Results 21 to 30 of about 129,645 (160)

A comparative study of PF‐06438179/GP1111 (an infliximab biosimilar) and reference infliximab in patients with moderate to severe active rheumatoid arthritis: A subgroup analysis

International Journal of Rheumatic Diseases, Volume 23, Issue 7, Page 876-881, July 2020., 2020
Abstract Aim PF‐06438179/GP1111 (PF‐SZ‐IFX) is a biosimilar of reference infliximab (Remicade®). This analysis compared the efficacy of PF‐SZ‐IFX and reference infliximab sourced from the European Union (IFX‐EU) in patient subgroups from a randomized, comparative study of PF‐SZ‐IFX versus IFX‐EU.
Hideto Kameda, Eishi Uechi, Tatsuya Atsumi, Carlos Abud‐Mendoza, Kazumasa Kamei, Tsugumi Matsumoto, Dario Ponce de Leon, Muhammad I. Rehman, Min Zhang, Sebastiao C. Radominski   +9 more
wiley   +1 more source

Impact of Saliva and Cariogenic Microbiota on the Chemotherapy‐Induced Oral Mucositis in Oncopediatric Patients: A Preliminary Longitudinal Study

International Journal of Dentistry, Volume 2020, Issue 1, 2020., 2020
This study aims to evaluate the salivary parameters and cariogenic microbiota of pediatric oncological patients and their correlation with severe oral mucositis (SOM). A preliminary longitudinal study included patients in the age range from 4 to 18 years (n = 26), with diagnosis of primary cancer, who were followed up before and after time intervals of
Raphael Cavalcante Costa, Paula Maria Maracajá Bezerra, Lecidamia Cristina Leite Damascena, Isabella Lima Arrais Ribeiro, Paulo Rogério Ferreti Bonan, Simone Alves de Sousa, Leopoldina de Fátima Dantas Almeida, Ana Maria Gondim Valença, Andrea Scribante   +8 more
wiley   +1 more source

The History of Methicillin‐Resistant Staphylococcus aureus in Brazil

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2020, Issue 1, 2020., 2020
Since the emergence of MRSA in the 1960s, a gradual increase in infections by resistant bacteria has been observed. Clinical manifestations may vary from brand to critical condition due to host risk factors, as well as pathogen virulence and resistance.
Mariana Moreira Andrade, Wilson Barros Luiz, Rayane da Silva Oliveira Souza, Jaime Henrique Amorim, Peter J. Weina   +4 more
wiley   +1 more source

Temporal Trend in Selective Cyclooxygenase‐2 Inhibitors Sales in Brazilian Drugstores [PDF]

Pharmacoepidemiol Drug Saf
ABSTRACT Purpose To assess the trends in selective cyclooxygenase‐2 inhibitor anti‐inflammatory drugs (coxibs) sales in Brazil from 2014 to 2021. Methods A time trend analysis of coxibs sales in Brazil from January 2014 to December 2021 was conducted using the Brazilian National Controlled Products Management System.
Biase T, Silva M, Lopes L, Galvao T.
europepmc   +2 more sources

A segurança do paciente cirúrgico na perspectiva da vigilância sanitária — uma reflexão teórica / Surgical patient safety from the perspective of health surveillance — a theoretical reflection

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2014
Diversas medidas de prevenção dos riscos relacionados à assistência e à melhoria da saúde são desenvolvidas em favor da segurança do paciente. A segurança do paciente é entendida como a redução, a um mínimo aceitável, do risco de dano desnecessário ...
Heiko Thereza Santana, Helen Norat Siqueira, Magda Machado de Miranda Costa, Diana Carmem Almeida Nunes de Oliveira, Suzie Marie Gomes, Fabiana Cristina de Sousa, Ana Clara Ribeiro Bello dos Santos, André Anderson Carvalho, Daniel Idelfoncio Lima Lopes, Maria do Socorro Nantua Evangelista   +9 more
doaj   +1 more source

A Simple and Rapid Analytical Method to Detect and Quantify the N‐Nitroso Desmethyl Diltiazem Impurity by Liquid Chromatography‐Tandem Mass Spectrometry in Diltiazem Hydrochloride

SEPARATION SCIENCE PLUS, Volume 8, Issue 5, May 2025.
ABSTRACT N‐nitroso desmethyl diltiazem is a known genotoxic impurity in the cardiovascular drug product diltiazem hydrochloride, raising significant concerns due to its potential carcinogenicity. Detection of such impurities at trace levels is crucial to ensure drug safety and regulatory compliance.
Manoj Kumar Mandapaka, Veeraswami Boddu
wiley   +1 more source

Desafios e perspectivas na vigilância sanitária pós-comercialização/uso

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2019
Trata-se de um ensaio que busca refletir sobre os desafios e as perspectivas para a vigilância pós-comercialização/uso (Vigipós) no Brasil. Com base numa revisão não sistemática da literatura, são apontados alguns desafios como: 1) necessidade de revisão
Mary Anne Fontenele Martins, Ana Paula Coelho Penna Teixeira   +1 more
doaj   +7 more sources

MUSE reveals extended circumnuclear outflows in the Seyfert 1 NGC 7469 [PDF]

, 2020
NGC 7469 is a well known Luminous IR Galaxy, with a circumnuclear star formation ring ($\sim 830$ pc radius) surrounding a Seyfert 1 AGN. Nuclear unresolved winds were previously detected in X-rays and UV, as well as an extended biconical outflow in IR coronal lines.
arxiv   +1 more source

Exploring the Use of Verjuice for Reduced Sodium Pickle Production: Determination of Hedonic and Rejection Thresholds

Journal of Sensory Studies, Volume 40, Issue 2, April 2025.
ABSTRACT Food industry has been searching for strategies to reduce sodium in foods. Verjuice, an acidic juice made from thinned grapes, appears to enhance perceived saltiness in pickles. This study aimed to determine the affective thresholds (Consumer Rejection Threshold: CRT, Compromised Acceptance Threshold: CAT, Hedonic Rejection Threshold: HRT) of ...
Rubia Selmira Lassen, Voltaire Sant'Anna, Fernanda Leal Leães, Tarcísio Lima Filho, Amanda Dupas de Matos   +4 more
wiley   +1 more source

Geodesics in Lewis Spacetime [PDF]

J.Math.Phys. 39 (1998) 3817-3827, 1997
The geodesic equations are integrated for the Lewis metric and the effects of the different parameters appearing in the Weyl class on the motion of test particles are brought out. Particular attention deserves the appearance of a force parallel to the axial axis and without Newtonian analogue.
arxiv   +1 more source