Results 21 to 30 of about 28,486 (257)

African swine fever virus attachment protein [PDF]

Journal of Virology, 1991
Treatment of African swine fever virus particles with nonionic detergents released proteins p35, p17, p14, and p12 from the virion. Of these proteins, only p12 bound to virus-sensitive Vero cells but not to virus-resistant L or IBRS2 cells. The binding of p12 was abolished by whole African swine fever virus and not by similar concentrations of subviral
Ángel L. Carrascosa, Isabel Sastre, Eladio Viñuela   +2 more
openalex   +4 more sources

Deletion of DP148R, DP71L, and DP96R Attenuates African Swine Fever Virus, and the Mutant Strain Confers Complete Protection against Homologous Challenges in Pigs

Journal of Virology, 2023
Ongoing outbreaks of African swine fever (ASF) have considerably damaged the pig industry in affected countries. Thus, a safe and effective vaccine is important to control African swine fever spread.
X. Qi, Tao Feng, Zhao Ma, Linlin Zheng, Huanan Liu, Zhengwang Shi, Chao-chao Shen, Pan Li, Pan-Xue Wu, Yi Ru, Dan Li, Zixiang Zhu, H. Tian, Sen Wu, Haixue Zheng   +14 more
semanticscholar   +1 more source

African Swine Fever Virus H240R Protein Inhibits the Production of Type I Interferon through Disrupting the Oligomerization of STING

Journal of Virology, 2023
African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious and acute hemorrhagic viral disease with a high mortality, approaching 100% in domestic pigs.
Guangqiang Ye, Hongyang Liu, Xiaohong Liu, Wei-ye Chen, Jiangnan Li, Dongmin Zhao, G. Wang, Chun-ling Feng, Zhaoxia Zhang, Qiongqiong Zhou, Jun Zheng, Z. Bu, C. Weng, Li Huang   +13 more
semanticscholar   +1 more source

African Swine Fever Virus Envelope Glycoprotein CD2v Interacts with Host CSF2RA to Regulate the JAK2-STAT3 Pathway and Inhibit Apoptosis to Facilitate Virus Replication

Journal of Virology, 2023
African swine fever is a hemorrhagic disease caused by the African swine fever virus (ASFV), which infects pigs of different breeds and ages, with a fatality rate of up to 100%.
Qi Gao, Yunlong Yang, Yizhuo Luo, Xiong-nan Chen, Ting Gong, Dongdong Wu, Yongzhi Feng, Xiaoyu Zheng, Heng Wang, Guihong Zhang, G. Lu, L. Gong   +11 more
semanticscholar   +1 more source

pMGF505-7R determines pathogenicity of African swine fever virus infection by inhibiting IL-1β and type I IFN production

PLoS Pathogens, 2021
Inflammatory factors and type I interferons (IFNs) are key components of host antiviral innate immune responses, which can be released from the pathogen-infected macrophages. African swine fever virus (ASFV) has developed various strategies to evade host
Jiangnan Li, Jie Song, L. Kang, Li Huang, Shixiang Zhou, Liang Hu, Jun Zheng, Changyao Li, Xianfeng Zhang, Xijun He, Dongmin Zhao, Z. Bu, C. Weng   +12 more
semanticscholar   +1 more source

African Swine Fever in Cameroon: A Review

Pathogens, 2021
African swine fever (ASF) is a hemorrhagic contagious porcine disease caused by the African swine fever virus. The disease poses enormous problems to the pork industry with pig mortality ranging from 30% to 100%, depending on the virulence of the virus ...
Ebanja Joseph Ebwanga, Stephen Mbigha Ghogomu, Jan Paeshuyse   +2 more
doaj   +1 more source

African Swine Fever Virus Infection and Cytokine Response In Vivo: An Update

Viruses, 2023
African swine fever (ASF) is a hemorrhagic viral disease of domestic pigs and wild suids (all Sus scrofa) caused by the ASF virus (ASFV). The disease is spreading worldwide without control, threatening pig production due to the absence of licensed ...
G. Franzoni, M. Pedrera, P. Sánchez-Cordón   +2 more
semanticscholar   +1 more source

MGF360-9L Is a Major Virulence Factor Associated with the African Swine Fever Virus by Antagonizing the JAK/STAT Signaling Pathway

mBio, 2022
African swine fever—an acute, febrile, hemorrhagic, highly contacting, and highly lethal disease caused by African swine fever virus (ASFV)—jeopardizes the global pig industry.
Keshan Zhang, Bo Yang, Chao-chao Shen, Ting Zhang, Yu Hao, Da-jun Zhang, Huanan Liu, Xijuan Shi, Guoli Li, Jinke Yang, Dan Li, Zixiang Zhu, H. Tian, Fan Yang, Yi Ru, W. Cao, Jian-hong Guo, Jijun He, Haixue Zheng, Xiang-tao Liu   +19 more
semanticscholar   +1 more source

The A137R Protein of African Swine Fever Virus Inhibits Type I Interferon Production via the Autophagy-Mediated Lysosomal Degradation of TBK1

Journal of Virology, 2022
African swine fever (ASF) is a lethal viral disease of pigs caused by African swine fever virus (ASFV). No commercial vaccines and antiviral treatments are available for the prevention and control of the disease.
Maowen Sun, Shaoxiong Yu, H. Ge, Tao Wang, Yongfeng Li, Pingping Zhou, Li Pan, Yuying Han, Yuying Yang, Yuan Sun, Su Li, Lianfeng Li, H. Qiu   +12 more
semanticscholar   +1 more source

Point-of-service diagnostic technology for detection of swine viral diseases

Journal of Veterinary Research, 2020
A research project is underway aiming to develop a field diagnostic tool for six important viruses of the pig sector, namely: African swine fever virus (ASFV), porcine reproductive and respiratory syndrome virus (PRRSV), swine influenza virus (SIV ...
Nannucci Lapo, Barattini Paolo, Bossis Ioannis, Woźniakowski Grzegorz, Balka Gyula, Pugliese Carolina   +5 more
doaj   +1 more source