Results 41 to 50 of about 1,783,256 (340)
Determination of Breed Differences in Ag-NORs Occurrence in Pigs
Folia Biologica, 2005 The investigations involved pigs of three breeds: Pietrain, Zlotnicka Spotted and Polish Landrace. The polymorphism in the number and size of nucleolar organizer regions was analyzed in animals of different breeds. It was observed that the average size of Ag-NORs in pigs was higher in chromosome pair 10 than in pair 8.
Maria Bogdzińska +3 more
openaire +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Science Technology and Engineering Journal (STEJ), 2021 The first karyological analysis of the Sternocera ruficornis(Coleoptera, Buprestidae) was achieved by using the squash technique collected from the male gonad.
Nawarat Muanglen +4 more
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Karyotypic evolution of ribosomal sites in buffalo subspecies and their crossbreed
Genetics and Molecular Biology, 2014 Domestic buffaloes are divided into two group based on cytogenetic characteristics and habitats: the "river buffaloes" with 2n = 50 and the "swamp buffaloes", 2n = 48. Nevertheless, their hybrids are viable, fertile and identified by a 2n = 49.
Tiago Marafiga Degrandi +9 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
A new karyotypic formula for the genus Amphisbaena (Squamata: Amphisbaenidae) [PDF]
Phyllomedusa: Journal of Herpetology, 2010 To contribute to the knowledge of chromosome evolution in Amphisbaena, we describe the karyotype constitution and the NOR location of Amphisbaena bolivica Mertens, 1929.
Camila Falcione, Alejandra Hernando
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Genetics and Molecular Biology, 2013 Cytogenetic studies in birds are still scarce compared to other vertebrates. Woodcreepers (Dendrocolaptidae) are part of a highly specialized group within the Suboscines of the New World.
Marcelo de Oliveira Barbosa +5 more
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