Results 71 to 80 of about 3,092,948 (244)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

P7.13 THE P22PHOX -640A/G POLYMORPHISM OF NADPH OXIDASE ADVERSELY AFFECTS ENDOTHELIN LEVELS BUT NOT PERIPHERAL AND CENTRAL PRESSURES IN HEALTHY, YOUNG, NORMOTENSIVE INDIVIDUALS

open access: yesArtery Research, 2009
Purpose: The NADPH oxidase system produces superoxide in the vessel wall and its -640A/G polymorphism is associated with coronary artery disease incidence in young individuals. We investigated the role of this polymorphism on peripheral/aortic pressures (
P. Xaplanteris   +6 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Comparative karyotypic study of fifteen cyprinids (Cyprinidae, Cyprininae) species. An insight into the chromosomal evolution of the tribe Systomini.

open access: yesPLoS ONE
The family Cyprinidae is the largest freshwater fish group with 377 genera and over 3,000 described species. However, this group of fish has very limited cytogenetics and advanced molecular cytogenetics information.
Phichaya Buasriyot   +12 more
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Ag-Ag 2 S/reduced graphene oxide hybrids used as long-wave UV radiation emitting nanocomposites

open access: yes, 2017
We report a facile thermal decomposition approach to synthesize Ag-Ag2S/reduced graphene oxide (Ag-Ag2S/rGO), the Ag-Ag2S nanoparticles uniformly dispersed on reduced graphene oxide with diameters of 10–20 nm. The photoluminescence spectra of Ag-Ag2S/rGO
R. Xu (2956116)   +3 more
core   +3 more sources

Karyotype analysis and variability of Ag-NOR in Crassostrea angulata (Lamarck, 1819)

open access: yes, 2002
Genetic characterization of oyster species is the basis of future breeding programmes by chromosome manipulation. We determined the karyotype of Crassostrea angulata (Lamarck, 1819), and found some differences with regard to previously published reports.
Cross, I., Rebordinos, L., Vega, L.
core  

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

Allozyme and cytogenetic analysis in two species of Hypostomus (Siluriformes: Loricariidae) from the Paraguai River basin, Brazil: occurrence of B microchromosome and intrapopulation heterochromatic polymorphism in H. boulengeri [PDF]

open access: yesNeotropical Ichthyology
Hypostomus is distributed by Central and South America basins, with diverse species with taxonomic conflicts. This way, the integration of auxiliary techniques contributes to understanding the systematics and phylogeny of the group.
Suzana de Paiva   +9 more
doaj   +1 more source

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