infected cells. The virus infects domestic pigs and African or European wild boars, and can be transmitted by soft ticks.
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A microtechnique for the titration for african swine fever virus
Archives of Virology, 1980African swine fever virus isolates were titrated in swine monocyte cultures established in microtitre trays. Although technically simpler and less laborious than conventional tube assays the microtitration assay was less sensitive, but for routine and comparative titrations offers distinct advantages.
R. C. Wardley, P. J. Wilkinson
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Unveiling African swine fever virus
Science, 2019Structural Virology African swine fever virus (ASFV) is highly contagious and often lethal. With no vaccine or effective treatment, infections often require large-scale culling of pigs. Wang et al. apply cutting-edge cryo–electron microscopy techniques to determine the structure of this very large DNA virus.
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