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Fluorescence and Colorimetric Analysis of African Swine Fever Virus Based on the RPA-Assisted CRISPR/Cas12a Strategy.

Analytical Chemistry, 2023
It is well-established that different detection modes are necessary for corresponding applications, which can effectively reduce matrix interference and improve the detection accuracy.
Guobin Mao   +8 more
semanticscholar   +1 more source

African Swine Fever Virus L83L Negatively Regulates the cGAS-STING-Mediated IFN-I Pathway by Recruiting Tollip To Promote STING Autophagic Degradation

Journal of Virology, 2023
African swine fever virus (ASFV) is a large double-stranded DNA virus that primarily infects porcine macrophages. The ASFV genome encodes a large number of immunosuppressive proteins. ABSTRACT African swine fever (ASF) is a devastating infectious disease
Mingyang Cheng   +16 more
semanticscholar   +1 more source

Purification of African Swine Fever Virus

2022
African swine fever virus is a cytolytic virus that leads to the apoptosis of both cultured cells and primary macrophages. Cell culture supernatants of virus-infected cells are routinely used for virological and immunological studies, despite differences in the biological behavior between such preparations and highly purified virus.
Gareth L, Shimmon   +5 more
openaire   +2 more sources

African Swine Fever Virus

2009
African swine fever virus (ASFV) is a large, intracytoplasmically-replicating DNA arbovirus and the sole member of the family Asfarviridae. It is the etiologic agent of a highly lethal hemorrhagic disease of domestic swine and therefore extensively studied to elucidate the structures, genes, and mechanisms affecting viral replication in the host, virus-
G. A. Delhon   +3 more
openaire   +3 more sources

Genotyping of African Swine Fever Virus

2022
Molecular methods are routinely used for the differential diagnosis and genetic characterization of viral diseases of livestock. Real-time PCR (qPCR) is known as the gold standard diagnostic method for most diseases and is also used for the detection of African swine fever virus (ASFV) DNA in clinical specimens.
Paulina, Rajko-Nenow, Carrie, Batten
openaire   +2 more sources

African Swine Fever Virus

2020
African swine fever virus introduction to naive swine population leads to high mortality and losses among susceptible animals. ASF epidemic in Russia (2007–to date) and lately in Eastern Europe highlights severe socio-economic consequences of this disease. The disease epidemiology is rather complex in endemic territories since many factors are involved
Alexander Malogolovkin   +2 more
openaire   +2 more sources

Diversity of African swine fever virus

American Journal of Veterinary Research, 1985
SUMMARY An African swine fever virus is an heterogeneous population, consisting of clones having different biological characteristics in respect to hemadsorption, virulence, infectivity, plaque size, and antigenic determinants. The following observations were made: (1) Nonhemadsorbing virus (nhv) have been segregated from field isolates from Haiti (ht ...
I C, Pan, W R, Hess
openaire   +2 more sources

African Swine Fever Virus

1985
African swine fever (ASF) was first described in 1921 by Montgomery, who reported several disease outbreaks of domestic pigs in Kenya since 1910 with a mortality close to 100%. Montgomery recognized the viral nature of the disease, its likely transmission by wild swine which probably acted as virus carriers, and the lack of protection by passive ...
openaire   +3 more sources

African Swine Fever Virus

1971
The causative agent of African swine fever (ASF) is an icosahedral virus 175 to 215 mv, in diameter. It is sensitive to lipid solvents and contains deoxyribonucleic acid (DNA). Thus far, it appears to have no close relatives among other viruses that infect mammals.
openaire   +3 more sources

African swine fever virus interaction with microtubules

Biology of the Cell, 1993
Summary—The role of microtubules in intracellular transport of African swine fever virus (ASFV) and virus‐induced inclusions was studied by immunofluorescence using anti‐ASFV and anti‐tubulin antibodies, by electron microscopy of infected Vero cells and by in vitro binding of virions to purified microtubules.
A. P. Alves de Matos, Zilda G. Carvalho
openaire   +2 more sources

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