Results 61 to 70 of about 183,083 (248)

P7.13 THE P22PHOX -640A/G POLYMORPHISM OF NADPH OXIDASE ADVERSELY AFFECTS ENDOTHELIN LEVELS BUT NOT PERIPHERAL AND CENTRAL PRESSURES IN HEALTHY, YOUNG, NORMOTENSIVE INDIVIDUALS

open access: yesArtery Research, 2009
Purpose: The NADPH oxidase system produces superoxide in the vessel wall and its -640A/G polymorphism is associated with coronary artery disease incidence in young individuals. We investigated the role of this polymorphism on peripheral/aortic pressures (
P. Xaplanteris   +6 more
doaj   +1 more source

Ag-NOR counting for differentiation of follicular thyroid tumours.

open access: yesPathologica, 1995
According to the histological typing system of thyroid tumours adapted by the World Health Organisation follicular tumours are classified as follicular adenomas and follicular carcinomas. The most important diagnostic criterion for follicular carcinoma is the evidence of vascular and/or capsular infiltration.
A, Cör, Z, Pajer
openaire   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Chromosomal characterization of the bonytongue Arapaima gigas (Osteoglossiformes: Arapaimidae)

open access: yesNeotropical Ichthyology
The mitotic chromosomes of the pirarucu Arapaima gigas inhabiting the middle Araguaia River and collected in the municipality of Araguaiana (MT, Brazil) were studied.
Debora Karla Marques   +2 more
doaj   +1 more source

[The diagnostic value of Ag-NOR technique in colorectal cancer].

open access: yesArquivos de gastroenterologia, 1999
The Ag-NOR technique has been applied to many tissues in order to evaluate proliferative lesions. In colorectal mucosa dots counting is not reliable, but the analysis of their shape can be very useful for diagnosis. We applied the Ag-NOR technique to 71 smears of colorectal mucosa, classified in three groups according to the histopathologic diagnosis ...
M, Trevisan, J R, Goes, C, Coy
openaire   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Allozyme and cytogenetic analysis in two species of Hypostomus (Siluriformes: Loricariidae) from the Paraguai River basin, Brazil: occurrence of B microchromosome and intrapopulation heterochromatic polymorphism in H. boulengeri [PDF]

open access: yesNeotropical Ichthyology
Hypostomus is distributed by Central and South America basins, with diverse species with taxonomic conflicts. This way, the integration of auxiliary techniques contributes to understanding the systematics and phylogeny of the group.
Suzana de Paiva   +9 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

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