Results 61 to 70 of about 3,092,948 (244)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Cytogenetic studies in four cultivated Amaranthus (Amaranthaceae) species

Comparative Cytogenetics, 2013
In the present study, the chromosomes numbers were confirmed, 2n = 34 for Amaranthus cruentus Linnaeus, 1759, and 2n = 32 for A. hypochondriacus Linnaeus, 1753, A. mantegazzianus Passer, 1864, and A. caudatus Linnaeus, 1753.
Marisa Bonasora, Lidia Poggio, Eduardo Greizerstein   +2 more
doaj   +1 more source

Silk Fiber as the Support and Reductant for the Facile Synthesis of Ag–Fe3O4 Nanocomposites and Its Antibacterial Properties

, 2016
We report a facile and environmentally friendly approach to prepare Ag–Fe3O4–silk fiber nanocomposites. The Ag–Fe3O4–silk fiber acts as: (i) a biocompatible support for the silver nanoparticles; and (ii) a reducing agent for the silver ions.
Tao Duan, Zao Yi, Guangfu Yin, Xiaonan Liu   +3 more
core   +1 more source

Coverage dependence of the spin-resolved photoemission from epitaxially grown Ag layers on Pt(111) [PDF]

, 1989
Schmiedeskamp B, Kessler B, Vogt B, Heinzmann U. Coverage dependence of the spin-resolved photoemission from epitaxially grown Ag layers on Pt(111). Surface Science.
Schmiedeskamp, B., Vogt, B., Kessler, B., Heinzmann, Ulrich   +3 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

CHROMOSOMES AND Ag-NOR LOCATION IN FLUVIATE POPULATIONS OF SALMO TRUTTA FARIO L. 1758 (SALMONIFORMES: SALMONIDAE) FROM ATACAMA DESERT, CHILE

, 2021
Salmo trutta fario L. 1758, presented a chromosome number 2n = 80 and a fundamental number NF = 100. The haploid chromosome set consists of seven metacentric chromosomes, three submetacentric, one subtelocentric and 29 telocentrics.
Capetillo Arcos, Juana, Jara Seguel, Pedro, Lam, Natalia, Northland Leppe, Irma   +3 more
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Combination of Selective Immunoassays and Mass Spectrometry to Characterize Preproghrelin-Derived Peptides in Mouse Tissues

Frontiers in Neuroscience, 2017
Preproghrelin is a prohormone producing several preproghrelin-derived peptides with structural and functional heterogeneity: acyl ghrelin (AG), desacyl ghrelin (DAG), and obestatin.
Virginie Tolle, Rim Hassouna, Rim Hassouna, Dominique Grouselle, Giovanni Chiappetta, Joanna Lipecka, Oriane Fiquet, Catherine Tomasetto, Joëlle Vinh, Jacques Epelbaum, Jacques Epelbaum   +10 more
doaj   +1 more source

Identification of nucleolus organizer chromosomes in sheep (Ovis aries L.) by sequential GBG/Ag-NOR and RBG/Ag-NOR techniques.

, 1993
Seven Gentile di Puglia sheep (Ovis aries L., 2n = 54) reared in southern Italy were cytogenetically investigated to reveal which chromosomes carry nucleolus organizer regions (NORs).
Ferrara L, Perucatti A, Di Meo GP, Iannuzzi L   +3 more
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source